Korean J Med.
2004 Mar;66(3):321-325.
A case of autoimmune hepatitis type-1 with p-ANNA strong positivity
- Affiliations
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- 1Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea. syhan@daunet.donga.ac.kr
- 2Department of Clinical Pathology, Dong-A University College of Medicine, Busan, Korea.
Abstract
- Autoimmune hepatitis (AIH) is an undissolved inflammatory process of the liver characterized by the periportal hepatitis on histological examination and serum autoantibody. AIH seems to be partly responsible for chronic liver disease of unknown etiology in Korea. Perinuclear-Antineutrophil nuclear antibody (p-ANNA) are detected in up to 88% of patient with primary sclerosing cholangitis (PSC) and presence of p-ANNA in PSC makes them a reasonable diagnostic maker in conjuction with standard diagnostic test. But p-ANNA in AIH is rare and it's role remain unclear. We report the first case of 39 year-old-female patient with AIH type-1 with p-ANNA strong positivity.
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