- Plant factory: new resource for the productivity and diversity of human and veterinary vaccines
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Shim BS, Hong KJ, Maharjan P, Choe S
- KMID: 2455086
- Clin Exp Vaccine Res.
- 2019 Jul;8(2):136-139.
- doi: 10.7774/cevr.2019.8.2.136
Vaccination is one of the most successful strategies to prevent diseases caused by pathogens. Although various expression systems including Escherichia coli, yeast, insect, and mammalian cells are currently used for... -
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- Introduction of Vaccinomics to Develop Personalized Vaccines in Light of Changes in the Usage of Hantaan Virus Vaccine (Hantavax®) in Korea
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Bae JM
- KMID: 2460208
- J Prev Med Public Health.
- 2019 Sep;52(5):277-280.
- doi: 10.3961/jpmph.19.018
The Ministry of Food and Drug Safety of Korea made an official announcement in March 2018 that the total number of inoculations of Hantaan virus vaccine (Hantavax®) would change from... -
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- Recent vaccine technology in industrial animals
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Kim H, Lee YK, Kang SC, Han BK, Choi KM
- KMID: 2152692
- Clin Exp Vaccine Res.
- 2016 Jan;5(1):12-18.
- doi: 10.7774/cevr.2016.5.1.12
Various new technologies have been applied for developing vaccines against various animal diseases. Virus-like particle (VLP) vaccine technology was used for manufacturing the porcine circovirus type 2 and RNA particle... -
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- Ideal Vaccination Strategy in Inflammatory Bowel Disease
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Lee CK
- KMID: 2373201
- Korean J Gastroenterol.
- 2015 Mar;65(3):159-164.
- doi: 10.4166/kjg.2015.65.3.159
Inflammatory bowel disease (IBD) is a long-standing disease that often requires long-term use of immunosuppressive agents including immunomodulators (such as azathioprine, 6-mercaptopurine and methotrexate) and tumor necrosis factor-alpha inhibitors (such... -
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- A Current Research Insight into Function and Development of Adjuvants
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Sohn ES, Son E, Pyo S
- KMID: 2167974
- Immune Netw.
- 2004 Sep;4(3):131-142.
- doi: 10.4110/in.2004.4.3.131
In recent years, adjuvants have received much attention because of the development of purified subunit and synthetic vaccines which are poor immunogens and require adjuvants to evoke the immune response.... -
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- Rhoptry antigens as Toxoplasma gondii vaccine target
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Foroutan M, Ghaffarifar F, Sharifi Z, Dalimi A, Jorjani O
- KMID: 2438956
- Clin Exp Vaccine Res.
- 2019 Jan;8(1):4-26.
- doi: 10.7774/cevr.2019.8.1.4
Toxoplasmosis is a cosmopolitan zoonotic infection, caused by a unicellular protozoan parasite known as Toxoplasma gondii that belongs to the phylum Apicomplexa. It is estimated that over one-third of the... -
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- A Single Center Analysis of the Positivity of Hepatitis B Antibody after Neonatal Vaccination Program in Korea
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Kim YJ, Li P, Hong JM, Ryu KH, Nam E, Chang MS
- KMID: 2375082
- J Korean Med Sci.
- 2017 May;32(5):810-816.
- doi: 10.3346/jkms.2017.32.5.810
The antibody to hepatitis B surface antigen (anti-HBs) seropositivity rate after 3 doses of hepatitis B virus (HBV) vaccination during infancy period is known to be higher than 90%. However,... -
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- A Novel Recombinant BCG Vaccine Encoding Eimeria tenella Rhomboid and Chicken IL-2 Induces Protective Immunity Against Coccidiosis
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Wang Q, Chen L, Li J, Zheng J, Cai N, Gong P, Li S, Li H, Zhang X
- KMID: 1792178
- Korean J Parasitol.
- 2014 Jun;52(3):251-256.
A novel recombinant Bacille Calmette-Guerin (rBCG) vaccine co-expressed Eimeria tenella rhomboid and cytokine chicken IL-2 (chIL-2) was constructed, and its efficacy against E. tenella challenge was observed. The rhomboid gene... -
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- Production and immunogenicity of chimeric virus-like particles containing the spike glycoprotein of infectious bronchitis virus
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Lv L, Li X, Liu G, Li R, Liu Q, Shen H, Wang W, Xue C, Cao Y
- KMID: 1784641
- J Vet Sci.
- 2014 Jun;15(2):209-216.
- doi: 10.4142/jvs.2014.15.2.209
Infectious bronchitis virus (IBV) poses a severe threat to the poultry industry and causes heavy economic losses worldwide. Vaccination is the most effective method of preventing infection and controlling the... -
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- Generation and Immunity Testing of a Recombinant Adenovirus Expressing NcSRS2-NcGRA7 Fusion Protein of Bovine Neospora caninum
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Jia LJ, Zhang SF, Qian NC, Xuan XN, Yu LZ, Zhang XM, Liu MM
- KMID: 1499707
- Korean J Parasitol.
- 2013 Apr;51(2):247-253.
- doi: 10.3347/kjp.2013.51.2.247
Neospora caninum is the etiologic agent of bovine neosporosis, which affects the reproductive performance of cattle worldwide. The transmembrane protein, NcSRS2, and dense-granule protein, NcGRA7, were identified as protective antigens... -
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- Marek's disease vaccine activates chicken macrophages
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Wang D, Sun S, Heidari M
- KMID: 2412128
- J Vet Sci.
- 2018 May;19(3):375-383.
