- Effect of vigabatrin in pediatric intractable epilepsy
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Kim HD, Coe CJ
- KMID: 1684844
- J Korean Child Neurol Soc.
- 1993 Sep;1(1):148-157.
No abstract available. -
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- The clinical effect of vigabatrin in refractory pediatric epilepsies
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Kim KJ, Lee BH, Hwang SH, Hwang YS
- KMID: 1684861
- J Korean Child Neurol Soc.
- 1993 Dec;1(2):91-96.
No abstract available. -
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- Vigabatrin-Induced Multifocal Action Myoclonus in a Patient with Partial Epilepsy
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Lee SA, Jeong JP, Kang JK
- KMID: 1816454
- J Korean Epilepsy Soc.
- 1999 Dec;3(2):206-208.
Vigabatrin-induced myoclonus is rarely described in adult with partial epilepsy, We report vigavatrin-induced mulrifocal action myoclonus in a 34 year-old female with symptomatic partial epilepsy. Hwe seizures were resistant to... -
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- Visual Field Changes in Children with Vigabatrin Treatment
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Baek SC, Cho MS, Lee JH
- KMID: 2125574
- J Korean Ophthalmol Soc.
- 2003 Jul;44(7):1600-1606.
PURPOSE: Recently, several reports have documented persistent visual field changes associated with long-term use of Vigabatrin, an antiepileptic drug. Epilepsy is a common disease in children, therefore we investigated perimetric... -
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- Effects of Vigabatrin on Pilocarpine-Induced Seizures in Immature Rats
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Choe BR, Lee IG, Whang KT
- KMID: 2335517
- J Korean Pediatr Soc.
- 2001 Feb;44(2):185-192.
PURPOSE: Vigabatrin is a widely used antiepileptic drug that greatly increases whole brain gamma- aminobutyric acid(GABA). But little is known about the anticonvulsant effect of vigabatrin on pilocarpine-induced seizures in... -
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- Visual Field Changes in Pediatric and Adolescent Patients Treated with Vigabatrin
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Kim C, Kim JH, Choung HK, Kim SJ, Yu YS
- KMID: 2210854
- J Korean Ophthalmol Soc.
- 2007 Apr;48(4):547-554.
PURPOSE: To investigate perimetric changes in pediatric and adolescent patients treated with vigabatrin and to assess the relationship between the visual field defect and the cumulative dose, the duration of... -
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- A Clinical Study on Infantile Spasms with Vigabatrin Therapy
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Oh SJ, Park SG, Kang HH, Chung SJ
- KMID: 2104463
- J Korean Pediatr Soc.
- 1999 Feb;42(2):233-238.
PURPOSE: Infantile spasms are considered an age-specific and malignant epilepsy. It is not controlled easily by general anticonvulsants. Therefore, this study aimed to assess vigabatrin(VGT) efficacy in infantile spasms. METHODS: From... -
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- Comparative Add-on Trial of Vigabatrin and Valproic Acid on Intractable Partial Seizures with Carbamazepine Monotherapy
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Lee SK, Nam HW, Chang IJ
- KMID: 2016243
- J Korean Neurol Assoc.
- 1997 Aug;15(4):754-761.
PURPOSE: To evaluate the efficacy of vigabatrin and valproic acid add-on therapy in the treatment of uncontrolled partial-onset seizures through randomized active controlled parallel-group trial. METHODS: Criteria for entry included... -
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- Epilepsy in Children and Vigabatrin: Experiences in the USA
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Shields WD
- KMID: 2329223
- J Korean Child Neurol Soc.
- 1997 Oct;5(1):180-180.
Many children with epilepsy remain medically intractable inspire of the best available therapies. One of the most difficult seizure types to treat is infantile spasms. Many children will respond to... -
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- Visual Field Defect in the Vigabatrin-treated Pediatric Patients
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Kim JS, Lee SL
- KMID: 2137164
- J Korean Child Neurol Soc.
- 2001 May;9(1):80-85.
PURPOSE: Vigabatrin has proved to be a successful and well tolerated drug used for the treatment of epilepsy of partial onset and for infantile spasms(West's syndrome). It is a selective... -
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- Efficacy and Safety of Vigabatrin in Refractory Epilepsy
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Lee KS, Kim BS, Chung JB, Han SI, Yang DW, Chung SW
- KMID: 2065959
- J Korean Neurol Assoc.
