Yonsei Med J.  2006 Jun;47(3):367-371. 10.3349/ymj.2006.47.3.367.

Clinical Experiences of Cardiac Myxoma

• Yu SH
• Lim SH
• Hong YS
• Yoo KJ
• Chang BC
• Kang MS

• KMID: 1715855
• DOI: http://doi.org/10.3349/ymj.2006.47.3.367

Abstract

Although cardiac myxoma is rare, it is the most common primary cardiac tumor. Seventy-four cases of cardiac myxoma that were surgically treated in our center between August 1980 and February 2005 were retrospectively reviewed. The mean patient age was 50.4+/-15.0 (range 7-80) years, and 53 patients (71.6%) were female. The most common preoperative symptom, occurring in 44 patients, was dyspnea. The interval from onset of symptoms to surgery was 9 months. Seventy cases were located in the left atrium, 3 in the right atrium and 1 in the right ventricle. The myxoma in the right ventricle could not be resected completely, due to severe infiltration. Cardiopulmonary bypass and aortic cross clamp times were 100.4+/-37.1 and 64.8+/-29.8 minutes, respectively. There were no hospital deaths, and 7 patients suffered from postoperative complications including atrial fibrillation in 2 cases. During the follow up period (mean 105.7+/-73.6 months), there was no tumor recurrence and 6 late deaths that were not related to the underlying tumor. There was no evidence of tumor growth in the cases with incomplete resection during the 14-month follow-up. In conclusion, in this study there was no recurrence of tumors after complete resection and surgical resection is considered to be the curative method of treatment for cardiac myxoma.

Keyword

Myxoma; surgical resection; heart

MeSH Terms

Treatment Outcome
Postoperative Complications
Myxoma/physiopathology/*surgery
Middle Aged
Male
Humans
Heart Neoplasms/physiopathology/*surgery
Follow-Up Studies
Female
Child
Aged, 80 and over
Aged
Adult
Adolescent

Reference

1. MacGowan SW, Sidhu P, Aherne T, Luke D, Wood AE, Neligan MC, et al. Atrial myxoma: national incidence, diagnosis and surgical management. Ir J Med Sci. 1993. 162:223–226.

2. Bhan A, Mehrotra R, Choudhary SK, Sharma R, Prabhakar D, Airan B, et al. Surgical experience with intracardiac myxomas: long-term follow-up. Ann Thorac Surg. 1998. 66:810–813.

3. Pinede L, Duhaut P, Loire R. Clinical presentation of left atrial cardiac myxoma. A series of 112 consecutive cases. Medicine (Baltimore). 2001. 80:159–172.

4. Bjessmo S, Ivert T. Cardiac myxoma: 40 years' experience in 63 patients. Ann Thorac Surg. 1997. 63:697–700.

5. Reynen K. Cardiac myxomas. N Engl J Med. 1995. 333:1610–1617.

6. Basso C, Valente M, Poletti A, Casarotto D, Thiene G. Surgical pathology of primary cardiac and pericardial tumors. Eur J Cardiothorac Surg. 1997. 12:730–738.

7. Ha JW, Kang WC, Chung N, Chang BC, Rim SJ, Kwon JW, et al. Echocardiographic and morphologic characteristics of left atrial myxoma and their relation to systemic embolism. Am J Cardiol. 1999. 83:1579–1582.

8. Kosuga T, Fukunaga S, Kawara T, Yokose S, Akasu K, Tayama E, et al. Surgery for primary cardiac tumors. Clinical experience and surgical results in 60 patients. J Cardiovasc Surg. 2002. 43:581–587.

9. Centofanti P, Di Rosa E, Deorsola L, Dato GM, Patane F, La Torre M, et al. Primary cardiac tumors: early and late results of surgical treatment in 91 patients. Ann Thorac Surg. 1999. 68:1236–1241.

10. Jones DR, Warden HE, Murray GF, Hill RC, Graeber GM, Cruzzavala JL, et al. Biatrial approach to cardiac myxomas: a 30-year clinical experience. Ann Thorac Surg. 1995. 59:851–856.

11. Keeling IM, Oberwalder P, Anelli-Monti M, Schuchlenz H, Demel U, Tilz GP, et al. Cardiac myxomas: 24 years of experience in 49 patients. Eur J Cardiothorac Surg. 2002. 22:971–977.

12. Gawdzinski MP, Sypula S. The long term results of treatment of heart myxomas with special attention to very rare myxoma of the right ventricle. J Cardiovasc Surg. 1996. 37:121–129.