- doi: 10.4142/jvs.2018.19.3.375
To provide insights into the role of innate immune responses in vaccine-mediated protection, we investigated the effect of Marek's disease (MD) vaccine, CVI988/Rispens, on the expression patterns of selected genes... -
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- Immunogenicity of recombinant Lactobacillus plantarum NC8 expressing goose parvovirus VP2 gene in BALB/c mice
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Liu YY, Yang WT, Shi SH, Li YJ, Zhao L, Shi CW, Zhou FY, Jiang YL, Hu JT, Gu W, Yang GL, Wang CF
- KMID: 2412568
- J Vet Sci.
- 2017 Jun;18(2):159-167.
- doi: 10.4142/jvs.2017.18.2.159
Goose parvovirus (GPV) continues to be a threat to goose farms and has significant economic effects on the production of geese. Current commercially available vaccines only rarely prevent GPV infection.... -
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- A novel M2e-multiple antigenic peptide providing heterologous protection in mice
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Wen F, Ma JH, Yu H, Yang FR, Huang M, Zhou YJ, Li ZJ, Wang XH, Li GX, Jiang YF, Tong W, Tong GZ
- KMID: 2363337
- J Vet Sci.
- 2016 Mar;17(1):71-78.
- doi: 10.4142/jvs.2016.17.1.71
Swine influenza viruses (SwIVs) cause considerable morbidity and mortality in domestic pigs, resulting in a significant economic burden. Moreover, pigs have been considered to be a possible mixing vessel in... -
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- Enhancing mucosal immunity in mice by recombinant adenovirus expressing major epitopes of porcine circovirus-2 capsid protein delivered with cytosine-phosphate-guanosine oligodeoxynucleotides
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Chang HT, He XY, Liu YF, Chen L, Guo QH, Yu QY, Zhao J, Wang XW, Yang X, Wang CQ
- KMID: 2155623
- J Vet Sci.
- 2014 Sep;15(3):399-407.
- doi: 10.4142/jvs.2014.15.3.399
A recombinant replication-defective adenovirus expressing the major epitopes of porcine circovirus-2 (PCV-2) capsid protein (rAd/Cap/518) was previously constructed and shown to induce mucosal immunity in mice following intranasal delivery. In... -
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- Comparison of the seroconversion rate after primary hepatitis B vaccination and after revaccination of non-responders in full-term infants according to mother's HBsAg seropositivity
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Kang JH, Moon JW, Kong SH, Hwang KS, Mok JS, Lee HJ
- KMID: 2280239
- Korean J Pediatr.
- 2008 Nov;51(11):1165-1171.
- doi: 10.3345/kjp.2008.51.11.1165
PURPOSE: This study aimed to identify the true extent of non-responsiveness in full-term infants born from HBsAg-negative or HBsAg-positive mothers and vaccinated against hepatitis B virus (HBV) at 0, 1,... -
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- Optimized clade 2.3.2.1c H5N1 recombinant-vaccine strains against highly pathogenic avian influenza
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Jang JW, Lee CY, Kim IH, Choi JG, Lee YJ, Yuk SS, Lee JH, Song CS, Kim JH, Kwon HJ
- KMID: 2412554
- J Vet Sci.
- 2017 Aug;18(S1):299-306.
- doi: 10.4142/jvs.2017.18.S1.299
A/Puerto Rico/8/34 (PR8)-derived recombinant viruses have been used for seasonal flu vaccines; however, they are insufficient for vaccines against some human-fatal H5N1 highly pathogenic avian influenza (HPAI) viruses (HPAIV) due... -
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- Histopathological Evaluation of the Efficacy for Plant-produced E2 Protein Vaccine against Classical Swine Fever Virus (CSFV) in Piglets
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Kim SY, Jung BK, Park GN, Kim HR, An DJ, Shon EJ, Chang KS
- KMID: 2468033
- J Bacteriol Virol.
- 2019 Sep;49(3):133-140.
- doi: 10.4167/jbv.2019.49.3.133
Classical swine fever (CSF), previously known as hog cholera, remains one of the most important swine-related contagious diseases worldwide. In order to eradicate classical swine fever virus (CSFV), it is... -
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- Construction of A Stable Full-Length cDNA Clone of Japanese Encephalitis Virus Strain SA14-14-2 Using Low Copy Number Plasmid
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Min KI, Kim YM, Choo MS, Baek SY, Kim JO, Ryu SR, Min BS, Kim Y, Park MK, Byeon WH, Hur SJ
- KMID: 1579128
- J Bacteriol Virol.
- 2004 Dec;34(4):339-353.
Recently the reverse genetics system contributed to the progresses in the investigation of positive-stranded RNA viruses. Here, we report the successful construction of a stable full-length infectious cDNA clone of... -
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- Protective and Anti-Pathology Effects of Sm Fructose-1,6-Bisphosphate Aldolase-Based DNA Vaccine against Schistosoma mansoni by Changing Route of Injection
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Saber M, Diab T, Hammam O, Karim A, Medhat A, Khela M, El-Dabaa E
- KMID: 1499693
- Korean J Parasitol.
- 2013 Apr;51(2):155-163.
- doi: 10.3347/kjp.2013.51.2.155
This study aimed to evaluate the efficacy of fructose-1,6-bis phosphate aldolase (SMALDO) DNA vaccination against Schistosoma mansoni infection using different routes of injection. The SMALDO has been cloned into the... -
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- Chimeric rabies glycoprotein with a transmembrane domain and cytoplasmic tail from Newcastle disease virus fusion protein incorporates into the Newcastle disease virion at reduced levels
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Yu GM, Zu SL, Zhou WW, Wang XJ, Shuai L, Wang XL, Ge JY, Bu ZG
- KMID: 2412560
- J Vet Sci.
- 2017 Aug;18(S1):351-359.
- doi: 10.4142/jvs.2017.18.S1.351
Rabies remains an important worldwide health problem. Newcastle disease virus (NDV) was developed as a vaccine vector in animals by using a reverse genetics approach. Previously, our group generated a... -
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