Yonsei Med J.  2000 Feb;41(1):22-28. 10.3349/ymj.2000.41.1.22.

Dietary iodine intake and urinary iodine excretion in patients with thyroid diseases

Affiliations
  • 1Department of Food and Nutrition, College of Human Ecology, Yonsei University College of Medicine, Seoul, Korea.
  • 2Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. kimkr96@yumc. yonsei.ac.kr

Abstract

This study was conducted to examine the usual iodine intake in patients with thyroid diseases and to compare iodine status with normal subjects. The dietary iodine intake was assessed using a semi-quantitative food frequency questionnaire, and urinary iodine excretion was measured in 184 patients diagnosed with thyroid diseases and 207 normal subjects. The average usual iodine intake of patients with thyroid diseases was 673.8 +/- 794.9 ug/day and that of normal subjects was 468.9 +/- 481.9 ug/day. Among the patients with thyroid diseases, higher values were found in the patients with thyroid cancer (1460.6 +/- 1044.8 ug/day) and lower values were found in patients with simple goiter (443.5 +/- 470.4 ug/day). The urinary iodine excretions of patients and normal subjects were 4.33 +/- 5.70 mg/L and 2.11 +/- 0.69 mg/L, respectively. The iodine intake and urinary iodine excretion of patients with thyroid diseases were significantly higher than those of normal subjects (p < 0.05). The dietary iodine intake and urinary excretion of patients with thyroid cancer were significantly higher than other patients with thyroid diseases and normal subjects because of the use of seaweed or seaweed-containing dietary supplements (p < 0.01). This study suggests that the habitual ingestion of seaweed-containing dietary supplements in addition to dietary iodine intake will have adverse effects due to its excessive iodine intake.

Keyword

Iodine intake; urinary iodine excretion; thyroid diseases; seaweed-based dietary supplements

MeSH Terms

Adult
Diet
Dietary Supplements
Female
Human
Iodine/urine*
Iodine/administration & dosage*
Male
Middle Age
Reference Values
Seaweed
Thyroid Diseases/urine*

Cited by  7 articles

Effect of a Low Iodine Diet vs. Restricted Iodine Diet on Postsurgical Preparation for Radioiodine Ablation Therapy in Thyroid Carcinoma Patients
Chi Young Lim, Jung-Yeon Kim, Mi-Jin Yoon, Hang Seok Chang, Cheong Soo Park, Woong Youn Chung
Yonsei Med J. 2015;56(4):1021-1027.    doi: 10.3349/ymj.2015.56.4.1021.

Dietary evaluation of a low-iodine diet in Korean thyroid cancer patients preparing for radioactive iodine therapy in an iodine-rich region
Dal Lae Ju, Young Joo Park, Hee-Young Paik, Min-Ji Kim, Seonyeong Park, Kyong Yeun Jung, Tae Hyuk Kim, Hun Sung Choi, Yoon Ju Song
Nutr Res Pract. 2016;10(2):167-174.    doi: 10.4162/nrp.2016.10.2.167.

Evaluation of Thyroid Hormone Levels and Urinary Iodine Concentrations in Koreans Based on the Data from Korea National Health and Nutrition Examination Survey VI (2013 to 2015)
Jae Hoon Chung
Endocrinol Metab. 2018;33(2):160-163.    doi: 10.3803/EnM.2018.33.2.160.

Update on Thyroid Hormone Levels and Thyroid Dysfunction in the Korean Population Based on Data from the Korea National Health and Nutrition Examination Survey VI (2013 to 2015)
Jae Hoon Chung
Endocrinol Metab. 2020;35(1):7-13.    doi: 10.3803/EnM.2020.35.1.7.

Dietary iodine intake and the association with subclinical thyroid dysfunction in male workers
Eun Hye Kim, Tae-in Choi, Yoo Kyoung Park
Korean J Nutr. 2012;45(3):218-228.    doi: 10.4163/kjn.2012.45.3.218.

An Iodine Database for Common Korean Foods and the Association between Iodine Intake and Thyroid Disease in Korean Adults
Mi-Rhan Han, Dal Lae Ju, Hee-Young Paik, YoonJu Song, Young Joo Park
Int J Thyroidol. 2015;8(2):170-182.    doi: 10.11106/ijt.2015.8.2.170.

Determination of Urinary Iodine Concentration by Inductively Coupled Plasma-mass Spectrometry in Thyroid Cancer Patients on Low-iodine Diet
Ji Hyun Lee, Ok-Ja Ji, Min-Jung Song, Hyung-Doo Park, Hee Kyung Kim, Sun Wook Kim, Jae Hoon Chung, Soo-Youn Lee
Korean J Lab Med. 2010;30(4):351-356.    doi: 10.3343/kjlm.2010.30.4.351.

Full Text Links
  • YMJ
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr