Infect Chemother.  2012 Aug;44(4):250-262. 10.3947/ic.2012.44.4.250.

Overview of Antibiotic Use in Korea

Affiliations
  • 1Department of Internal Medicine, Inje University College of Medicine, Busan, Korea. kimbn@paik.ac.kr

Abstract

Antibiotics are one of the most commonly produced pharmaceutical agents; production amount of antibiotics reached approximately 1.6 trillion won in 2010. From the doctors' perspective, there were important turning points in the use of antibiotics beyond the 21st century. These include implementation of separation of pharmaceutical prescription and dispensation in 2000, quality assessment of prescriptions, including those for antibiotics for treatment of acute upper respiratory tract infections, in ambulatory care in 2001 and public reporting of its results in 2006, quality assessment of the use of prophylactic antibiotics for surgery in 2007, and the code of conduct for ethical competition in the pharmaceutical trade in 2010. With this background, many changes in the use of antibiotics have occurred in the last decade. This review summarizes the literature published on the use of antibiotics in human medicine in Korea over the past decade.

Keyword

Anti-bacterial agents; Prescriptions; Antibiotic prophylaxis; Drug utilization review

MeSH Terms

Ambulatory Care
Anti-Bacterial Agents
Antibiotic Prophylaxis
Drug Utilization Review
Humans
Korea
Prescriptions
Respiratory Tract Infections
Anti-Bacterial Agents

Figure

  • Figure 1 Production of antibiotics (code number 610) in Korea. Source: Korea Food & Drug Administration (http://www.kfda.go.kr/index.kfda?mid=96).

  • Figure 2 Prescription rate of antibiotics for treatment of upper respiratory infection in clinics. All figures are for the fourth quarter of each year. Source: Comprehensive quality report of National Health Insurance 2010 [2].


