Yonsei Med J.  1990 Sep;31(3):225-233. 10.3349/ymj.1990.31.3.225.

Chlorophyll derivatives (CpD) extracted from silk worm excreta are specifically cytotoxic to tumor cells in vitro

Affiliations
  • 1Department of Microbiology, Yonsei University College of Medicine, Seoul, Korea.
  • 2Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Applied Chemistry, Ajou University, Suwon, Korea.
  • 4Department of Chemistry, Ajou University, Suwon, Korea.


MeSH Terms

Animal
Antineoplastic Agents, Phytogenic/isolation & purification/*pharmacology
Chlorophyll/*analogs & derivatives/isolation & purification/pharmacology/radiation effects
Comparative Study
Drug Screening Assays, Antitumor
Feces/*chemistry
Hematoporphyrin Derivative
Hematoporphyrins/pharmacology
Human
Leukocytes, Mononuclear/drug effects
Mice
Oxygen/metabolism
Photochemistry
Photochemotherapy
Radiation-Sensitizing Agents/isolation & purification/*pharmacology
Silkworms/*metabolism
Singlet Oxygen
Spectrophotometry
Structure-Activity Relationship
Support, Non-U.S. Gov't
Tumor Cells, Cultured/*drug effects/radiation effects
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