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Inhibition of hepatitis B virus replication by RNA interference

Park YG

No abstract available.
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Intracellular Antibody Fragment Against Hepatitis B Virus X Protein Does Not Inhibit Viral Replication

Jin YH, Hong SH, Kim K, Shin HJ, Park S

Replication of the hepatitis B virus is suppressed by deficiency of the X protein. Although several molecules that block cellular targets of X protein reduce the production of hepatitis B...
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Advancement in in vitro Culture System of Hepatitis C Virus Replication

Kim DG

  • KMID: 1767626
  • Korean J Gastroenterol.
  • 2008 Sep;52(3):196-199.
No abstract available.
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Quantitative measurement of influenza virus replication using consecutive bronchoalveolar lavage in the lower respiratory tract of a ferret model

Lee DH, Kim JI, Lee JW, Chung WH, Park JK, Lee YN, Han JS, Kim HY, Lee SW, Song CS

The ferret is an established animal model of influenza virus infection. Although viral replication in the upper respiratory tract is usually measured with consecutively collected nasal washes, daily evaluation of...
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Differences in the patterns and outcomes of enhanced viral replication between hepatitis C virus and hepatitis B virus in patients with hepatocellular carcinoma during transarterial chemolipiodolization

Sung PS, Bae SH, Jang JW, Song DS, Kim HY, Yoo SH, Park CH, Kwon JH, Song MJ, You CR, Choi JY, Yoon SK

BACKGROUND/AIMS: Enhanced replication of hepatitis C virus (HCV) is well described in the setting of moderate to severe immunosuppression. The aims of this retrospective study were to determine the incidence...
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Impact of Nucleotide Mutations at the HNF3- and HNF4-Binding Sites in Enhancer 1 on Viral Replication in Patients with Chronic Hepatitis B Virus Infection

Cho EY, Kim HJ, Park C, So HS, Park RK, Kim HC

  • KMID: 1806674
  • Gut Liver.
  • 2013 Sep;7(5):569-575.
BACKGROUND/AIMS: The hepatitis B virus (HBV) genome contains binding sites for hepatocyte nuclear factors (HNF) 3 and 4 in the core domain of enhancer 1 (Enh1), and mutations in this...
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Functional analysis of prv-miR-LLT11a encoded by pseudorabies virus

Liu H, Yang L, Shi Z, Lv R, Yang X, Wang C, Chen L, Chang H

Viral-encoded microRNAs (miRNAs) have vital roles in the regulation of virus replications and host immune responses. The results of previous studies have indicated that miRNA clusters are involved in the...
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Development of a packaging cell line for propagation of replication-deficient adenovirus vector

Kim JS, Lee SH, Cho YS, Park KS, Kim YH, Lee JH

  • KMID: 938878
  • Exp Mol Med.
  • 2001 Sep;33(3):145-149.
A human embryonic kidney cell line 293 is widely used for adenovirus production and propagation. With this cell line, however, replication-competent virus (RCV) is frequently generated, especially during large-scale production...
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Human Immunodeficiency Virus Type 1 Tat-Mediated Cellular Response in Myeloid Cells

Kim NY, Kim YW

Human immunodeficiency virus type 1 (HIV-1)-infected cells respond to the infection with different outcomes depending on their cell type. The interplay of cellular and viral proteins is a key player...
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Inhibition of in vitro hepatitis B virus replication by lentivirus-mediated short-hairpin RNA against HBx

Kim JW, Lee SH, Park YS, Jeong SH, Kim N, Lee DH

BACKGROUNDS/AIMS: Hepatitis B virus (HBV) replicates via RNA intermediates, which could serve as targets for RNA interference (RNAi). Vector-mediated short-hairpin RNA (shRNA) can induce sustained RNAi in comparison to small...
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Hepatitis C virus: virology and life cycle

Kim CW, Chang KM

Hepatitis C virus (HCV) is a positive sense, single-stranded RNA virus in the Flaviviridae family. It causes acute hepatitis with a high propensity for chronic infection. Chronic HCV infection can...
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Viscerotropic velogenic Newcastle disease virus replication in feathers of infected chickens

Lee DH, Kwon JH, Noh JY, Park JK, Yuk SS, Erdene-Ochir TO, Nahm SS, Kwon YK, Lee SW, Song CS

Newcastle disease viruses (NDVs) cause systemic diseases in chickens with high mortality. However, little is known about persistence of NDVs in contaminated tissues from infected birds. In this study, we...
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Inhibition of HBV replication by antisense oligodeoxyribonucleotides in HepG2 cells transfected with a cloned HBV DNA

Oh SH, Yeh BI, Kim SH

The effect of antisense oligodeoxyribonucleotides(oligo[dN]s) on hepatitis B virus(HBV) replication in HepG2 cells harboring a cloned HBV genome was examined. Antisense oligo(dN)s directed at translational initiation sites of S, pre...
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Phospholipase A2 isolated from the venom of honey bees prevents viral attachment in mammalian cells

Hewawaduge CY, Lee BH, Kim TH, Uddin MB, Kim JH, Kim CG, Lee JS

The belief that honey bee venom (BV) can be used to treat certain immune-related diseases, such as arthritis and rheumatic conditions, goes back to antiquity. A growing number of reports...
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Tumor - specific Virus Replication and Cytotoxicity of E1B 55 kD - deleted Adenovirus

Kim J, Lee B, Kim J, Ahn JB, Park JO, Yoo NC, Kim JH, Roh JK, Min JS, Kim BS, Lee H

  • KMID: 2137127
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):200-209.
PURPOSE: To overcome the limitations of cancer gene therapy using replication-incom- petent adenovirus, we generated E1B 55 kD-deleted adenovirus (YKL-1) by polymerase chain reaction (PCR) and homologous recombination. We then investigated tumor-specific virus replication...
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Associations of Expressions of HBcAg and HBsAg with the Histologic Activity of Liver Disease and Viral Replication

Son MS, Yoo JH, Kwon CI, Ko KH, Hong SP, Hwang SG, Park PW, Park CK, Rim KS

  • KMID: 2053358
  • Gut Liver.
  • 2008 Dec;2(3):166-173.
BACKGROUND/AIMS: Subcellular localization of hepatitis B virus (HBV) core antigen (HBcAg) and HBV surface antigen (HBsAg) is known to be related to the activity of liver disease and the level...
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The Role of Serum HBV-RNA Levels as a Marker of Intrahepatic Viral and Histologic Activity

Kwon JH

No abstract available.
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Effect of aldosterone on the amplification of oncolytic vaccinia virus in human cancer lines

Lee HJ, Rho J, Gui SR, Kim MK, Lee YK, Lee YS, Kim JE, Cho E, Cho M, Hwang TH

BACKGROUND/AIMS: JX-594 is an oncolytic virus derived from the Wyeth vaccinia strain that causes replication-dependent cytolysis and antitumor immunity. Starting with a cross-examination of clinical-trial samples from advanced hepatocellular carcinoma...
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Hepatitis B virus genetic diversity and mutant

Yim HJ

Hepatitis B virus (HBV) is a partially double stranded DNA virus with genetic diversity represented by eight genotypes (A to H). Natural course and response to treatment could be affected...
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Infectivity of basal epithelial cells in herpetic dendritic epithelial keratitis

Kim JH, Ko MK, Shin JC

In patients with herpes virus dendritic epithelial keratitis, the pathologic morphogenesis of the dendritic lesion was investigated by means of impression cytology. Impression specimens were taken from the lesions of...
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