Korean J Community Nutr.  2011 Feb;16(1):51-61. 10.5720/kjcn.2011.16.1.51.

Relationship between Nutrients Intakes, Dietary Quality, and Serum Concentrations of Inflammatory Markers in Metabolic Syndrome Patients

• Kim M
• Kim J
• Bae W
• Kim S
• Lee Y
• Na W
• Sohn C

• KMID: 2263805
• DOI: http://doi.org/10.5720/kjcn.2011.16.1.51

Abstract

Elevated serum concentration of inflammation markers is known as an independent risk factor of metabolic syndrome (MS) and dietary intake is an important factor to control MS. The purpose of this study was to investigated the hypothesis that inflammatory indices are associated with dietary intake and diet quality index-international (DQI-I) in subjects with MS. A cross-sectional study was conducted on 156 men and 73 postmenopausal women with MS, defined by three or more risk factors of the modified Adult Treatment Panel III criteria. Serum levels of high sensitive C-reactive protein (hs-CRP), adiponectin were examined and nutrients intake and DQI-I were assessed using a semi-quantitative food frequency questionnaire. The total DQI-I score was significantly higher in female subjects (65.87 +/- 9.86) than in male subjects (62.60 +/- 8.95). There was a positive association between hs-CRP and polyunsaturated fatty acid intake (p < 0.05) and a negative association between adiponectin and lipid (p < 0.05), total sugar (p < 0.01), and total fatty acids (p < 0.05). When the subjects were divided into 5 groups by quintile according to serum adiponectin and hs-CRP level, there was no association between DQI-I score and hs-CRP levels. Moderation score of DQI-I was significantly higher in highest quintile group than the lower quintile groups. Therefore, our results provide some evidence that dietary intake and diet quality are associated with inflammation markers and dietary modification might be a predictor to decrease risk for metabolic syndrome complications. However further research is needed to develop the dietary quality index reflecting the inflammatory change by considering the dietary habit and pattern of Koreans.

Keyword

metabolic syndrome; diet quality index-international; hs-CRP; adiponectin; nutrients intake

MeSH Terms

Adiponectin
Adult
C-Reactive Protein
Cross-Sectional Studies
Diet
Fatty Acids
Female
Food Habits
Humans
Inflammation
Male
Surveys and Questionnaires
Risk Factors
Adiponectin
C-Reactive Protein
Fatty Acids

Figure

• 

  Fig. 1. Comparison of nutrient intakes of the two groups with KDRIs1)(%) DRI for reference : Energy EER2), Protein EAR3), Fiber AI4), Calcium EAR, Phosphorus EAR, Iron EAR, Sodium AI, Zinc EAR, Vitamin A EAR, Vitamin B1 EAR, Vitamin B2 EAR, Vitamin B6 EAR, Niacin EAR, Vitamin C EAR, Folate EAR, Vitamin E AI 1) KDRIs : Dietary Reference Intakes for Koreans 2) EER : Estimated energy requirement 3) EAR : Estimated average requirement 4) RNI : Recommended nutrient intake Significantly different between men and women groups by student's t test at ∗: P < 0.05, ∗∗: P < 0.01 and ∗∗∗: P < 0.001

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