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Stimulatory Effect of beta-glucans on Immune Cells

Kim HS, Hong JT, Kim Y, Han SB

beta-Glucans are naturally occurring polysaccharides that are produced by bacteria, yeast, fungi, and many plants. Although their pharmacological activities, such as immunomodulatory, anti-infective and anti-cancer effects, have been well studied,...
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Immunomodulatory effect of beta-glucan derived from Saccharomyces cerevisiae strains

Lee YO, Shin MS, Lee WK

  • KMID: 2055092
  • J Biomed Res.
  • 2013 Mar;14(1):23-27.
The aim of this study was to evaluate immunopotentiating activities of beta-glucan derived from Saccharomyces (S.) cerevisiae and to select new strains having possibility as an immune-enhancing substance. We examined...
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Determination of Glucan Contents in the Fruiting Bodies and Mycelia of Lentinula edodes Cultivars

Bak WC, Park JH, Park YA, Ka KH

Shiitake mushrooms (Lentinula edodes) containing beta-glucans may be beneficial for human health; they have been used in the treatment of cancer, hypertension, and high cholesterol levels. The objective of this...
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Potentiation of Innate Immunity by beta-Glucans

Seong SK, Kim HW

  • KMID: 2312582
  • Mycobiology.
  • 2010 Jun;38(2):144-148.
beta-Glucans have been known to exhibit antitumor activities by potentiating host immunity by an unknown mechanism. The C-type lectin dectin-1, a beta-glucan receptor, is found on the macrophage and can...
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Biomedical Issues of Dietary fiber beta-Glucan

Kim SY, Song HJ, Lee YY, Cho KH, Roh YK

beta-Glucan is a polysaccharide in the form of fiber and the main element of fiber in grains such as barley, oats, yeast and mushrooms. Many studies have examined the efficacy...
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Evaluation of the Protective Effect of Beta Glucan on Amikacin Ototoxicity Using Distortion Product Otoacoustic Emission Measurements in Rats

Bayindir T, Filiz A, Iraz M, Kaya S, Tan M, Kalcioglu

  • KMID: 2278513
  • Clin Exp Otorhinolaryngol.
  • 2013 Mar;6(1):1-6.
OBJECTIVES: This experimental study investigated the possible protective effect of beta glucans on amikacin ototoxicity. METHODS: Thirty-eight rats with normal distortion product otoacoustic emissions (DPOAEs) were divided into four groups. Group...
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Deletion of GBG1/AYR1 Alters Cell Wall Biogenesis in Saccharomyces cerevisiae

Ahn KW, Kim SW, Kang HG, Kim KH, Park YH, Choi WJ, Park HM

  • KMID: 2312574
  • Mycobiology.
  • 2010 Jun;38(2):102-107.
We identified a gene for beta-1,3-glucan synthesis (GBG1), a nonessential gene whose disruption alters cell wall synthesis enzyme activities and cell wall composition. This gene was cloned by functional complementation...
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Beta-glucan for Glycemic Control Effects in Adults: a Meta-analysis

Hwang GS, Roh YK, Song HJ, Lee YY, Kim HJ, Hwang IH, Kim SY, Cho HM

  • KMID: 2294426
  • J Korean Acad Fam Med.
  • 2008 Jul;29(7):475-483.
BACKGROUND: Recently, there has been an increase of emerging concerns between dietary fiber and diabetics. Increasing intake of dietary fiber leads to delaying absorption of glucose, and lowering of serum...
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Binding Specificity of Philyra pisum Lectin to Pathogen-Associated Molecular Patterns, and Its Secondary Structure

Park BT, Kim BS, Park H, Jeong J, Hyun H, Hwang HS, Kim HH

We recently reported a Philyra pisum lectin (PPL) that exerts mitogenic effects on human lymphocytes, and its molecular characterization. The present study provides a more detailed characterization of PPL based...
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A novel beta-glucan produced by Paenibacillus polymyxa JB115 induces nitric oxide production in RAW264.7 macrophages

Chang ZQ, Lee JS, Hwang MH, Hong JH, Jung HK, Lee SP, Park SC

The effect of extracellular beta-(1-->3), (1-->6)-glucan, produced by Paenibacillus polymyxa JB115, on nitric oxide (NO) production in RAW264.7 macrophages was investigated. beta-glucan induced the production of NO by RAW264.7 macrophages...
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Maturation of bone marrow-derived dendritic cells by a novel beta-glucan purified from Paenibacillus polymyxa JB115

Ko EJ, Byon YY, Jee Y, Shin T, Park SC, Hahn TW, Joo HG

We investigated the immunostimulatory effects of a novel beta-glucan purified from Paenibacillus (P.) polymyxa JB115 on bone marrow-derived dendritic cells (DCs), a type of potent antigen-presenting cells. beta-glucan isolated from...
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