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Reference

1. Yoon CK. Re-evaluation by the Korean government is urgent 10 years after the introduction of a policy that separates the prescription and dispensing of pharmaceuticals. J Korean Med Assoc. 2011. 54:240–242.
Article
2. Health Insurance Review & Assessment Service. Comprehensive quality report of National Health Insurance 2010. 2011.
3. Ministry of Health and Welfare statistics portal. Accessed 31 July 2012. Available at: http://stat.mw.go.kr/stat/data/cm_data_view.jsp?menu_code=MN03020000&cont_seq=16208.
4. Health Insurance Review & Assessment Service. Quality asessment plan in 2012. Accessed 31 July 2012. Available at: http://hira.or.kr/dummy.do?pgmid=HIRAA020041000000&cmsurl=/cms/notice/02/1210731_13390.html.
5. Korea Pharmaceutical Manufacturers Association. Code of fair competition in pharmaceutical trade. Accessed 31 July 2012. Available at: http://report.kpma.or.kr/notice/View.asp?sn=25.
6. Korea Research-based Pharmaceutical Industry Association. Ethical business practice should be in place in the pharmaceutical industry. Accessed 31 July 2012. Available at: http://members.krpia.or.kr/commons/pop_print.asp?bd_num=534&bd_id=04.
7. Kim YJ, Lee SH, Kang YN, Kim WC, Kim SI, Wie SH, Kim YR, Kang MW. The trend of antibiotic production in Korea during 1981~2003. Infect Chemother. 2005. 37:271–279.
8. Kim SI, Park JM, Wie SH, Kim YR, Kang MW. The trend of antibiotics usage in Korea during 1981-1998. Korean J Infect Dis. 2000. 32:439–447.
9. Korea Food & Drug Administration. 2011 Food and drug statistical yearbook. Accessed 31 July 2012. Available at: http://www.kfda.go.kr/index.kfda?mid=96.
10. Korea Health Industry Development Institute. 2011 Pharmaceutical industry analysis report. Accessed 31 July 2012. Available at: http://www.khiss.go.kr/board/bbs_read.jsp?tname=MINBOARD358&bbsid=B302&bbs_seq=326&jkey=&jword=&pg=2&htxt_code=1253697824500862357829650921550&wj_vcs=.
11. Korea Institute for Health and Social Affairs. 2010 Pharmaceutical consumption and sales census. Accessed 31 July 2012. Available at: http://stat.mw.go.kr/stat/data/cm_data_view.jsp?menu_code=MN01010102&cont_seq=17447.
12. Lee CW, Choi BI. Actual survey of antibiotic use. Korean J Infect Dis. 1990. 22:79–86.
13. Kim DS, Jang SM, Kim NS. Epidemiologic investigation on antibiotic use using defined daily dose. J Korean Acad Manag Care Pharm. 2010. 2:47–59.
14. Lee EK. Analysis of the changes in antibiotic use and resistance. Health Welf Policy Forum. 2003. 77:72–82.
15. Choi EJ, Oh MK, Yang SW, You DS, Sin YJ, Cheong SS, Kim JS. Change of antibiotic sensitivities to causative organisms of urinary tract infection in out patients 2 years before and after the separation of prescription and dispensing medicines. J Korean Acad Fam Med. 2005. 26:88–95.
16. Lee YS, Kim MK, Kim YI, Shin YS, Lee HJ, Ahn HS. Private practitioners' antimicrobial prescription patterns for acute respiratory infections in children. J Korean Public Health Assoc. 1991. 17:3–19.
17. Park S, Moon OR. Patterns of antibiotics utilization in some respiratory diseases in clinics. J Korean Soc Qual Assur Health Care. 1998. 5:58–75.
18. Eo KS, Byeon JJ, Shin HC, Kim CH, Lee JH, Choi YS, Roh YK. Antibiotics prescription pattern of family practitioners for respiratory tract infections. J Korean Acad Fam Med. 2000. 21:901–913.
19. Song YG, Chang KH, Kkim HY, Hong SK, Park YS, Cho JH, Kim CO, Huh AJ, Park ES, Kim YS, Choi YH, Kim JM. Evaluation for appropriateness of therapeutic use of antibiotics in patients with respiratory tract infections and in patients with febrile neutropenia. J Korean Soc Chemother. 2000. 18:125–140.
20. Kim SC, Park YC, Kim BG, Nam DH. Outpatient antibiotic prescription by pediatric and ENT physicians in Ulsan city. Korean J Clin Pharm. 2010. 20:145–150.
