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Interferon consensus sequence binding protein: Not essential for interferon alpha-mediated antiviral response to vesicular-stomatitis virus infection in HL-60 cells

Park BK

BACKGROUND: The role of the interferon consensus sequence binding protein (ICSBP), a member of interferon regulatory factor family, in protecting against a vesicular stomatitis virus (VSV) infection has not been...
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The Efficiency of the Vesicular Stomatis G Envelope in Transduction into Hematopoietic Stem Cell

Park JY, Yoo ES

OBJECTIVES: Stable gene transfer to human pluripotent hematopoietic stem cells is an attractive strategy for the curative treatment of many genetic hematologic disorders. In clinical tral, the level of gene...
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Cell Death Mechanisms in Esophageal Squamous Cell Carcinoma Induced by Vesicular Stomatitis Virus Matrix Protein

Douzandegan Y, Tahamtan A, Gray Z, Nikoo HR, Tabarraei , Moradi A

OBJECTIVES: Vesicular stomatitis virus (VSV) is under development as an oncolytic virus due to its preferential replication in cancer cells and oncolytic activity, however the viral components responsible have not...
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The Role of Noncoding Region in Hantaan Viral S Genome for Expression of Nucleocapsid Protein

Yu CH, Lee YS, Lee HD, Park C, Park KY, Lee PW

  • KMID: 1896561
  • J Korean Soc Virol.
  • 2000 Mar;30(1):39-49.
The genome of Hantaan virus, the prototype of the hantavirus genus, is composed of three segmented, single stranded negative sense RNA genome. The 5' and 3' termini of the Hantaan...
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Vesicular Stomatitis Virus G Glycoprotein and ATRA Enhanced Bystander Killing of Chemoresistant Leukemic Cells by Herpes Simplex Virus Thymidine Kinase/Ganciclovir

Hu C, Chen Z, Zhao W, Wei L, Zheng Y, He C, Zeng Y, Yin B

  • KMID: 2170650
  • Biomol Ther.
  • 2014 Mar;22(2):114-121.
Refractoriness of acute myeloid leukemia (AML) cells to chemotherapeutics represents a major clinical barrier. Suicide gene therapy for cancer has been attractive but with limited clinical efficacy. In this study,...
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The Effect of Recombinant Baculovirus (BacG-CMV-P53) Mediated Gene Therapy in the HT-1376 Bladder Cancer Cell Line

Suh HJ, Lee DH, Lee JY, Paik SY

  • KMID: 2293259
  • Korean J Urol.
  • 2004 Nov;45(11):1156-1161.
PURPOSE: In preliminary studies, it was found that mammalian cells can be infected by recombinant baculovirus in vitro. Therefore, the potential use of recombinant baculovirus(BacG-cytonegalovirus(CMV)-P53) for the bladder gene therapy...
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Ribosomal Protein L19 and L22 Modulate TLR3 Signaling

Yang EJ, Seo JW, Choi IH

BACKGROUND: Toll-like receptor 3 (TLR3) recognizes double-stranded RNA (dsRNA) and induces inflammation. In this study we attempted to ascertain if there are endogenous host molecules controlling the production of cytokines...
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Phospholipase A2 isolated from the venom of honey bees prevents viral attachment in mammalian cells

Hewawaduge CY, Lee BH, Kim TH, Uddin MB, Kim JH, Kim CG, Lee JS

The belief that honey bee venom (BV) can be used to treat certain immune-related diseases, such as arthritis and rheumatic conditions, goes back to antiquity. A growing number of reports...
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Species Specific Antiviral Activity of Porcine Interferon-α8 (IFNα8)

Kim E, Jhun H, Kim J, Park U, Jo S, Kwak A, Kim S, Nguyen TT, Kang Y, Choi I, Lee J, Kim H, Kim Y, Lee S, Kim S

Interferons (IFNs) have been known as antiviral genes and they are classified by type 1, type 2, and type 3 IFN. The type 1 IFN consists of IFNα, IFNβ, IFNτ,...
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