- Zerumbone, Sesquiterpene Photochemical from Ginger, Inhibits Angiogenesis
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Park JH, Park GM, Kim JK
- KMID: 2285576
- Korean J Physiol Pharmacol.
- 2015 Jul;19(4):335-340.
- doi: 10.4196/kjpp.2015.19.4.335
Here, we investigated the role of zerumbone, a natural cyclic sesquiterpene of Zingiber zerumbet Smith, on angiogenesis using human umbilical vein endothelial cells (HUVECs). Zerumbone inhibited HUVECs proliferation, migration and... -
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- Expression of Vascular Endothelial Growth Factor-C in Breast Carcinoma
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Chung MJ, Yang SH, Jang KY, Moon WS, Kang MJ, Lee DG
- KMID: 2073754
- Korean J Pathol.
- 2005 Dec;39(6):401-405.
BACKGROUND: Vascular endothelial growth factor-C (VEGF-C) is a novel growth factor that regulates lymphangiogenesis and/or angiogenesis via binding to the vascular endothelial growth factor receptor-3 (VEGFR-3) or VEGFR-2. Recent... -
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- Angiokeratoma circumscriptum of the buccal mucosa: a case report and literature review
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Kang YH, Byun JH, Park BW
- KMID: 2005454
- J Korean Assoc Oral Maxillofac Surg.
- 2014 Oct;40(5):240-245.
- doi: 10.5125/jkaoms.2014.40.5.240
Angiokeratoma is a benign cutaneous lesion of the capillaries, presenting as dilated vessels in the upper part of the dermis. Although this disorder is classified into various types and has... -
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- Targeting Receptor Tyrosine Kinase on Endothelial Cells in an Orthotopic Tumor Model of Oral Squamous Cell Carcinorma
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Park YW, Kim SH
- KMID: 2328427
- J Korean Assoc Oral Maxillofac Surg.
- 2009 Apr;35(2):55-65.
PURPOSE: We determined the therapeutic effects of blockade of epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF) receptor tyrosine kinases on the growth of oral squamous cell carcinoma... -
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- Cellular and molecular characterization of adenoid cystic carcinoma of the salivary glands
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Park YW
- KMID: 2183812
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2005 Mar;27(2):110-122.
Adenoid cystic carcinoma (ACC) of salivary glands has a protracted clinical course with perineural invasion, delayed onset of hematogenous metastasis, and poor responses to classical cytotoxic chemotherapic agents. Most... -
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- Effect of Anti-vascular Endothelial Growth Factor Antibody on the Survival of Cultured Retinal Ganglion Cells
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Lee JM, Bae HW, Lee SY, Seong GJ, Kim CY
- KMID: 2385586
- Korean J Ophthalmol.
- 2017 Aug;31(4):360-365.
- doi: 10.3341/kjo.2017.0054
PURPOSE: To investigate the effects of anti-vascular endothelial growth factor (VEGF) antibody on the survival of retinal ganglion cell (RGC)-5 cells differentiated with staurosporine under oxidative stress. METHODS: We used real-time... -
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- Concomitant inhibition of epidermal growth factor and vascular endothelial growth factor receptor tyrosine kinases in oral squamous cell carcinoma
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Park YW, Lee SS
- KMID: 1960517
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2006 May;28(3):193-201.
Squamous cell carcinoma(SCC) of head and neck(SCCHN) is the sixth most common human malignant tumor. However, despite advances in prevention and treatment of SCC, the five-year survival rates for patients... -
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- Differences in Expression of VEGF-A, VEGFR-1, VEGFR-2 and Microvessel Density in Colorectal Cancer with Liver Metastasis
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Jeong EH, Kim Y, Min BW, Lee KH, Kim HS, Lee JH
- KMID: 2277533
- Korean J Pathol.
- 2010 Dec;44(6):571-580.
BACKGROUND: Colorectal cancer (CRC) is one of the most common malignant neoplasms and is a leading cause of mortality worldwide. Metastasis to the liver is a frequent event in patients... -
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- Inhibition of Lymphatic Endothelial Growth Factor Receptor in a Murine Model of Oral Squamous Cell Carcinoma
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Kye JY, Park YW
- KMID: 2136910
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2011 Jan;33(1):1-9.
PURPOSE: Tumor associated angiogenesis and/or lymphangiogenesis are known to be linked by VEGFR signaling pathways. These processes are regulated by several growth factors including VEGFR-2, VEGFR-3. E7080 is an orally... -
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- Circulating Endothelial Progenitor Cells and Vasculogenic Factors in Pterygium Pathogenesis
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Song YS, Lee JK, Kim JC
- KMID: 2110354
- J Korean Ophthalmol Soc.
- 2006 Sep;47(9):1472-1480.
PURPOSE: We investigated whether endothelial progenitor cells (EPCs) and vasculogenic factors are involved in the pathogenesis of pterygium and the mechanism underlying the selective recruitment of EPCs during this process. METHODS:... -
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- Radiation up-regulates the expression of VEGF in a canine oral melanoma cell line
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Flickinger I, Rutgen BC, Gerner W, Calice I, Tichy A, Saalmuller A, Kleiter M
- KMID: 1705523
- J Vet Sci.