21. Yoon JL, Kim MY, Chung MH. Antibiotics in the medications prescribed by pharmacists for the management of upper respiratory infections. J Korean Soc Chemother. 1998. 16:33–42.
22. Cho HJ, Woo SK, Hong CT, Suh EK. Comparison of prescription behaviors between practicing physicians and pharmacists by simulated patients with common cold. J Korean Acad Fam Med. 2001. 22:1394–1399.
23. Cho HJ, Kim CB. Prescription behaviours of office-based doctors to standardized common cold patients in Korea. Pharmacoepidemiol Drug Saf. 2002. 11:401–405.
Article
24. Cho HJ, Kim CB. Discolored nasal discharge did not increase the antibiotic prescription rate for the common cold patients. Pharmacoepidemiol Drug Saf. 2005. 14:139–141.
Article
25. Chung HJ, Lee HJ, Kim ES, Lee JS, Chung MH. Antibiotic prescription by primary care physicians for upper respiratory infections. Infect Chemother. 2007. 39:125–132.
26. Yoo BW, Kang JW, Kim ST, Oh JE, Hong SH, Cho CY. An analysis of outpatient prescription before and after the implementation of the medical reform in an university hospital. J Korean Acad Fam Med. 2002. 23:855–868.
27. Park S, Soumerai SB, Adams AS, Finkelstein JA, Jang S, Ross-Degnan D. Antibiotic use following a Korean national policy to prohibit medication dispensing by physicians. Health Policy Plan. 2005. 20:302–309.
Article
28. Song YK, Lee HK, Ji E, Oh JM. Patterns of antibiotic usage in clinics and pharmacy after separation of dispensary from medical practice. Korean J Clin Pharm. 2011. 21:332–338.
29. Ha KC, Chung MH, Lee JS, Cho R, Lee HK, Kim ES. Medications dispensed by pharmacies for the management of common cold in 2005. Infect Chemother. 2007. 39:1–8.
30. Kim SK. Patterns of antibiotic use in Korea based on quality assessment of prescriptions. J Pharm Policy Res. 2008. 3:68–82.
31. Kim S, Kim HE, Back MS, Lee S. The effect of public report on antibiotics prescribing rate. Korean J Clin Pharm. 2010. 20:242–247.
32. Health Insurance Review & Assessment Service. Results of quality asessment of prescriptions in 2011. Accessed 31 July 2012. Available at: http://hira.or.kr/dummy.do?pgmid=HIRAA020041000000&cmsurl=/cms/notice/02/1211276_13390.html.
33. SNUHMC Institute of Health Policy & Management. Outcome evaluation models for the quality assessment of medical services. Accessed 31 July 2012. Available at: http://www.snu-dhpm.ac.kr/pds/article.html?code=report1&number=1703&keyfield=&key=.
34. Jang SN, Kim NS. Understanding the culture of antibiotics prescribing of primary physicians for acute upper respiratory infection. J Korean Acad Fam Med. 2004. 25:901–907.
35. Kim NS, Jang SN, Jang SM. Factors influencing antibiotics prescribing of primary health physicians in acute upper respiratory infections. J Prev Med Public Health. 2005. 38:1–8.
36. Cho HJ, Hong SJ, Park S. Knowledge and beliefs of primary care physicians, pharmacists, and parents on antibiotic use for the pediatric common cold. Soc Sci Med. 2004. 58:623–629.
Article
37. Kim DS. Physician's belief on antibiotic use in upper respiratory tract infections. HIRA Policy Trend. 2011. 5:33–41.
38. Jo CI, Lim JY, Soo YL. The effect of the degree of competition of the hospital market regions on clinic's rate of antibiotics prescription. KDI J Econ Policy. 2008. 30:132–155.
39. Choi KH, Park SM, Lee JH, Kwon S. Factors affecting the prescribing patterns of antibiotics and injections. J Korean Med Sci. 2012. 27:120–127.
Article
40. Kim JS, Park HN, Cho EM, Park WM, Lee SH, Lee HS, Lee SH. Patient knowledge of upper respiratory infections an unnecessary utilization of antibiotics. J Korean Acad Fam Med. 2001. 22:200–211.
41. Kim SO, Kim CB, Woo KS. Consumer's belief on antibioic use. Health Insur Forum. 2004. 3:90–103.
