J Korean Rheum Assoc.  2002 Jun;9(2):146-150.

A Case of Calcium Pyrophosphate Dihydrate Crystal Deposition Disease Associated with Gout

• Juhng H
• Lee SS
• Kim YA

Abstract

Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease has various patterns of clinical manifestation ranging from an absence of symptoms to a severely destructive arthropathy. A number of metabolic diseases and physiologic stresses, such as aging and trauma, have been associated with CPPD crystal deposition. The coexistence of CPPD crystal deposition disease and gout varies from 2 to 8%. The mechanism of this association has been postulated to be a predisposition to the local deposition of pyrophosphate due to the presence of urate crystal, perhaps acting as a nucleating agent or factor which predispose to the deposition of both kinds of crystals. In Korea, although it is considered that CPPD crystal deposition occasionally coincides monosodium urate crystal, it has not been reported so far. We report a case with CPPD crystal deposition disease combined with gout in a patient who has suffered from osteoarthritis, which is diagnosed by polarized microscopic examination of synovial fluid.

Keyword

CPPD crystal deposition disease; Gout

MeSH Terms

Aging
Calcium Pyrophosphate*
Calcium*
Gout*
Humans
Korea
Metabolic Diseases
Osteoarthritis
Synovial Fluid
Uric Acid
Calcium
Calcium Pyrophosphate
Uric Acid