J Korean Neurol Assoc.
2007 May;25(2):229-231.
A Case of Dopamine Dysregulation Syndrome with Concurrent Parkinsonism Hyperpyrexia Syndrome
- Affiliations
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- 1Department of Neurology, Korea University College of Medicine, Korea. parkinson@korea.ac.kr
- 2Department of Neurology, Kangwon National University College of Medicine, Korea.
Abstract
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A few patients with Parkinson's disease (PD) crave large amounts of levodopa therapy far beyond those needed to alleviate their symptoms, even in the state of overdose complication. Such harmful pattern of compulsive dopaminergic drug use is called as dopamine dysregulation syndrome (DDS). We report a chronic stage PD patient presenting with high fever and altered mentality, who had the DDS as well as the Parkinsonism hyperpyrexia syndrome (PHS).