- 2013 Jun;14(2):207-214.
- doi: 10.4142/jvs.2013.14.2.207
To evaluate radiosensitivity and the effects of radiation on the expression of vascular endothelial growth factor (VEGF) and VEGF receptors in the canine oral melanoma cell line, TLM 1, cells... -
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- Photosensitivity Reactions to Vandetanib: Redevelopment after Sequential Treatment with Docetaxel
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Son YM, Roh JY, Cho EK, Lee JR
- KMID: 2171860
- Ann Dermatol.
- 2011 Dec;23(Suppl 3):S314-S318.
- doi: 10.5021/ad.2011.23.S3.S314
Vandetanib (ZD6474, Zactima(TM)) is a novel, orally available inhibitor of different intracellular signaling pathways involved in tumor growth, progression, and angiogenesis, including vascular endothelial growth factor receptor-2, epidermal growth factor... -
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- Expressions of vascular metastasis related factors in murine orthotopic tumor models of salivary glands
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Jang JH, Kwon KJ, Park YW
- KMID: 2005055
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2007 Nov;29(6):499-508.
BACKGROUND AND PURPOSE: Some subtypes of malignant salivary gland tumors such as adenoid cystic carcinoma (ACC) frequently result in distant metastasis of vascular origin, which are main causes of treatment... -
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- Anti-Tumor Effects of Vascular Endothelial Growth Factor Inhibitor on Oral Squamous Cell Carcinoma Cell Lines
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Han SJ, Lee JH
- KMID: 2328428
- J Korean Assoc Oral Maxillofac Surg.
- 2009 Apr;35(2):66-73.
Tumor angiogenesis is a process leading to formation of blood vessels within tumors and is crucial for maintaining a supply of oxygen and nutrients to support tumor growth and... -
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- The Effect of Antipsychotic Drug Treatment on Serum VEGF, sVEGFR-1, and sVEGFR-2 Level in Schizophrenia: A Preliminary Study
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Kim TH, Kim DH, Lee SK, Son BK, Jung JS
- KMID: 2249324
- Korean J Biol Psychiatry.
- 2007 Nov;14(4):232-240.
OBJECTIVES: Vascular endothelial growth factor(VEGF), one of potent cytokines, and its receptors were related with various biological functions and pathological conditions. The purpose of this study was to investigate the... -
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- Comparative Evaluation for Potential Differentiation of Endothelial Progenitor Cells and Mesenchymal Stem Cells into Endothelial-Like Cells
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Sabry D, Noh O, Samir M
- KMID: 2164160
- Int J Stem Cells.
- 2016 May;9(1):44-52.
- doi: 10.15283/ijsc.2016.9.1.44
Understanding the mechanisms of vascular remodeling could lead to more effective treatments for ischemic conditions. We aimed to compare between the abilities of both human Wharton jelly derived mesenchymal stem... -
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- An experimental study for the detection of autocrine growth activity in the osteogenic cells after mandibular distraction osteogenesis
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Byun JH, Park BW, Park SC, Kim GC, Park BS, Kim JR
- KMID: 2043820
- J Korean Assoc Oral Maxillofac Surg.
- 2007 Aug;33(4):331-339.
BACKGROUND: Distraction osteogenesis (DO) is a useful method for treating cases demanding the generation of new bone. During DO, the angiogenic activity is crucial factor in the new bone formation.... -
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- Expression of vascular endothelial growth factor receptors in tumor and stromal cells of tongue squamous cell carcinoma
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Park BW, Byun JH, Hah YS, Kim DR, Chung IK, Kim JR, Kim UK, Park BS, Kim GC
- KMID: 2005234
- J Korean Assoc Oral Maxillofac Surg.
- 2007 Feb;33(1):11-19.
This study was to evaluate the expression of vascular endothelial growth factor receptors (VEGFRs) in tumor and stromal cells of tougue squamous cell carcinoma (SCC). We also wanted to characterize... -
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- Expression of Semaphorin 3A and Neuropilin 1 in Asthma
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Shim EJ, Chun E, Kang HR, Cho SH, Min KU, Park HW
- KMID: 1777678
- J Korean Med Sci.
- 2013 Oct;28(10):1435-1442.
- doi: 10.3346/jkms.2013.28.10.1435
Neuropilin 1 (NP1) is a part of essential receptor complexes mediating both semaphorin3A (SEMA3A) and vascular endothelial growth factor (VEGF) which is one of important mediators involved in the pathogenesis... -
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- Isomangiferin, a Novel Potent Vascular Endothelial Growth Factor Receptor 2 Kinase Inhibitor, Suppresses Breast Cancer Growth, Metastasis and Angiogenesis
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Wang B, Shen J, Wang Z, Liu J, Ning Z, Hu M
- KMID: 2441863
- J Breast Cancer.
- 2018 Mar;21(1):11-20.
- doi: 10.4048/jbc.2018.21.1.11
PURPOSE: Vascular endothelial growth factor (VEGF) signal transduction mainly depends on its binding to VEGF receptor 2 (VEGFR-2). VEGF downstream signaling proteins mediate several of its effects in cancer progression,... -
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