Yonsei Med J.  2012 Nov;53(6):1220-1223. 10.3349/ymj.2012.53.6.1220.

Arterial Occlusive Disease Complicating Radiation Therapy of Cervical Cancer

• Won KB
• Kim BK
• Ko YG
• Hong MK
• Choi D
• Jang Y

• KMID: 1414268
• DOI: http://doi.org/10.3349/ymj.2012.53.6.1220

Abstract

Radiation-induced arterial disease is caused by significant atherosclerosis in the circumjacent vessels being irradiated. Even though this has been recognized as survival of cancer patients treated with radiotherapy improves, it is a problem that is often under-reported. We present a case of chronic thromboembolic occlusion of right common iliac artery in a 53-year-old woman who was treated with radiation therapy for cervical cancer 13 years ago. We initially performed percutaneous transluminal angioplasty with thrombolytic therapy, but had to cease thrombolytic therapy due to upper gastrointestinal bleeding of Dieulafoy's lesion, nevertheless, achieved good results after revascularization by Fogarty embolectomy.

Keyword

Radiation-induced arterial disease; thromboembolic occlusion; atherosclerosis

MeSH Terms

Arterial Occlusive Diseases/*etiology
Female
Humans
Middle Aged
Radiotherapy/*instrumentation
Uterine Cervical Neoplasms/*radiotherapy

Figure

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  Fig. 1 (A) A lower extremity computed tomographic angiography demonstrates chronic thromboemblic occlusion extending from the right common iliac artery to the popliteal artery. (B) Diagnostic angiography demonstrates total occlusion of right common iliac artery.

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  Fig. 2 The 10×0.5 cm sized organizing thrombi after Redo-Fogarty embolectomy.

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  Fig. 3 A lower extremity computed tomographic angiography demonstrates successful revascularization after Fogarty embolectomy.

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