42. Lee SR, Park EW, Cheong YS, Choi EY, Lim SJ, Sung HJ, Kim YJ, Ha SO. Patient's perspective of common cold and health care utilization. Korean J Fam Med. 2009. 30:440–448.
Article
43. Park BJ, Cho YK, Kim SA. Construction of the Korea Elderly Pharmacoepidemiologic Cohort: Drug utilization review of cephalosporins in geriatric inpatients. Pharmacoepidemiol Drug Saf. 2001. 10:487–492.
Article
44. Rheem I, Choi DO, Park WS, Choi EK, Pai H. Individual drug day (IDD) as a measure of antibiotic usage in a university hospital: A new approach. J Korean Soc Chemother. 1998. 16:51–60.
45. Kim BN. Compliance with an infectious disease specialist's advisory consultations on targeted antibiotic usage. J Infect Chemother. 2005. 11:84–88.
Article
46. Park ES, Kim KS, Lee WJ, Jang SY, Choi JY, Kim JM. The economical impacts of surgical site infections. Korean J Nosocomial Infect Control. 2005. 10:57–64.
47. Chang JH, Kim KH, Kwon SM, Yeom SA, Park CS. The effect of surgical site infection on the length of stay and health care costs. Korean J Health Policy Adm. 2011. 21:44–60.
Article
48. Shin YS, Kim YI, Lee YS, Kim CY, Choe KW, Lee HJ. Variations of antimicrobial prescription patterns among some hospitals. Korean J Infect Dis. 1992. 24:271–284.
49. Rheem I, Pai H, Choi EK, Oh HT, Choi DO, Park WS. Usage analysis of surgical prophylaxis of cephalosporins and aminoglycosides in a university hospital. Infect Chemother. 2004. 36:24–31.
50. Choi WS, Song JY, Hwang JH, Kim NS, Cheong HJ. Appropriateness of antibiotic prophylaxis for major surgery in Korea. Infect Control Hosp Epidemiol. 2007. 28:997–1002.
Article
51. Koh JI, Kim YH, Kim ME. Antibiotic prophylaxis practice in urology: A survey of 21 korean medical institutions. Korean J Urogenital Tract Infect Inflamm. 2009. 4:72–79.
52. Sakong P, Lee JS, Lee EJ, Ko KP, Kim CH, Kim Y, Kim YI. Association between the pattern of prophylactic antibiotic use and surgical site infection rate for major surgeries in Korea. J Prev Med Public Health. 2009. 42:12–20.
Article
53. Kim KH, Park CS, Chang JH, Kim NS, Lee JS, Choi BR, Lee BR, Lee KD, Kim SM, Yeom SA. Association between prophylactic antibiotic use and surgical site infection based on quality assessment data in Korea. J Prev Med Public Health. 2010. 43:235–244.
Article
54. Kim DS, Kim NS, Jang SM. The variation of national antibiotics utilization. Infect Chemother. 2006. 38:S1–S28.
55. Kim ES, Park SW, Lee CS, Kwak YG, Moon C, Kim BN. Impact of a national hospital evaluation program using clinical performance indicators on the use of surgical antibiotic prophylaxis in Korea. Int J Infect Dis. 2012. 16:e187–e192.
Article
56. Park JW, Oh JH, Choi HS, Yoo SB, Choe YJ, Park S, Kim JM, Lee KY, Sohn SK, Yun HR, Chun HK, Lee WY. A prospective, multicenter, randomized trial for duration of the prophylactic antibiotics after elective colorectal surgery: 3 days versus 5 days. J Korean Soc Coloproctol. 2010. 26:123–128.
Article
57. Kwak HD, Choi DJ, Woo SU, Kim J, Um JW, Kim SH. Antimicrobial prophylaxis using a 2nd generation cephalosporin after laparoscopic colorectal resection: A randomized trial of 1-day vs. 3-day. J Korean Surg Soc. 2010. 78:385–389.
Article
58. Kim YS, Lee SH, Ahn BK, Baek SU. Dual therapy and triple therapy of prophylactic antibiotics after elective colorectal surgery: A comparative study. J Korean Soc Coloproctol. 2009. 25:14–19.
Article
59. Si Y, Hur H, Kim SK, Jun KH, Chin HM, Kim W, Park CH, Park SM, Lim KW, Kim SN, Jeon HM. The Use of Short-term Antimicrobial Prophylaxis in Elective Surgery for Gastric Cancer. J Korean Gastric Cancer Assoc. 2008. 8:154–159.
Article
60. Min KS, Kim HS, Lee MA, Kim YI, Seo YS, Lee KH, Rhee YE. Prophylactic antibiotics in elective cesarean section. Korean J Obstet Gynecol. 2002. 45:1511–1515.
