Korean J Urol.  1976 Sep;17(3):171-176.

Effect of Radiation Therapy for Urogenital Malignant Tumors on Peripheral Lymphocyte Count

Affiliations
  • 1Department of Urology, Kyungpook National University, School of Medicine, Taegu, Korea.

Abstract

The effect of prophylactic postoperative radiotherapy on peripheral lymphocyte count was determined for 20 cases of urogenital malignant tumors (bladder cancer-13 cases, prostatic cancer-4 cases, renal cancer-3 cases). The results were obtained as follows, l) Radiotherapy decreased the white blood cell count by a mean percentage of 16.7% (14.0% for bladder cancer, 16.4% for prostatic cancer. 36.8% for renal cancer, respectively) during the period of first month, but did not alter the granulocyte count. 2) Radiotherapy brought about high degree of decrease of peripheral lymphocyte count by a mean percentage of 47.9% (47. 3% for bladder cancer. 50.0% for prostatic cancer. 32.3% for renal cancer, respectively). 3) The recovery of the radiation-induced lymphocyte deficiency to pre-irradiation level was observed in 1-2 years after completion of radiation therapy (2 years for bladder cancer. 1 1/2 years for prostatic cancer. 1 year for renal cancer. respectively).

Keyword

urogenital tumor; peripheral lymphocyte count; radiation

MeSH Terms

Granulocytes
Kidney Neoplasms
Leukocyte Count
Lymphocyte Count*
Lymphocytes*
Prostatic Neoplasms
Radiotherapy
Urinary Bladder Neoplasms
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