J Korean Med Sci.  2013 Jun;28(6):876-880. 10.3346/jkms.2013.28.6.876.

Association between Metabolic Syndrome and Gallbladder Polyps in Healthy Korean Adults

Affiliations
  • 1Department of Family Medicine, Ewha Womans University College of Medicine, Mokdong Hospital, Seoul, Korea. ewhashim@ewha.ac.kr

Abstract

The goal of this study was to evaluate the association between gallbladder (GB) polyps and metabolic syndrome. A total of 5,685 healthy subjects were included, and 485 of these subjects had GB polyps and 744 had metabolic syndrome. In this study, metabolic syndrome was diagnosed according to standards suggested by the AHA/NHLBI ATP III 2005, and abdominal obesity (> or = 90 cm in men and > or = 85 cm in women for Korean) was diagnosed according to standards set forth by the Korean Society for Study of Obesity. Biphasic logistic regression adjusted for age and gender was used to evaluate the association between metabolic syndrome and GB polyps. Subjects who were male (OR, 1.493; 95% CI, 1.11-2.00) and hepatitis B suface Ag (HBsAg) positive (OR, 1.591; 95% CI, 1.06-2.38) were significantly more likely to have GB polyps. The metabolic syndrome group had a higher risk of GB polyps (OR, 1.315; 95% CI, 1.01-1.69) than the group without metabolic syndrome. In conclusion, subjects who were HBsAg positive and male appear to be associated with the risk of GB polyps. The presence of metabolic syndrome also appears to be associated with the risk of GB polyps in Koreans.

Keyword

Metabolic Syndrome; GB Polyp; Risk Factors

MeSH Terms

Adult
Age Factors
Asian Continental Ancestry Group
Female
Gallbladder Diseases/*diagnosis/etiology
Hepatitis B Surface Antigens/blood
Humans
Logistic Models
Male
Metabolic Syndrome X/complications/*diagnosis
Middle Aged
Odds Ratio
Republic of Korea
Risk Factors
Severity of Illness Index
Sex Factors
Hepatitis B Surface Antigens

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