Korean J Infect Dis.  1999 Oct;31(5):435-438.

Pulmonary Inflammatory Pseudotumor Presenting as Fever of Unknown Origin

• Choi SY
• Cho YK
• Bai IK
• Hong SS
• Lee MS
• Chung DR
• Wo JH
• Ryu JS

Abstract

Inflammatory pseudotumor (IPT) is an uncommon benign neoplasm of unknown etiology presenting as an incidental mass, fever, malaise, anemia, and weight loss. Generally, IPT in the lung is asymptomatic. A case of pulmonary IPT presenting as prolonged fever in a 59 year old man is presented with clinicopathological findings. The patient had been febrile for three months before admission. Five months before admission, a chest X-ray showed a small left pulmonary mass which was regarded as old tuberculosis. An chest X-ray taken on admission revealed a left pulmonary mass two times the size of the one on the first x-ray. Percutaneous needle aspiration and biopsy were performed, and the microscopic examination revealed a plasma cell reaction with myofibroblastic proliferation, consistent with IPT. As prolonged unexplained fever is a frequent symptom in patients with IPTs, this disease entity should be included in the differential diagnosis of fever of unknown origin.

Keyword

Inflammatory pseudotumor of the lung; Fever of unknown origin

MeSH Terms

Anemia
Biopsy
Diagnosis, Differential
Fever of Unknown Origin*
Fever*
Granuloma, Plasma Cell
Humans
Lung
Middle Aged
Myofibroblasts
Needles
Plasma Cell Granuloma, Pulmonary*
Plasma Cells
Thorax
Tuberculosis
Weight Loss