Korean J Med Mycol.
2010 Jun;15(2):77-82.
A Case of Majocchi's Granuloma of the Face of an Immunocompetent Patient Caused by Trichophyton rubrum
- Affiliations
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- 1Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. bkcho@catholic.ac.kr
- 2Department of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea.
Abstract
- Majocchi's granuloma is well recognized but uncommon infection of dermal and subcutaneous tissue by fungal organisms usually limited to the superficial epidermis. The organism most commonly associated with Majocchi's granuloma is Trichophyton(T.) rubrum, however, other dermatophytes may be the causative agent. A 44-year-old male patient presented with a 6 month history of two well defined erythematous nodular plaques on his right jaw and preauricular area. Histopathologic findings were consistent with the Majocchi's granuloma, showing perifolliculitis and granulomatous inflammation in the dermis. Many fungal elements were noted within the giant cells of the perifollicular dermis of PAS stained section. T. rubrum was cultured from the biopsy specimen and confirmed by slide culture. After 10 weeks of terbinafine (Lamisil(R)) therapy (250 mg/day), lesions were cleared with mild erythematous patches and atrophic scars.
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