- The discovery of placenta growth factor and its biological activity
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De Falco S
- KMID: 1120136
- Exp Mol Med.
- 2012 Jan;44(1):1-9.
- doi: 10.3858/emm.2012.44.1.025
Angiogenesis is a complex biological phenomenon crucial for a correct embryonic development and for post-natal growth. In adult life, it is a tightly regulated process confined to the uterus and... -
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- Altered Cellular Kinetics in the Growth Plate of the Femoral Head of Spontaneously Hypertensive Rats
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Park H, Kong SY, Kim HW
- KMID: 1777000
- Yonsei Med J.
- 2012 May;53(3):625-633.
- doi: 10.3349/ymj.2012.53.3.625
PURPOSE: Pathologic changes in the growth plate remain unknown in Legg-Calve-Perthes (LCP) disease. Spontaneously hypertensive rats have proven to be a good model for studying LCP disease. This study investigated... -
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- Intravitreal Bevacizumab (Avastin) as an Adjuvant for the Treatment of Posterior Scleritis
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Lim JW, Park JH
- KMID: 1018419
- Korean J Ophthalmol.
- 2011 Aug;25(4):282-284.
- doi: 10.3341/kjo.2011.25.4.282
We report a case of posterior scleritis effectively managed with intravitreal bevacizumab. A 71-year-old woman was diagnosed with posterior scleritis. Although she was initially treated with systemic steroids, her clinical... -
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- A Case of Hypertrophic Osteoarthropathy Associated with Epithelioid Hemangioendothelioma
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Kim JH, Lee EB, Kim S, Kang HW, Suh JW, Yoon WJ, Kim SH, Kang EH, Im CH, Song YW, Lee HS
- KMID: 1786835
- J Korean Med Sci.
- 2004 Jun;19(3):484-486.
- doi: 10.3346/jkms.2004.19.3.484
Epithelioid hemangioendothelioma is a rare vascular tumor, which occurs in the lung, liver, bone, and soft tissue. Hypertrophic osteoarthropathy is a syndrome characterized by subperiosteal new bone formation, joint effusion... -
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- Chlorogenic Acid Decreases Retinal Vascular Hyperpermeability in Diabetic Rat Model
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Shin JY, Sohn J, Park KH
- KMID: 1786971
- J Korean Med Sci.
- 2013 Apr;28(4):608-613.
- doi: 10.3346/jkms.2013.28.4.608
To evaluate the effect of chlorogenic acid (CGA), a polyphenol abundant in coffee, on retinal vascular leakage in the rat model of diabetic retinopathy, Sprague-Dawley rats were divided into four... -
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- The Effect of Interleukin-4 and Amphiregulin on the Proliferation of Human Airway Smooth Muscle Cells and Cytokine Release
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Shim JY, Park SW, Kim DS, Shim JW, Jung HL, Park MS
- KMID: 1783073
- J Korean Med Sci.
- 2008 Oct;23(5):857-863.
- doi: 10.3346/jkms.2008.23.5.857
Airway smooth muscle (ASM) hyperplasia and angiogenesis are important features associated with airway remodeling. We investigated the effect of IL-4 and amphiregulin, an epidermal growth factor family member, on the... -
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- Identification of high-affinity VEGFR3-binding peptides through a phage-displayed random peptide library
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Shi LF, Wu Y, Li CY
- KMID: 2345924
- J Gynecol Oncol.
- 2015 Oct;26(4):327-335.
- doi: 10.3802/jgo.2015.26.4.327
OBJECTIVE: Vascular endothelial growth factor (VEGF) interaction with its receptor, VEGFR-3/Flt-4, regulates lymphangiogenesis. VEGFR-3/Flt-4 expression in cancer cells has been correlated with clinical stage, lymph node metastasis, and lymphatic invasion.... -
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- The Expression of Adiponectin Receptors and the Effects of Adiponectin and Leptin on Airway Smooth Muscle Cells
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Shin JH, Kim JH, Lee WY, Shim JY
- KMID: 2158199
- Yonsei Med J.