- 1993 Mar;11(1):99-104.
Vigabatrin (gamma vinyl GABA) was used in an open study of add-on therapy in adult patients with refractory epilepsy. Sixteen chronic epileptic patients (9 males and 7 females) with eight... -
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- Assessment of the Relationship between Vigabatrin and Visual Field Defect in Children
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Chung SJ, Chung YH, Cho EH
- KMID: 2207104
- J Korean Pediatr Soc.
- 2002 Dec;45(12):1546-1550.
PURPOSE: The authors carried out this study to determine the relationship between vigabatrin (VGB) and visual field defect. METHODS: Seventy eight patients older than 8 years who had epilepsy which had... -
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- Study of Clinical Course of Epilepsy in Children with Tuberous Sclerosis Complex
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Lee EH, Jeong MH, Ko TS
- KMID: 2008755
- J Korean Epilepsy Soc.
- 2009 Dec;13(2):58-64.
PURPOSE: The aim of this study is to investigate the incidence, clinical features and outcome in pediatric tuberous sclerosis complex(TSC) patients with epilepsy. METHODS: Fifty seven of 74 patients (77.0%) were... -
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- Reconsideration of Vigabatrin Effect in Infantile Spasms Treatment
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Yoon DH, Moon JU, Lee JY, Lee IG
- KMID: 2453791
- Ann Child Neurol.
- 2019 Jun;27(2):51-56.
- doi: 10.26815/acn.2019.00094
PURPOSE: To investigate the effect of vigabatrin (VGB) as a therapeutic agent for patients with infantile spasms (IS), compare risk factors for treatment response, and review safety of VGB by... -
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- Epileptic Spasms, a Journey to Find Therapeutics Based on Pathophysiology
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Yum MS
- KMID: 2392545
- J Korean Child Neurol Soc.
- 2017 Sep;25(3):113-120.
- doi: 10.26815/jkcns.2017.25.3.113
After the first description of infantile spasms (IS) in 1841, extensive clinical and laboratory investigations have been done to find the pathophysiology and the optimal treatments. The concept of the... -
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- Open Clinical Trial of Vigabatrin as Add-on Therapy in Severely Intractable Partial Seizures
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Lee BI, Huh K, Kim JS, Park SC, Sung KM, Oh KJ
- KMID: 2065958
- J Korean Neurol Assoc.
- 1993 Mar;11(1):85-98.
Open clinical trial of vigabatrin (VG) as add-on therapy was conducted in 32 patients with severely medically intractable partial seizures with or without secondarily generalized tonic-clonic seizures. Study protocol consisted... -
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- A Case of Atypical Benign Partial Childhood Epilepsy
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Park HJ, Seol IJ
- KMID: 2335521
- J Korean Pediatr Soc.
- 2001 Feb;44(2):211-215.
We report a case of atypical benign partial childhood epilepsy in a 11 years old male child whose case has been followed up for 6 years. His first symptom was... -
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- Factors Related to Weight Changes in Epileptic Children Treated with Vigabatrin
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Bae SN, Choi BS, Nam SO, Park HJ
- KMID: 1829879
- J Korean Pediatr Soc.
- 2001 Nov;44(11):1269-1277.
PURPOSE: This study was undertaken to investigate factors related to weight changes in children treated with vigabatrin(VGB). METHODS: We have analyzed mean weight standard deviation scores(SDS) retrospectively and interviewed 35... -
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- A Case of Vigabatrin Induced Symptomatic Visual Field Defect
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Um KY, Kim SM, Lee BJ, Song HK, Kwon KH, Lee BC, Oh JS, Lee KH
- KMID: 2186055
- J Korean Neurol Assoc.
- 2000 Mar;18(2):232-234.
Vigabatrin (VGB) is one of the most frequently prescribed new anti-epileptic drugs in the world since 1989. It has minimal side effects and fewer drug interactions with other anti-epileptic drugs.... -
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- Gelastic Seizures in a Patient with Tuberous Sclerosis
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Kim SH, Kim K, Min JW, Yoo BG, Yoo KM
- KMID: 2333398
- J Korean Epilepsy Soc.
- 2002 Dec;6(2):150-153.
BACKGROUND: Gelastic seizures are characterized by ictal inappropriate sudden laughter as the predominant seizure manifestation. they are very rare and may occur in patients with hypothalamic hamartomas, pituitary tumors, astrocytomas... -
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