Yonsei Med J.  2016 May;57(3):714-720. 10.3349/ymj.2016.57.3.714.

A Six-Year Study on the Changes in Airborne Pollen Counts and Skin Positivity Rates in Korea: 2008-2013

Affiliations
  • 1Division of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. cshong@yuhs.ac
  • 2Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.
  • 3Applied Meteorology Research Division, National Institute of Meteorological Science, Jeju, Korea.
  • 4Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea. jaewonoh@hanyang.ac.kr

Abstract

PURPOSE
The occurrence of pollen allergy is subject to exposure to pollen, which shows regional and temporal variations. We evaluated the changes in pollen counts and skin positivity rates for 6 years, and explored the correlation between their annual rates of change.
MATERIALS AND METHODS
We assessed the number of pollen grains collected in Seoul, and retrospectively reviewed the results of 4442 skin-prick tests conducted at the Severance Hospital Allergy-Asthma Clinic from January 1, 2008 to December 31, 2013.
RESULTS
For 6 years, the mean monthly total pollen count showed two peaks, one in May and the other in September. Pollen count for grasses also showed the same trend. The pollen counts for trees, grasses, and weeds changed annually, but the changes were not significant. The annual skin positivity rates in response to pollen from grasses and weeds increased significantly over the 6 years. Among trees, the skin positivity rates in response to pollen from walnut, popular, elm, and alder significantly increased over the 6 years. Further, there was a significant correlation between the annual rate of change in pollen count and the rate of change in skin positivity rate for oak and hop Japanese.
CONCLUSION
The pollen counts and skin positivity rates should be monitored, as they have changed annually. Oak and hop Japanese, which showed a significant correlation with the annual rate of change in pollen count and the rate of change in skin positivity rate over the 6 years may be considered the major allergens in Korea.

Keyword

Allergy; change; correlation; pollen; skin positivity rate; Seoul

MeSH Terms

Allergens/*immunology
Asthma/epidemiology/immunology
Humans
Hypersensitivity/*epidemiology
Pollen/*immunology
Republic of Korea/epidemiology
Retrospective Studies
Rhinitis, Allergic, Seasonal
*Skin Tests

Figure

  • Fig. 1 The mean monthly variation in pollen counts.

  • Fig. 2 The changes of pollen counts for 6 years. (A) In tree, grass, and weed, (B) according to species.

  • Fig. 3 Changes of skin positivity rates to pollens. (A) Total, (B and C) tree, (D) weed. *The skin reactivity rate showed significant increase (p<0.05).

  • Fig. 4 The correlation between changes of pollen counts and changes of skin positivity rates. (A) Alder, (B) birch, (C) oak, (D) elm, (E) ragweed, (F) hop japanese. Oak and hop Japanese showed statistical significance (p<0.05).


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Reference

1. Bajin MD, Cingi C, Oghan F, Gurbuz MK. Global warming and allergy in Asia Minor. Eur Arch Otorhinolaryngol. 2013; 270:27–31.
Article
2. D'Amato G, Cecchi L, Bonini S, Nunes C, Annesi-Maesano I, Behrendt H, et al. Allergenic pollen and pollen allergy in Europe. Allergy. 2007; 62:976–990.
3. Sercombe JK, Green BJ, Rimmer J, Burton PK, Katelaris CH, Tovey ER. London plane tree bioaerosol exposure and allergic sensitization in Sydney, Australia. Ann Allergy Asthma Immunol. 2011; 107:493–500.
Article
4. Subiza Garrido-Lestache J. [Allergenic pollens in Spain]. Allergol Immunopathol (Madr). 2004; 32:121–124.
5. Mehulić M, Mehulić K, Vuljanko IM, Kukulj S, Grle SP, Vukić AD, et al. Changing pattern of sensitization in Croatia to aeroallergens in adult population referring to allergy clinic during a period of 15 years. Coll Antropol. 2011; 35:529–536.
6. Kim CW, Lee JH, Jung HW, Choi SR, Cheong JW, Park JW, et al. Changing patterns of skin reactivity to inhalant allergens in asthmatic patients. J Asthma Allergy Clin Immunol. 2001; 21:205–215.
7. Yoon YW, Lee MK, Park HS, Park SS, Hong CS. The skin test reactivity and the level of the total IgE in the allergic patients. J Asthma Allergy Clin Immunol. 1989; 9:385–398.
8. Park HJ, Lim HS, Park KH, Lee JH, Park JW, Hong CS. Changes in allergen sensitization over the last 30 years in Korea respiratory allergic patients: a single-center. Allergy Asthma Immunol Res. 2014; 6:434–443.
Article
9. Sung MS, Park YJ, Park GH, Oh JW, Kim SW. The correlation between allergy sensitization rate in pediatric and aerobiological study for airborne pollen in Busan for 15 years. Allergy Asthma Respir Dis. 2014; 2:38–47.
Article
10. Lin RY, Clauss AE, Bennett ES. Hypersensitivity to common tree pollens in New York City patients. Allergy Asthma Proc. 2002; 23:253–258.
11. Ariano R, Passalacqua G, Panzani R, Scordamaglia A, Venturi S, Zoccali P, et al. Airborne pollens and prevalence of pollenosis in Western Liguria: a 10-year study. J Investig Allergol Clin Immunol. 1999; 9:229–234.
12. Honda K, Saito H, Fukui N, Ito E, Ishikawa K. The relationship between pollen count levels and prevalence of Japanese cedar pollinosis in Northeast Japan. Allergol Int. 2013; 62:375–380.
Article
13. Gautrin D, Vandenplas O, DeWitte JD, L'Archevêque J, Leblanc C, Trudeau C, et al. Allergenic exposure, IgE-mediated sensitization, and related symptoms in lawn cutters. J Allergy Clin Immunol. 1994; 93:437–445.
Article
14. Adkinson NF Jr, Bochner BS, Burks AW, Busse WW, Holgate ST, Lemanske RF, et al. Middleton's allergy: principles and practice. 8th ed. Philadelphia: Elsevier Saunders;2013.
15. Oh JW. Development of pollen concentration prediction models. J Korean Med Assoc. 2009; 52:579–591.
Article
16. Kim JH, Oh JW, Lee HB, Kim SW, Kang IJ, Kook MH, et al. Changes in sensitization rate to weed allergens in children with increased weeds pollen counts in Seoul metropolitan area. J Korean Med Sci. 2012; 27:350–355.
Article
17. D'Amato G, Cecchi L. Effects of climate change on environmental factors in respiratory allergic diseases. Clin Exp Allergy. 2008; 38:1264–1274.
18. Singer BD, Ziska LH, Frenz DA, Gebhard DE, Straka JG. Research note: increasing Amb a 1 content in common ragweed (ambrosia artemisiifolia) pollen as a function of rising atmospheric CO2 concentration. Funct Plant Biol. 2005; 32:667–670.
Article
19. Oh JW, Lee HB, Kang IJ, Kim SW, Park KS, Kook MH, et al. The revised edition of Korean calendar for allergenic pollens. Allergy Asthma Immunol Res. 2012; 4:5–11.
Article
20. Ariano R, Canonica GW, Passalacqua G. Possible role of climate changes in variations in pollen seasons and allergic sensitizations during 27 years. Ann Allergy Asthma Immunol. 2010; 104:215–222.
Article
21. Lee JU, Kim JD, Park CS. Gene-environment interactions in asthma: genetic and epigenetic effects. Yonsei Med J. 2015; 56:877–886.
Article
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