- Involvement of JNK-initiated p53 accumulation and phosphorylation of p53 in pseudolaric acid B induced cell death
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Gong X, Wang M, Tashiro SI, Onodera S, Ikejima T
- KMID: 1110127
- Exp Mol Med.
- 2006 Aug;38(4):428-434.
A terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL) assay was used to determine that apoptosis causes HeLa cell death induced by pseudolaric acid B. The c-Jun N-terminal kinase (JNK) inhibitor... -
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- Prognostic Significance of p53, mTOR, c-Met, IGF-1R, and HSP70 Overexpression after the Resection of Hepatocellular Carcinoma
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Kang GH, Lee BS, Lee ES, Kim SH, Lee HY, Kang DY
- KMID: 1774532
- Gut Liver.
- 2014 Jan;8(1):79-87.
BACKGROUND/AIMS: The current study examines the expression of molecular biomarkers in hepatocellular carcinoma (HCC) and whether these findings correlate with the clinicopathologic features of the disease and patient survival. METHODS: We... -
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- Clinicopathological Significance of Maspin Expression in Breast Cancer
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Lee MJ, Suh CH, Li ZH
- KMID: 1781841
- J Korean Med Sci.
- 2006 Apr;21(2):309-314.
- doi: 10.3346/jkms.2006.21.2.309
Maspin is a unique serine proteinase inhibitor that has tumor suppressor activity. It has been reported that maspin is expressed in normal human mammary epithelial cells and it is down-regulated... -
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- Establishment of Hepatocellular Cancer Induced Pluripotent Stem Cells Using a Reprogramming Technique
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Kim HJ, Jeong J, Park S, Jin YW, Lee SS, Lee SB, Choi D
- KMID: 2412193
- Gut Liver.
- 2017 Mar;11(2):261-269.
- doi: 10.5009/gnl15389
BACKGROUND/AIMS: Cancer is known to be a disease by many factors. However, specific results of reprogramming by pluripotency-related transcription factors remain to be scarcely reported. Here, we verified potential effects... -
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- Pro-apoptotic function of hepatitis B virus X protein
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Kim KH
- KMID: 1792589
- Korean J Hepatol.
- 2010 Jun;16(2):112-122.
- doi: 10.3350/kjhep.2010.16.2.112
Infection of hepatitis B virus (HBV) is a main cause of liver diseases including hepatitis, cirrhosis and hepatocellular carcinoma (HCC). Among the HBV-encoded proteins, the HBV X protein (HBx) has... -
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- Sonography of Invasive Apocrine Carcinoma of the Breast in Five Cases
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Seo KJ, An YY, Whang IY, Chang ED, Kang BJ, Kim SH, Park CS, Kim JS, Hong H
- KMID: 2160767
- Korean J Radiol.
- 2015 Oct;16(5):1006-1011.
- doi: 10.3348/kjr.2015.16.5.1006
OBJECTIVE: To evaluate the sonographic features of invasive apocrine carcinoma (IAC) of the breast. MATERIALS AND METHODS: This study included five pathologically proven cases of IAC, and their sonographic features were... -
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- Mechanisms of Apoptosis on Human Lens Epithelium after Ultraviolet Light Exposure
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Kim ST, Koh JW
- KMID: 1010028
- Korean J Ophthalmol.
- 2011 Jun;25(3):196-201.
- doi: 10.3341/kjo.2011.25.3.196
PURPOSE: The purpose of this study is to understand the mechanism of apoptosis occurring on a cultured human lens epithelial cell line after exposure to ultraviolet (UV) light. We intended... -
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- Anthocyanin Induces Apoptosis of DU-145 Cells In Vitro and Inhibits Xenograft Growth of Prostate Cancer
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Ha US, Bae WJ, Kim SJ, Yoon BI, Hong SH, Lee JY, Hwang TK, Hwang SY, Wang Z, Kim SW
- KMID: 2352784
- Yonsei Med J.
- 2015 Jan;56(1):16-23.
- doi: 10.3349/ymj.2015.56.1.16
PURPOSE: To investigate the effects of anthocyanins extracted from black soybean, which have antioxidant activity, on apoptosis in vitro (in hormone refractory prostate cancer cells) and on tumor growth in... -
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- The Bacterial Protein Azurin Enhances Sensitivity of Oral Squamous Carcinoma Cells to Anticancer Drugs
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Choi JH, Lee MH, Cho YJ, Park BS, Kim S, Kim GC
- KMID: 1108070
- Yonsei Med J.
