- The production and distribution of IL-6 and TNF-alpha in subcutaneous adipose tissue and their correlation with serum concentrations in Welsh ponies with equine metabolic syndrome
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Basinska K, Marycz K, Smieszek A, Nicpon J
- KMID: 2160828
- J Vet Sci.
- 2015 Mar;16(1):113-120.
- doi: 10.4142/jvs.2015.16.1.113
A main symptom of equine metabolic syndrome (EMS) in ponies is pathological obesity characterized by abnormal accumulation of fat deposits and inflammation. In this study, we analyzed the expression of... -
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- Apoptosis of T Lymphocytes Isolated from Peripheral Blood of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
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Lim SC, Ju JY, Chi SY, Ban HJ, Kwon YS, Oh IJ, Kim KS, Kim YI, Kim YC
- KMID: 1727989
- Yonsei Med J.
- 2011 Jul;52(4):581-587.
- doi: 10.3349/ymj.2011.52.4.581
PURPOSE: Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation of the airways and progressive destruction of lung parenchyma. Apoptosis is critical for the maintenance of normal tissue homeostasis... -
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- The Anti-Inflammatory Effects of Ulinastatin in Trauma Patients with Hemorrhagic Shock
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Park KH, Lee KH, Kim H, Hwang SO
- KMID: 1713843
- J Korean Med Sci.
- 2010 Jan;25(1):128-134.
- doi: 10.3346/jkms.2010.25.1.128
We investigated the use of ulinastatin in association with the suppression of polymorphonuclear leukocyte elastase (PMNE), tumor necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6), and its effects on the... -
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- Usefulness of Serum Leucine-Rich Alpha-2 Glycoprotein as a Disease Activity Biomarker in Patients with Rheumatoid Arthritis
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Ha YJ, Kang EJ, Lee SW, Lee SK, Park YB, Song JS, Choi ST
- KMID: 1794596
- J Korean Med Sci.
- 2014 Sep;29(9):1199-1204.
- doi: 10.3346/jkms.2014.29.9.1199
Our study aimed to investigate whether serum leucine-rich alpha-2-glycoprotein (LRG) levels are elevated in patients with rheumatoid arthritis (RA). In addition, we assessed their correlation with disease activity parameters and... -
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- Interleukin-10 and Tumor Necrosis Factor-alpha Polymorphisms in Vascular Access Failure in Patients on Hemodialysis: Preliminary Data in Korea
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Sung SA, Ko GJ, Jo SK, Cho WY, Kim HK, Lee SY
- KMID: 1786851
- J Korean Med Sci.
- 2008 Feb;23(1):89-93.
- doi: 10.3346/jkms.2008.23.1.89
Neointimal hyperplasia causes vascular stenosis and subsequent thrombosis, which result in vascular access failure in patients undergoing hemodialysis. Interleukin-10 (IL-10) and tumour necrosis factor-alpha (TNF-alpha) are involved in this inflammatory... -
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- Serum Pro-hepcidin Could Reflect Disease Activity in Patients with Rheumatoid Arthritis
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Kim HR, Kim KW, Yoon SY, Kim SH, Lee SH
- KMID: 1778027
- J Korean Med Sci.
- 2010 Mar;25(3):348-352.
- doi: 10.3346/jkms.2010.25.3.348
The aim of this study was to analyze the relationship between serum pro-hepcidin concentration and the anemia profiles of rheumatoid arthritis (RA) and to estimate the pro-hepcidin could reflect the... -
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- Application of the Multiplex Cytokine Analysis to Monitor Xenogeneic Immune Responses to the Porcine Islet Graft in Non-Human Primate
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Kim YH, Kim JS, Yoon IH, Shin JS, Kim JM, Kim SJ, Park CG
- KMID: 1779412
- J Korean Med Sci.
- 2013 Dec;28(12):1729-1733.
- doi: 10.3346/jkms.2013.28.12.1729
Non-human primate studies must be conducted prior to the clinical trial of xenotransplantation. In order to develop clinically applicable immune-modulatory regimen through non-human primate studies, close monitoring of xenogeneic immune... -
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- The Association of the Activation-Inducible Tumor Necrosis Factor Receptor and Ligand with Lumbar Disc Herniation
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Park MS, Lee HM, Hahn SB, Moon SH, Kim YT, Lee CS, Jung HW, Kwon BS, Riew KD
- KMID: 1122623
- Yonsei Med J.
- 2007 Oct;48(5):839-846.
- doi: 10.3349/ymj.2007.48.5.839
PURPOSE: Herniated nucleus pulposus fragments are recognized by the immune system as a foreign-body, which results in an autoimmune reaction. Human activation-inducible tumor necrosis factor receptor (AITR) and its... -
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- GSTM1 and GSTP1 Polymorphisms as Potential Factors for Modifying the Effect of Smoking on Inflammatory Response
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Kim JH, Park SG, Lee KH, Choi JH, Ha EH, Myung SK, Hong YC
- KMID: 1713112
- J Korean Med Sci.
- 2006 Dec;21(6):1021-1027.
