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Effect of glucose on the expression of c-myc gene in cultured RINm5F cell

Kim SW, Yang IM, Kim JW, Kim YS, Kim KW, Choi YK, Suh KS

The study was designed to examine the effect of glucose on the expression of c-myc gene in cultured RINm5F cells. After monolayer culture was established in RPMI 1640 media supplemented...
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Dose-dependent effect of resveratrol on proliferation and apoptosis in endothelial and tumor cell cultures

Szende B, Tyihak E, Kiraly-Veghely Z

  • KMID: 1109308
  • Exp Mol Med.
  • 2000 Jun;32(2):88-92.
Experimental data suggest that Resveratrol, a compound found in grapes and other fruits may influence cell proliferation and apoptosis. The aim of our experiments was to study the effect of...
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Effect of cytokines on the expression of cell adhesion molecule and on the adhesion of melanoma cells to endothelial cells

Kim SJ, Kim NS, Lee JL

We examined the role of cell adhesion molecules (CAM) by which tumor cells bind to the endothelial cells using human umbilical vein endothelial cells (HUVEC) and cultured melanoma cells. Endothelial...
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Partial purification and characterization of a novel murine factor that augments the expression of class I MHC antigens on tumor cells

Puri N, Saxena RK

  • KMID: 754994
  • Exp Mol Med.
  • 1998 Jun;30(2):93-99.
A soluble factor which augments the expression of major histocompatibility complex class I (MHC I) antigens on a number of murine tumor cell lines, has been isolated from the culture supernatants of...
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The Effects of Ginsenoside Rb1 on the Apoptosis and the Production of Nitric Oxide in Rat C6 Glioma Cells

Park JH, Lee YH, Kang KS, Lee SK, Kim SZ, Park JY, Kwak EK, Sohn YK

  • KMID: 2275519
  • Korean J Pathol.
  • 2004 Feb;38(1):1-7.
BACKGROUND: Ginsenosides, the extract of Panax ginseng, exert various pharmacological effects such as anticancer activity by the mechanism that is not yet defined. In this study, we proposed that the...
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Apoptosis

Kim IK

No abstract available.
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Application of Cell Culture with Immunocytochemistry and Electron Microscopy to the Diagnosis of Central Neurocytoma

Kim IY, Kim JH, Lee MC, Kim TS, Kim SH, Lee JH, Kang SS

  • KMID: 2188134
  • J Korean Neurosurg Soc.
  • 1997 Nov;26(11):1483-1492.
The purpose of this study was to determine the value of primary cell culture in combination with histololgical techniques as a method for the diagnosis of central neurocytoma ;...
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Visualization of Tumor Angiogenesis Using MR Imaging Contrast Agent Gd-DTPA-anti-VEGF Receptor 2 Antibody Conjugate in a Mouse Tumor Model

Jun HY, Yin HH, Kim SH, Park SH, Kim HS, Yoon KH

OBJECTIVE: To visualize tumor angiogenesis using the MRI contrast agent, Gd-DTPA-anti-VEGF receptor 2 antibody conjugate, with a 4.7-Tesla MRI instrument in a mouse model. MATERIALS AND METHODS: We designed a...
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The mechanism of antiproliferative effect of desferrioxamine on human hepatoma cell lines

Kim DY, Kim WH, Kang JK, Park IS, Kwon OH

We investigated the effect of desferrioxamine (DFO), an iron chelator, on the DNA synthesis and the cell cycle of cultured hepatoma cells. Using Hep 3B cells as the hepatoma cell...
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Culture Characteristics of Oligodendroglioma and Central Neurocytoma

Kang MG, Lee MC, