J Korean Rheum Assoc.  2002 Jun;9(2):151-156.

A case of overlap syndrome of systemic sclerosis/ systemic lupus erythematosus/Sjogren's syndrome

• Park BH
• Park W
• Lee YH
• Kim SS
• Kim HS
• Kwak YG
• Song JS

Abstract

Overlap syndrome is a combination of major features of more than one rheumatic disease present in the same patient and often defined by a specific serologic test. Overlap syndrome consistent with systemic sclerosis (SSc) and systemic lupus erythematosus (SLE) has been reported in a few cases. Overlap syndrome with SSc and SLE combined with Sjogren's syndrome (SS) is rarely reported worldwide. In Korea, this is the first case report. A 33 year-old female visited our rheumatology clinic complaining of Raynaud' s phenomenon. She was diagnosed as SSc 6 years ago. Clinical and laboratory finding revealed that she has affected by SLE. She also complained dry mouth and dry eye. Finally, she was diagnosed as overlap syndrome consistent with SSc and SLE combined with SS. The authors report a case of overlap syndrome consistent with SSc, SLE, and SS with relevant literatures.

Keyword

Overlap syndrome; Systemic Sclerosis; Systemic Lupus Erythematosus; Sjogren's Syndrome

MeSH Terms

Adult
Female
Humans
Korea
Lupus Erythematosus, Systemic
Mouth
Rheumatic Diseases
Rheumatology
Scleroderma, Systemic
Serologic Tests
Sjogren's Syndrome