Korean J Dermatol.
2011 Dec;49(12):1079-1082.
Pemphigus Erythematosus
- Affiliations
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- 1Department of Dermatology, School of Medicine, Gyeongsang Institute of Health Science, Gyeongsang National University, Jinju, Korea. cykim@gnu.ac.kr
Abstract
- Pemphigus is a group of blistering autoimmune diseases that affect the skin and mucous membranes with autoantibodies against desmoglein. Among the pemphigus subtypes, pemphigus erythematosus is one of the rare lupus-like variant subtypes of pemphigus that shares common clinical and histopathological manifestations with systemic lupus erythematosus. The lesions appear clinically as erythematous erosive patches on the face in a butterfly distribution, and they manifest subcorneal acantholysis histopathologically. There is concomitant basement membrane zone deposition of immunoglobulin and complement in lesional skin in addition to intercellular space staining in the epidermis. Two cases of pemphigus erythematosus have been reported domestically. Here, we report a case of pemphigus erythematosus in an 18-year old woman.