61. Baek JK, Lee WS, Kim JM, Lee IH, Cho YK, Yang JH. Comparative study of single-dose prophylactic antibiotics after cord clamping vs. multi-dose postoperative antibiotics in operative complications after elective cesarean section. Korean J Obstet Gynecol. 2004. 47:1880–1885.
62. Ko JK, Cho YK, Yang HJ, Park CW, Park JS, Jun JK, Kim MG, Won HS, Lee PR, Kim A. A prospective multicenter randomized study on prophylactic antibiotics use in cesarean section performed at tertiary center. Korean J Obstet Gynecol. 2010. 53:227–234.
Article
63. Kim B, Moon SH, Moon ES, Kim HS, Park JO, Cho IJ, Lee HM. Antibiotic microbial prophylaxis for spinal surgery: Comparison between 48 and 72-hour AMP protocols. Asian Spine J. 2010. 4:71–76.
Article
64. Kang SH, Choi YS, Byun IY, Kim MK. Antibiotic prophylaxis in the operation of the closed mandibular fractures and the efficacy of postoperative antibiotics. J Korean Assoc Oral Maxillofac Surg. 2009. 35:31–34.
65. Kang SH, Yoo JH, Yi CK. The Efficacy of postoperative prophylactic antibiotics in orthognathic surgery: A prospective study in Le Fort I osteotomy and bilateral intraoral vertical ramus osteotomy. Yonsei Med J. 2009. 50:55–59.
Article
66. Lee JW, Lee JY, Kim SM, Kim MJ, Lee JH. Prophylactic antibiotics in intra-oral bone grafting procedures: a prospective, randomized, double-blind clinical trial. J Korean Assoc Oral Maxillofac Surg. 2012. 38:90–95.
Article
67. Kim EK, Jung IU, Choi JW, Eom JS, Hong JP, Lee TJ, Koh KS. Appropriate administration of prophylactic antibiotics in clean operations: A preliminary report. J Korean Soc Aesthetic Plast Surg. 2010. 16:41–44.
68. Jang HS, Choi KH, Yang SC, Han WK. A prospective study of single-dose antibiotic prophylaxis in live donor nephrectomy. Korean J Urol. 2011. 52:115–118.
Article
69. Jeong WK, Park JW, Lim SB, Choi HS, Jeong SY. Cefotetan versus conventional triple antibiotic prophylaxis in elective colorectal cancer surgery. J Korean Med Sci. 2010. 25:429–434.
Article
70. Lee JS, Lee HH, Song KY, Park CH, Jeon HM. The feasibility of short term prophylactic antibiotics in gastric cancer surgery. J Gastric Cancer. 2010. 10:206–211.
Article
71. Jo JH, Lee SH, Ahn BK, Baek SU. Efficacy of 24 hour-administration of antibiotic prophylaxis after elective colorectal surgery. J Korean Surg Soc. 2008. 74:129–133.
72. Song EK, Yoon TR, Park SJ, Park KS, Jung WB. Protocol for administration of prophylactic antibiotics within one hour before the surgical incision in total hip and knee replacement. J Korean Orthop Assoc. 2009. 44:159–164.
Article
73. Song KH, Kang YM, Sin HY, Yoon SW, Seo HK, Kwon S, Shin MJ, Chang CB, Kim TK, Kim HB. Outcome of cefazolin prophylaxis for total knee arthroplasty at an institution with high prevalence of methicillin-resistant Staphylococcus aureus infection. Int J Infect Dis. 2011. 15:e867–e870.
Article
74. Jung SI, Park KH, Kwon KT, Ko KS, Oh WS, Chung DR, Peck KR, Yeom JS, Chang HH, Kim SW, Son JS, Song JH. Relationship between beta-lactam antimicrobial use and antimicrobial resistance in Klebsiella pneumoniae clinical Isolates at 5 tertiary hospitals in Korea. Infect Chemother. 2007. 39:189–195.
75. Song YA, Jung SI, Chang MO, Ban HJ, Jin NC, Kim HK, Park KH, Shin JH, Bae SY. Relationship between antibiotic use and antibiotic resistance in major nosocomial pathogens at a university hospital. Chonnam Med J. 2008. 44:137–143.
Article
76. Yoon YK, Kim MJ, Sohn JW, Park DW, Kim JY, Chun BC. Surveillance of antimicrobial use and antimicrobial resistance. Infect Chemother. 2008. 40:93–101.
Article
77. Bang JH, Song KH, Park WB, Kim SH, Cho JH, Kim HB, Kim NJ, Oh M, Choe KW. A survey on antimicrobial prescriptions and stewardship programs in Korea. Infect Chemother. 2006. 38:316–324.
