J Korean Rheum Assoc.  2010 Dec;17(4):412-416. 10.4078/jkra.2010.17.4.412.

A Case of CPPD Crystal Deposition Disease in a Patient with Rheumatoid Arthritis and Systemic Sclerosis

Affiliations
  • 1Department of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea. choong@wmbh.co.kr

Abstract

Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease is an inflammatory arthropathy that is defined by the deposition of CPPD crystals in articular and periarticular structures. CPPD crystal deposition disease has various clinical manifestation patterns ranging from an absence of symptoms to a severely destructive arthropathy. CPPD crystal deposition disease very rare with rheumatoid arthritis or systemic sclerosis. We report a case of CPPD crystal deposition disease combined in a patient with rheumatoid arthritis and systemic sclerosis.

Keyword

Rheumatoid arthritis; Calcium pyrophosphate dihydrate crystal deposition disease

MeSH Terms

Arthritis, Rheumatoid
Calcium Pyrophosphate
Diphosphates
Humans
Scleroderma, Systemic
Calcium Pyrophosphate
Diphosphates

Figure

  • Fig. 1. Plain radiographs show punctate and linear radiodense deposits in the fibrocartilaginous periarticular joint articular hyaline cartilage (chondrocalcinosis).

  • Fig. 2. Computed tomography scan showing nodular calcified deposit in the distal humerus and proximal ulnar and radius (arrow).

  • Fig. 3. Examination of synovial fluid under polarized microscopy shows rhomboid crystals with weakly positive birefringence (wet smear, compensator axis: A, x400, B, x1,000).


Cited by  1 articles

A Case of Calcium Pyrophosphate Dihydrate Deposition Disease Associated with Primary Hyperparathyroidism
Chang-Nam Son, Ji-Young Lee, Dam Kim, Kyung-Bin Joo, Seunghun Lee, Young-Soo Song, Dong-Sun Kim, Kyung Tae, Tae-Seok Yoo, Jae-Bum Jun
J Rheum Dis. 2014;21(2):82-86.    doi: 10.4078/jrd.2014.21.2.82.


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