Korean J Dermatol.  1979 Feb;17(1):65-71.

Histopathological Study of Erythema Mutiforma

• Cho NJ

Abstract

55 patients which were clinically erythema multiforme and were diagnosed by punch biopsy, were studied clinically and histologically. The results obtained were as follows; l. Erythema multiforme was more common in female than in male and they were most frequently occured in 3rd decade. 2. In most patients individuaIs had various type of skin lesions (macule, papuIe, bullous and iris) and the skin lesions were scattered on the various sites of thc body. 3. 30 patients out of 55 patients had seasonal variation, especially frequently occured in spring k autumn. 4. In the histopathological study while dermal disturbance was a predominant finding in the macular lesion, epidermal necrosis was seen high frequency in bullous & iris lesions, 5. The papillary edema showed in most cases, however 2 cases out of 55 lesions had not papillary edema. 6. The dermal inflammatory infiltrates were composed chiefly of lyrnpho-histiocytic and significant number of eosinophils were present in the inflammatory infiltrate in 27 % of the bullous lesions.

MeSH Terms

Biopsy
Blister
Dronabinol
Edema
Eosinophils
Erythema Multiforme
Erythema*
Female
Humans
Iris
Male
Necrosis
Seasons
Skin
Dronabinol