Korean J Obstet Gynecol.  2012 Jun;55(6):413-418. 10.5468/KJOG.2012.55.6.413.

Complete hydatidiform mole with a coexistent fetus diagnosed by magnetic resonance imaging

Affiliations
  • 1Department of Obstetrics and Gynecology, Chungbuk National University Hospital, Cheongju, Korea. jeongmed@chungbuk.ac.kr
  • 2Medical Research Institute, Chungbuk National University College of Medicine, Cheongju, Korea.

Abstract

Hydatidiform mole with coexistent fetus is very rare, arising about 1 in 20,000 to 100,000 pregnancies. There are limited data to guide the management and treatment. Also it is a dilemma to decide continuation or termination of pregnancy. We experienced a case of hydatidiform mole with a coexistent fetus which was diagnosed with magnetic resonance imaging in a woman of 13th weeks of pregnancy. After termination of pregnancy, the patient treated with prophylactic chemotherapy. We report the case with a brief review of literature.

Keyword

Hydatidiform mole; Twin; Magnetic resonance imaging

MeSH Terms

Female
Fetus
Humans
Hydatidiform Mole
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Magnetics
Magnets
Pregnancy
Twins

Figure

  • Fig. 1 Transavaginal ultrasound imaging demonstrates multicystic hyperechoic mass (arrow) with coexistent living fetus (arrow head).

  • Fig. 2 Magnetic resonance imaging demonstrates normal fetus (thin arrow) of 13 weeks of pregnancy with anterior wall placenta at the right upper portion of uterus, and multiloculated cystic mass (thick arrow) with high signal intensity on T2-weighted image at the left inferior portion of the uterine cavity. (A, B) Sagittal images. (C) Coronal image. (D) Axial image.

  • Fig. 3 Serum human chorionic gonadotropin (hCG) level before and after treatment.

  • Fig. 4 Microscopic examination shows hydatidiform swelling of the chorionic villi, trophoblastic proliferation, and absence of stroma or blood vessels, which are consistent with complete hydatidiform mole, from molar tissue (A), and normal chorionic villi from coexistent fetus (B) (H&E, ×400).


Reference

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