Korean J Radiol.  2007 Dec;8(6):541-544. 10.3348/kjr.2007.8.6.541.

Primary Extraskeletal Mesenchymal Chondrosarcoma Arising from the Pancreas

• Oh BG
• Han YH
• Lee BH
• Kim SY
• Hwang YJ
• Seo JW
• Kim YH
• Cha SJ
• Hur G
• Joo M

• KMID: 1089442
• DOI: http://doi.org/10.3348/kjr.2007.8.6.541

Abstract

We report here on a case of primary extraskeletal mesenchymal chondrosarcoma that arose from the pancreas. A 41-year-old man was evaluated by CT to find the cause of his abdominal pain. The CT scans showed a heterogeneously enhancing necrotic mass with numerous areas of coarse calcification, and this was located in the left side of the retroperitoneal space and involved the body and tail of the pancreas. Portal venography via the celiac axis also showed invasion of the splenic vein. Following excision of the mass, it was pathologically confirmed to be primary extraskeletal mesenchymal chondrosarcoma that arose from the pancreas.

Keyword

Mesenchymal chondrosarcoma; Extraskeletal; Pancreas

MeSH Terms

Abdominal Pain/etiology
Adult
Chondrosarcoma, Mesenchymal/complications/*diagnosis/surgery
Contrast Media/administration & dosage
Diagnosis, Differential
Humans
Iohexol/analogs & derivatives/diagnostic use
Male
Necrosis
Pancreas/pathology/radiography
Pancreatic Neoplasms/complications/*diagnosis/surgery
Portal Vein/radiography
Radiographic Image Enhancement/methods
Rare Diseases
Retroperitoneal Space/radiography
Splenic Vein/radiography
Tomography, X-Ray Computed/methods

Figure

• 

  Fig. 1 A. Unenhanced transverse CT scan reveals an ill defined, lobulated mass (arrowheads) of heterogeneously low attenuation that contains numerous areas of coarse calcification (arrows) in the left side of the retroperitoneum. B. On the contrast-enhanced transverse CT scan obtained during the portal venous phase, subtle enhancement is only noted in the periphery of the mass (arrows), and most of the mass remains without enhancement. C. The contrast-enhanced coronal reformatted image shows the ill defined necrotic low attenuated mass (arrowheads) and obliteration of the splenic vein by the mass (thick arrow) with the development of multiple collateral veins (thin arrows). D. Portal venography via the celiac axis also shows obliteration of the splenic vein (thick arrow) by the mass and the development of multiple collateral veins (thin arrows). E. A large multilobulated mass (arrowheads) is located in the body and tail of the pancreas with attachment to the spleen (asterisk) and transverse colon (arrows). F. Light microscopic image shows the typical bimorphic pattern of chondrosarcoma. The chondroid zone (A) is surrounded by a proliferation of undifferentiated cells (B) with abrupt transition. (Hematoxylin & Eosin staining, ×100)

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