- 2011 Sep;52(5):773-778.
- doi: 10.3349/ymj.2011.52.5.773
PURPOSE: Surgical therapy is the primary treatment for oral cancer, but it can cause facial distortion. Therefore, if anticancer drugs are effective against oral cancer, they may be used preferentially.... -
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- Carcinoma ex Pleomorphic Adenoma of the Salivary Glands: Distinct Clinicopathologic Features and Immunoprofiles Between Subgroups According to Cellular Differentiation
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Kim JW, Kwon GY, Roh JL, Choi SH, Nam SY, Kim SY, Cho KJ
- KMID: 1785983
- J Korean Med Sci.
- 2011 Oct;26(10):1277-1285.
- doi: 10.3346/jkms.2011.26.10.1277
In carcinoma ex pleomorphic adenoma (CXPA), pleomorphic adenoma (PA) and diverse carcinoma components showing luminal (ductal) or non-luminal (myoepithelial) differentiation coexist. To elucidate the clinicopathological implications of cellular differentiation in... -
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- A Case of Metachronous Development of Esophageal Squamous Cell Carcinoma in the Patient with Esophageal Carcinosarcoma
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Cha RR, Jung WT, Oh HW, Kim HJ, Ha CY, Kim HJ, Kim TH, Ko GH
- KMID: 2160669
- Korean J Gastroenterol.
- 2014 Dec;64(6):364-369.
- doi: 10.4166/kjg.2014.64.6.364
Esophageal carcinosarcoma is a rare malignant esophageal neoplasm consisting of both carcinomatous and sarcomatous elements, with an incidence of 0.5%. There have been only a few case reports of carcinosarcoma... -
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- Effects of Chromosomal Polyploidy on Survival of Colon Cancer Cells
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Park SU, Choi ES, Jang YS, Hong SH, Kim IH, Chang DK
- KMID: 1128353
- Korean J Gastroenterol.
- 2011 Mar;57(3):150-157.
- doi: 10.4166/kjg.2011.57.3.150
BACKGROUND/AIMS: Tetraploid cells are frequently observed in the inflamed mucosal epithelial cells of the patients with Barrett's esophagus or chronic ulcerative colitis. Polyploidy often occurs during cell fusion, abortive cell... -
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- Collision of Three Histologically Distinct Endometrial Cancers of the Uterus
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Jang KS, Lee WM, Kim YJ, Cho SH
- KMID: 1792985
- J Korean Med Sci.
- 2012 Jan;27(1):89-92.
- doi: 10.3346/jkms.2012.27.1.89
A collision tumor is defined by the presence of two separate masses in one organ, which are pathologically distinct. We described a 70-yr-old patient who complained of abnormal vaginal bleeding... -
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- Pseudomonas aeruginosa Exotoxin A Reduces Chemoresistance of Oral Squamous Carcinoma Cell via Inhibition of Heat Shock Proteins 70 (HSP70)
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Park SR, Lee KD, Kim UK, Gil YG, Oh KS, Park BS, Kim GC
- KMID: 1071422
- Yonsei Med J.
- 2010 Sep;51(5):708-716.
- doi: 10.3349/ymj.2010.51.5.708
PURPOSE: Oral squamous carcinoma (OSCC) cells exhibit resistance to chemotherapeutic agent-mediated apoptosis in the late stage of malignancy. Increased levels of heat shock proteins 70 (HSP70) in cancer cells are... -
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- Factors Influencing the Response to High Dose Methotrexate-based Vincristine and Procarbazine Combination Chemotherapy for Primary Central Nervous System Lymphoma
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Sung KH, Lee EH, Kim YZ
- KMID: 1777887
- J Korean Med Sci.
- 2011 Apr;26(4):551-560.
- doi: 10.3346/jkms.2011.26.4.551
The authors investigated objective response rate to high dose methotrexate (HDMTX)-based combination chemotherapy in primary central nervous system lymphoma (PCNSL), and sought to identify factors that influence response to HDMTX-based... -
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