Chonnam Med J.  2006 Dec;42(3):223-226.

A Case of Peripheral Corneal Ulceration Associated with Autoimmune Hepatitis

Affiliations
  • 1Department of Ophthalmology, Chonnam National University Medical School and Chonnam National University Research Institute of Medical Sciences, Gwangju, Korea. kcyoon@chonnam.ac.kr
  • 2Department of Pathology, Chonnam National University Medical School and Chonnam National University Research Institute of Medical Sciences, Gwangju, Korea.

Abstract

We report a case of unilateral peripheral ulcerative keratitis associated with autoimmune hapatitis. A 55-year-old woman was admitted due to pain of the left eye. She had history of autoimmune hepatitis and steroid-induced glaucoma. Ocular examination showed an epithelial defect stained with fluorescein, stromal melting, and ciliary injection in the superonasal limbus of the left eye. Tests for antinuclear antibody, anti-smooth muscle antibody, antineutrophil cytoplasmic antibody, and anti-double-stranded deoxyribonucleic acid antibody were positive. The special stain and cultures for micro-organisms from the corneal lesion were negative. She was treated with topical and systemic steroids. Three months after treatment, the peripheral corneal lesion was healed completely.

Keyword

Autoimmune hepatitis; Peripheral corneal ulceration

MeSH Terms

Antibodies, Antineutrophil Cytoplasmic
Antibodies, Antinuclear
Corneal Ulcer*
DNA
Female
Fluorescein
Freezing
Glaucoma
Hepatitis, Autoimmune*
Humans
Middle Aged
Steroids
Antibodies, Antineutrophil Cytoplasmic
Antibodies, Antinuclear
DNA
Fluorescein
Steroids
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