- doi: 10.3346/jkms.2006.21.6.1021
Inflammation has been known to be an important underlying condition for development of various diseases including cancer. The aims of this study were to investigate whether tobacco smoke exposure increases... -
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- Comparison of the Child-Turcotte-Pugh Classification and the Model for End-stage Liver Disease Score as Predictors of the Severity of the Systemic Inflammatory Response in Patients Undergoing Living-donor Liver Transplantation
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Hong SH, Kim JE, Cho ML, Heo YJ, Choi JH, Choi JH, Lee J
- KMID: 1785992
- J Korean Med Sci.
- 2011 Oct;26(10):1333-1338.
- doi: 10.3346/jkms.2011.26.10.1333
The aim of this study was to evaluate and compare the Child-Turcotte-Pugh (CTP) classification system and the model for end-stage liver disease (MELD) score in predicting the severity of the... -
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- The stress of weaning influences serum levels of acute-phase proteins, iron-binding proteins, inflammatory cytokines, cortisol, and leukocyte subsets in Holstein calves
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Kim MH, Yang JY, Upadhaya S, Lee HJ, Yun CH, Ha JK
- KMID: 1106557
- J Vet Sci.
- 2011 Jun;12(2):151-157.
- doi: 10.4142/jvs.2011.12.2.151
The purpose of our study was to investigate changes in immunological parameters induced by weaning stress (including milk restriction) in calves. Fifteen Holstein calves were subjected to weaning at 6... -
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- Measurement of antioxidant capacity using the biological antioxidant potential test and its role as a predictive marker of metabolic syndrome
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Kim JH, Baik HW, Yoon YS, Joung HJ, Park JS, Park SJ, Jang EJ, Park SW, Kim SJ, Kim MJ, Jeon DO, Cho HJ, Lee SJ, Im SG, Jang SK
- KMID: 1792010
- Korean J Intern Med.
- 2014 Jan;29(1):31-39.
- doi: 10.3904/kjim.2014.29.1.31
BACKGROUND/AIMS: Oxidative stress increases the risk of cardiovascular complications of metabolic syndrome (MetS). This study was conducted to examine the difference in antioxidant capacity according to the presence of MetS,... -
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- Ethanol extract of Angelica gigas inhibits croton oil-induced inflammation by suppressing the cyclooxygenase - prostaglandin pathway
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Shin S, Joo SS, Park D, Jeon JH, Kim TK, Kim JS, Park SK, Hwang BY, Kim YB
- KMID: 1106156
- J Vet Sci.
- 2010 Mar;11(1):43-50.
- doi: 10.4142/jvs.2010.11.1.43
The anti-inflammatory effects of an ethanol extract of Angelica gigas (EAG) were investigated in vitro and in vivo using croton oil-induced inflammation models. Croton oil (20 microgram/mL) up-regulated mRNA expression... -
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- Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model
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Choi Y, Park SK, Kim HM, Kang JS, Yoon YD, Han SB, Han JW, Yang JS, Han G
- KMID: 1104812
- Exp Mol Med.
- 2008 Oct;40(5):574-581.
- doi: 10.3858/emm.2008.40.5.574
In light of the anti-inflammatory properties of histone deacetylase (HDAC) inhibitors, such as suberoylanilide hydroxamic acid (SAHA) and trichostatin A (TSA), we examined a new HDAC inhibitor KBH-A42 for its... -
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- Changes of Body Weight and Inflammatory Markers after 12-Week Intervention Trial: Results of a Double-Blind, Placebo-Control Pilot Study
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Joo NS, Kim SM, Kim KM, Kim CW, Kim BT, Lee DJ
- KMID: 1779658
- Yonsei Med J.
- 2011 Mar;52(2):242-248.
- doi: 10.3349/ymj.2011.52.2.242
PURPOSE: Low grade inflammation is a well-known characteristic in obese subjects. We investigated body weight changes and inflammatory markers after 12-week intervention trial. MATERIALS AND METHODS: Twenty-six obese subjects were enrolled... -
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- Obesity aggravates the joint inflammation in a collagen-induced arthritis model through deviation to Th17 differentiation
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Jhun JY, Yoon BY, Park MK, Oh HJ, Byun JK, Lee SY, Min JK, Park SH, Kim HY, Cho ML
- KMID: 1397446
- Exp Mol Med.
- 2012 Jul;44(7):424-431.
White fat cells secrete adipokines that induce inflammation and obesity has been reported to be characterized by high serum levels of inflammatory cytokines such as IL-6 and TNF-alpha. Rheumatoid arthritis... -
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- Chronic ethanol feeding impairs AMPK and MEF2 expression and is associated with GLUT4 decrease in rat myocardium
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Chen L, Wang F, Sun X, Zhou J, Gao L, Jiao Y, Hou X, Qin C, Zhao J
- KMID: 946653
- Exp Mol Med.
- 2010 Mar;42(3):205-215.
- doi: 10.3858/emm.2010.42.3.021
Chronic and heavy alcohol consumption is one of the causes of heart diseases. However, the effects of ethanol on insulin sensitivity in myocardium has been unclear. To investigate the effects... -
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