- 2008 Oct;49(5):804-810.
- doi: 10.3349/ymj.2008.49.5.804
PURPOSE: Obesity is a major risk factor for asthma and it influences airway smooth muscle function and responsiveness. Adiponectin is inversely associated with obesity and its action is mediated through... -
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- Effects of Diet-Induced Mild Obesity on Airway Hyperreactivity and Lung Inflammation in Mice
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Jung SH, Kwon JM, Shim JW, Kim DS, Jung HL, Park MS, Park SH, Lee J, Lee WY, Shim JY
- KMID: 1798140
- Yonsei Med J.
- 2013 Nov;54(6):1430-1437.
- doi: 10.3349/ymj.2013.54.6.1430
PURPOSE: Obesity has been suggested to be linked to asthma. However, it is not yet known whether obesity directly leads to airway hyperreactivity (AHR) or obesity-induced airway inflammation associated with... -
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- Therapeutic Effects of Topical Application of Ozone on Acute Cutaneous Wound Healing
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Kim HS, Noh SU, Han YW, Kim KM, Kang H, Kim HO, Park YM
- KMID: 1779150
- J Korean Med Sci.
- 2009 Jun;24(3):368-374.
- doi: 10.3346/jkms.2009.24.3.368
This study was undertaken to evaluate the therapeutic effects of topical ozonated olive oil on acute cutaneous wound healing in a guinea pig model and also to elucidate its therapeutic... -
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- Early Sustained Injections of Erythropoietin Improve Angiogenesis and Restoration of Perfusion in the Ischemic Mouse Hindlimb
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Ahn S, Min SK, Min SI, Suh JH, Kim SJ, Ha J
- KMID: 1782142
- J Korean Med Sci.
- 2012 Sep;27(9):1073-1078.
- doi: 10.3346/jkms.2012.27.9.1073
This study was conducted to investigate the effects of erythropoietin (Epo) on both acute and chronic limb ischemia (ALI and CLI) and to evaluate the differences in mechanisms according to... -
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- Differential Expression of Hypoxia Inducible Factor-1 alpha and Tumor Cell Proliferation Between Squamous Cell Carcinomas and Adenocarcinomas Among Operable Non-Small Cell Lung Carcinomas
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Lee CH, Lee MK, Kang CD, Kim YD, Park DY, Kim JY, Sol MY, Suh KS
- KMID: 2157622
- J Korean Med Sci.
- 2003 Apr;18(2):196-203.
- doi: 10.3346/jkms.2003.18.2.196
This study aimed to evaluate whether the elevated level of hypoxia-inducible factor-1 alpha (HIF-1 alpha) correlated with histologic types, angiogenesis, tumor cell proliferation, and clinical parameters in common non-small cell... -
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- The Effect of Treadmill Exercise on Ischemic Neuronal Injury in the Stroke Animal Model: Potentiation of Cerebral Vascular Integrity
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Kang KA, Seong H, Jin HB, Park J, Lee J, Jeon JY, Kim YJ
- KMID: 1754161
- J Korean Acad Nurs.
- 2011 Apr;41(2):197-203.
- doi: 10.4040/jkan.2011.41.2.197
PURPOSE: This study was done to identify whether pre-conditioning exercise has neuroprotective effects against cerebral ischemia, through enhance brain microvascular integrity. METHODS: Adult male Sprague-Dawley rats were randomly divided into four... -
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- Carcinoma ex Pleomorphic Adenoma of the Salivary Glands: Distinct Clinicopathologic Features and Immunoprofiles Between Subgroups According to Cellular Differentiation
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Kim JW, Kwon GY, Roh JL, Choi SH, Nam SY, Kim SY, Cho KJ
- KMID: 1785983
- J Korean Med Sci.
- 2011 Oct;26(10):1277-1285.
