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Gene therapy of scarring: a lesson learned from fetal scarless wound healing

Liu W, Cao Y, Longaker M

Cutaneous wounding in adult humans and higher vertebrate animals results in scar formation. In contrast, both human and animal fetuses, at early gestational ages, exhibit skin wound healing without scarring....
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Cellular signaling in tissue regeneration

Kim WJ

With recent progress in stem cell-based research, there has been tremendous interest in stem cell-based tissue regeneration. Stem cells can be differentiated into specialized cells/tissues by growth factors and cytokines....
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miR-379 Inhibits Cell Proliferation, Invasion, and Migration of Vascular Smooth Muscle Cells by Targeting Insulin-Like Factor-1

Li K, Wang Y, Zhang A, Liu B, Jia L

PURPOSE: MicroRNAs are small non-coding RNAs that play important roles in vascular smooth muscle cell (VSMC) function. This study investigated the role of miR-379 on proliferation, invasion, and migration of...
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Comparison of three skin-stretching devices for closing skin defects on the limbs of dogs

Tsioli V, Papazoglou LG, Papaioannou N, Psalla D, Savvas I, Pavlidis L, Karayannopoulpou M

Our objective was to evaluate the effectiveness of skin-stretching devices for closing defects on the extremities of dogs. Antebrachial skin defects were created on the limbs of 24 dogs randomly...
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Implantation of canine umbilical cord blood-derived mesenchymal stem cells mixed with beta-tricalcium phosphate enhances osteogenesis in bone defect model dogs

Jang BJ, Byeon YE, Lim JH, Ryu HH, Kim WH, Koyama Y, Kikuchi M, Kang KS, Kweon OK

This study was performed to evaluate the osteogenic effect of allogenic canine umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) mixed with beta-tricalcium phosphate (beta-TCP) in orthotopic implantation. Seven hundred milligrams of...
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Two-year follow-up of eyes without topical corticosteroid treatment after photorefractive keratectomy (PRK)

Choi SY, Kim HY, Kim JY, Wee WR, Lee JH

This study was performed to evaluate the result of photorefractive keratectomy (PRK) without topical corticosteroid treatment at postoperative two years. PRK was performed by Summit OmniMed excimer laser, using a...
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Snakebite in Korea: A Guideline to Primary Surgical Management

Rha JH, Kwon SM, Oh JR, Han BK, Lee KH, Kim JH

PURPOSE: Snakebite is an emergency which causes local symptoms such as pain and edema around the bite. Systemic symptoms may also develop, such as dizziness or renal failure, and may...
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Guided bone regeneration with beta-tricalcium phosphate and poly Llactide-co-glycolide-co-epsilon-caprolactone membrane in partial defects of canine humerus

Oh T, Rahman MM, Lim JH, Park MS, Kim DY, Yoon JH, Kim WH, Kikuchi M, Tanaka J, Koyama Y, Kweon OK

This study was performed to evaluate the effect of betatricalcium phosphate and poly L-lactide-co-glycolide-coepsilon- caprolactone (TCP/PLGC) membrane in the repair of partial bone defects in canine proximal humerus. Three adult...
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