J Korean Med Sci.  1994 Apr;9(2):162-168. 10.3346/jkms.1994.9.2.162.

Epstein-Barr virus associated posttransplant malignant lymphoma in renal allograft recipients

Affiliations
  • 1Department of Clinical Pathology, Catholic University Medical College, Seoul, Korea.

Abstract

We report two cases of posttransplant malignant lymphoma(PTML) of B cell origin associated with Epstein-Barr virus(EBV) infection. They were a 52-year-old male and a 37 year-old-female, in whom intermediate-grade diffuse malignant lymphomas of large cell type developed in the submandibular area and jejunum, respectively. DNA and RNA in situ hybridization revealed the presence of EBV-specific DNA and RNA sequences in the tumor cells.


MeSH Terms

Adult
Female
*Herpesvirus 4, Human/isolation & purification
Humans
In Situ Hybridization
Kidney Transplantation/*adverse effects/pathology
Lymphoma/*complications/pathology/virology
Male
Middle Aged
Transplantation, Homologous
Tumor Virus Infections/*complications
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