78. Oh JT, Kim SW, Son JW, Do BH, Han SW, Shin BC, Park JH, Lee JM, Kim NS. The effect of aminoglycoside restriction on the resistance pattern and mortality of nosocomial bacteremia caused by Gram-negative bacilli. Infect Chemother. 2003. 35:192–198.
79. Kim JY, Jo YM, Choi WS, Yoon YK, Jeong HW, Park DW, Sohn JW, Kim YM, Kim MJ. Usefulness of computerized restricted antibiotics use and control program in a tertiary care hospital. Infect Chemother. 2006. 38:235–241.
80. Kim CS, Ryu SY, Kwon KY, Lim JG, Lim TJ, Min BW, Ryoo NH, Cha SD. Change of antimicrobial use density according to application of computerized management program for restriction of antimicrobials use in a university hospital. Korean J Pediatr Infect Dis. 2006. 13:155–162.
Article
81. Ma JE, Kim SK, Kang MK, Jeong YY, Kim HC, Lee JD, Hwang YS. Change of antibiotics resistance pattern of microorganism cultured in tracheal aspirate in mechanical ventilated patients after antibiotics restriction policy. Korean J Crit Care Med. 2008. 23:25–29.
Article
82. Kim SH, Kim MK, Kim KS, Hahn HJ, Son IJ, Lee HS. The effects of the antimicrobial control program by electronic medical record system on the antimicrobial prescriptions. J Korean Soc Health Syst Pharm. 2010. 27:271–280.
Article
83. Kim SW, Park HJ, Oh WS, Kim YS, Chang HH, Jung SI, Chung DR, Lee H, Yeom JS, Ki HK, Son JS, Peck KR, Woo GJ, Song JH. Drug use evaluation of intravenous ciprofloxacin in university hospitals in Korea. Infect Chemother. 2004. 36:350–356.
84. Ro ES, Park YH, Bang EM, Kim WK, Lim KS. A trial of drug use evaluation of oral levofloxacin in the hospitalized patients. Korean J Clin Pharm. 2009. 19:105–109.
85. Lee H, Jung D, Yeom JS, Son JS, Jung SI, Kim YS, Kim CK, Chang HH, Kim SW, Ki HK, Moon CS, Chung DR, Peck KR, Song JH, Woo GJ. Evaluation of ceftriaxone utilization at multicenter study. Korean J Intern Med. 2009. 24:374–380.
Article
86. Park YM, Kim KH, Hong KJ. Drug use evaluation on ceftazidime in a teaching hospital. Korean J Hosp Pharm. 1995. 12:328–333.
87. Kim SM, Bae SM, Hong KJ, La HO, Kim YL, Kang MY. Drug use evaluation on ceftriaxone. Korean J Hosp Pharm. 1999. 16:48–51.
88. Oh JM, Kim EA. Teicoplanin use in a Korean university hospital. Am J Health Syst Pharm. 2003. 60:2256–2257.
Article
89. Sim YH, Kwon HJ, Shin HT, Choe KW. A study of drug utilization review on aminoglycoside antibiotics. J Korean Soc Chemother. 1992. 6:13–19.
90. Kim SJ, Lim SC, Hwang BY, Lee CK, Lee JS, Park SY, Han SY, Lee MK. Drug use evaluation of carbapenem in Korean hospitalized patients. Korean J Clin Pharm. 2007. 17:109–116.
91. Yeom JH, Park JS, Oh OH, Shin HT, Oh JM. Identification of inappropriate drug prescribing by computerized, retrospective DUR screening in Korea. Ann Pharmacother. 2005. 39:1918–1923.
Article
92. Lee JG, Lee YJ, Hwang BY, Jeong H, Jung SJ, Kim SB, Cheong HJ, Kim WJ, Kim MJ, Park SC. Evaluation of the appropriateness of approved antibiotic usage guidlines in Korea: Comparison of domestic package inserts with Physicians' Desk Reference. Infect Chemother. 2003. 35:256–270.
93. Choi SM, Park SH, Lee DG, Choi JH, Yoo JH, Shin WS. Current antimicrobial usage for the management of neutropenic fever in Korea: a nationwide survey. J Korean Med Sci. 2008. 23:941–947.
Article
94. Yoon YK, Kim EJ, Chun BC, Eom JS, Park DW, Sohn JW, Kim MJ. Prescription of antibiotics for adults hospitalized with community-acquired pneumonia in Korea in 2004: a population-based descriptive study. Respirology. 2012. 17:172–179.
Article
95. Song JH, Jung KS, Kang MW, Kim DJ, Pai H, Suh GY, Shim TS, Ahn JH, Ahn CM, Woo JH, Lee NY, Lee DG, Lee MS, Lee SM, Lee YS, Lee H, Chung DR. Treatment guidelines for community-acquired pneumonia in Korea: An evidence-based approach to appropriate antimicrobial therapy. Infect Chemother. 2009. 41:133–153.
Article