- doi: 10.3346/jkms.2011.26.10.1277
In carcinoma ex pleomorphic adenoma (CXPA), pleomorphic adenoma (PA) and diverse carcinoma components showing luminal (ductal) or non-luminal (myoepithelial) differentiation coexist. To elucidate the clinicopathological implications of cellular differentiation in... -
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- Effect of Small Hairpin RNA Targeting Endothelin-Converting Enzyme-1 in Monocrotaline-Induced Pulmonary Hypertensive Rats
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Son JS, Kim KC, Kim BK, Cho MS, Hong YM
- KMID: 2157974
- J Korean Med Sci.
- 2012 Dec;27(12):1507-1516.
- doi: 10.3346/jkms.2012.27.12.1507
The purpose of this study was to investigate the therapeutic effects of small hairpin RNA (shRNA) targeting endothelin-converting enzyme (ECE)-1 in monocrotaline (MCT)-induced pulmonary hypertensive rats. Ninty-four Sprague-Dawley rats were... -
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- COMP-Angiopoietin-1 Promotes Cavernous Angiogenesis in a Type 2 Diabetic Rat Model
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Kim SO, Lee HS, Ahn K, Park K
- KMID: 1777560
- J Korean Med Sci.
- 2013 May;28(5):725-730.
- doi: 10.3346/jkms.2013.28.5.725
Cartilage oligomeric matrix protein-angiopoietin-1 (COMP-Ang1) is an angiogenic factor for vascular angiogenesis. The aim was to investigate the effect of an intracavernosal injection of COMP-Ang1 on cavernosal angiogenesis in a... -
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- Modulation of Colon Cancer Cell Invasiveness Induced by Deoxycholic Acid
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Kim HS, Lee YK, Kim JW, Baik SK, Kwon SO, Jang HI
- KMID: 782732
- Korean J Gastroenterol.
- 2006 Jul;48(1):9-18.
BACKGROUND/AIMS: Deoxycholic acid (DCA), a secondary bile acid, has been implicated to promote colon cancer growth and progression. However, its molecular mechanisms are largely unknown. In this study, we investigated... -
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- Expression of PTEN and Its Correlation with Angiogenesis in Gastric Carcinoma
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Park GS, Joo YE, Kim HS, Choi SK, Rew JS, Park CS, Kim SJ
- KMID: 935211
- Korean J Gastroenterol.
- 2005 Sep;46(3):196-203.
BACKGROUND/AIMS: Phosphatase and tensin homolog deleted on chromosome ten (PTEN) is a recently clarified tumor suppressor gene located in 10q23.3. Alterations of this gene are associated with tumor progression and... -
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- Comparing the osteogenic potential of canine mesenchymal stem cells derived from adipose tissues, bone marrow, umbilical cord blood, and Wharton's jelly for treating bone defects
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Kang BJ, Ryu HH, Park SS, Koyama Y, Kikuchi M, Woo HM, Kim WH, Kweon OK
- KMID: 1389770
- J Vet Sci.
- 2012 Sep;13(3):299-310.
- doi: 10.4142/jvs.2012.13.3.299
Alternative sources of mesenchymal stem cells (MSCs) for replacing bone marrow (BM) have been extensively investigated in the field of bone tissue engineering. The purpose of this study was to... -
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- A novel thiol compound, N-acetylcysteine amide, attenuates allergic airway disease by regulating activation of NF-kappaB and hypoxia-inducible factor-1alpha
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Lee KS, Kim SR, Park HS, Park SJ, Min KH, Lee KY, Choe YH, Hong SH, Han HJ, Lee YR, Kim JS, Atlas D, Lee YC
- KMID: 1091070
- Exp Mol Med.
- 2007 Dec;39(6):756-768.
Reactive oxygen species (ROS) play an important role in the pathogenesis of airway inflammation and hyperresponsiveness. Recent studies have demonstrated that antioxidants are able to reduce airway inflammation and hyperreactivity... -
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