J Korean Geriatr Soc.  2004 Mar;8(1):20-27.

The Neurops ychologic Features of Alcohol-Related Dementia

Affiliations
  • 1Department of Neurology, Gimhae Hansol Hospital, 621 Bowon-dong, Gimhae, 621-907, Korea. neurology@lycos.co.kr
  • 2Department of Psychiatry, Busan Dongin Geriatric Hospital, Busan, Korea.
  • 3Department of Neurology, Seoul National University College of Medicine, Seoul, Korea.
  • 4Department of Radiology, Catholic University of Korea St . Vincent 's Hospital, Suwon, Korea.
  • 5Department of Diagnostic Radiology, Ajou University College of Medicine, Suwon, Korea.
  • 6Department of Neurology, Seoul Metropolitan Seodaemun Hospital, Seoul, Korea.

Abstract

BACKGROUND: Recent studies indicate that heavy alcohol drinking is a significant factor for dementia. There are little studies for the neupsychology of alcohol-related persistent dementia patients in Korea. The main purpose of our study is investigate the results of neuropsychological test and neuroimaging of alcoholic dementia.
METHODS
Eleven inpatients meeting DSM-IVcriteria for alcohol-related persistent dementia were examined with careful history taking, Seoul neuropsychological screening battery and brain CT.
RESULTS
The mean K-MMSE, CDR scores were 18.4+/-3.8, 1.4+/-0.5, respectively. Language functions including spontaneous speech, comprehension, repetition, reading, writing were almost normal, except K-BNT. Attention, visuospatial function, calculation, orientation, memory, frontal executive function were severely impaired. Diffuse brain atrophy was the main finding on the brain CT. Personality changes including impulsivity, apathy, lack of motivation were observed most of the patients.
CONCLUSION
Alcohol-induced persistent dementia subjects were impaired on the test of attention, visuospatial function, calculation, orientation, memory, frontal related function, but language function was relatively preserved.

Keyword

Alcohol; Dementia; Neuropsychology

MeSH Terms

Alcohol Drinking
Alcoholics
Apathy
Atrophy
Brain
Comprehension
Dementia*
Executive Function
Humans
Impulsive Behavior
Inpatients
Korea
Mass Screening
Memory
Motivation
Neuroimaging
Neuropsychological Tests
Neuropsychology
Seoul
Writing
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