96. Park KH, Jung SI, Jang MO, Chang NK, Kim JK. Investigation of prophylactic antibiotic usage for interventional radiology in Korea. Infect Chemother. 2008. 40:266–270.
Article
97. Park WB, Kim HB, Kim NJ, Oh Md, Choe KW, Lee YS, Shin JS. Using problem-based learning to teach antibiotics use during a clerkship in internal medicine. Korean J Med Educ. 2007. 19:13–21.
Article
98. Kim SS, Moon S, Lee ES. Adolescents' knowledge and attitudes towards antibiotic use. J Korean Acad Fundam Nurs. 2009. 16:421–429.
99. Kim SS, Cheon JY, Kwon IS, Cho YM, Moon S. Development and evaluation of a web-based education program on appropriate antibiotic use in Korean adolescents. J Korean Acad Fundam Nurs. 2011. 18:383–391.
100. Lim HH, Kang HJ, Yang EA, Lee JH. Clinical usefulness of procalcitonin as guideline of antibiotic treatment in children with respiratory tract infection. Pediatr Allergy Respir Dis. 2012. 22:110–115.
Article
101. Kim SI, Shim BY, You HY, Jung J, Wie SH, Kim YR, Kang MW. Clinical usefulness of procalcitonin in febrile patients: Comparison with erythrocyte sedimentation rate and C-reactive protein. Korean J Infect Dis. 2000. 32:129–134.
102. Noe EJ, Lee SY, Lee KM, Kim KN. Clinical availability of serum procalcitonin in children with bacterical infection. Korean J Pediatr Infect Dis. 2010. 17:108–113.
Article
103. Choi HJ, Kim SH, Rheu KH, Lee YH, Park JY. The clinical value of procalcitonin in diagnosis of patients with fever. Infect Chemother. 2005. 37:1–8.
104. The Korean Society of Infectious Diseases. Korean Society for Chemotherapy. The Korean Society of Clinical Microbiology. Clinical guideline for the diagnosis and treatment of gastrointestinal infections. Infect Chemother. 2010. 42:323–361.
105. The Korean Society of Infectious Diseases. The Korean Society for Chemotherapy. Korean Association of Urogenital Tract Infection and Inflammation. The Korean Society of Clinical Microbiology. Clinical guideline for the diagnosis and treatment of urinary tract infections: Asymptomatic bacteriuria, uncomplicated & complicated urinary tract infections, bacterial prostatitis. Infect Chemother. 2011. 43:1–25.
106. The Korean Society for AIDS. Clinical guidelines for the diagnosis and treatment of HIV/AIDS in HIV-infected Koreans. Infect Chemother. 2011. 43:89–128.
107. The Korean Society of Infectious Diseases. Korean Society for Chemotherapy. The Korean Society of Clinical Microbiology. The Korean Society of Cardiology. The Korean Society for Thoracic and Cardiovascular Surgery. Clinical guideline for the diagnosis and treatment of cardiovascular infections. Infect Chemother. 2011. 43:129–177.
108. Lee DG, Kim SH, Kim SY, Kim CJ, Park WB, Song YG, Choi JH. Evidence-based guidelines for empirical therapy of neutropenic fever in Korea. Korean J Intern Med. 2011. 26:220–252.
Article
109. Park JS. Korean guidelines for the treatment of tuberculosis. Korean J Med. 2012. 82:269–273.
Article
110. The Korean Society for AIDS. Clinical guidelines for the treatment and prevention of opportunistic infections in HIV-infected Koreans. Infect Chemother. 2012. 44:93–139.
111. The Korean Society of Infectious Diseases. The Korean Society for Chemotherapy. The Korean Neurological Association. The Korean Neurosurgical Society. The Korean Society of Clinical Microbiology. Clinical practice guidelines for the management of bacterial meningitis in adults in Korea. Infect Chemother. 2012. 44:140–163.
112. Chung DR, Song JH. The Korean Society of Infectious Diseases. National campaign for appropriate antibiotic use in Korea. Infect Chemother. 2012. 44:164–167.
Article
113. Kim S, Hur Y. Medical professionalism in the 21st century: How can we teach it? Korean J Med Educ. 2003. 15:171–186.
Article
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