J Nutr Health.  2014 Aug;47(4):229-235. 10.4163/jnh.2014.47.4.229.

Effects of xylooligosaccharide-sugar mixture on glycemic index (GI) and blood glucose response in healthy adults

• Kyung M
• Choe H
• Jung S
• Lee K
• Jo S
• Seo S
• Choe K
• Yang CK
• Yoo SH
• Kim Y

• KMID: 2327156
• DOI: http://doi.org/10.4163/jnh.2014.47.4.229

Abstract

PURPOSE
The objective of this study was to investigate the effects of xyloologosaccharide (XOS)-sugar mixture on glycemic index (GI) and blood glucose in human subjects.
METHODS
Randomized double-blind cross-over studies were conducted to examine the effect of sucrose with 14% xyloologosaccharide powder (Xylo 14) and sucrose with 20% xylooligosaccharide powder (Xylo 20) on GI and postprandial glucose response at 15, 30, 45, 60, 90, and 120 min.
RESULTS
GIs of Xylo 14 and Xylo 20 were 60.0 +/- 23.5 classified within medium GI range, and 54.3 +/- 17.7 within low GI range, respectively. Xylo 14 and Xylo 20 showed significantly lower area under the glucose curve (AUC) for 0-15 min (p = 0.0113), 0-30 min (p = 0.0004), 0-45 min (p < 0.0001), 0-60 min (p < 0.0001), 0-90 min (p < 0.0001), and 0-120 min (p = 0.0001). In particular, compared with glucose, the blood glucose levels of Xylo 14 and Xylo 20 were significantly lower at every time point between 15 and 120 min.
CONCLUSION
The results of this study suggested that Xylo 14 and Xylo 20 had an acute suppressive effect on GI and the postprandial glucose surge.

Keyword

xylooligosaccharide (XOS); sugar; GI (glycemic index); area under the curve (AUC); blood glucose

MeSH Terms

Adult*
Blood Glucose*
Cross-Over Studies
Glucose
Glycemic Index*
Humans
Sucrose
Blood Glucose
Glucose
Sucrose

Figure

• 

  Fig. 1 Mean blood glucose responses after administration of control food (glucose) and test food (Xylo 14 and Xylo 20). Each value is the mean ± SD. Time points with a p-value indicate a significant difference between groups. Xylo 14, sucrose with 14% xylooligosaccharide powder; Xylo 20, sucrose with 20% xylooligosaccharide powder.

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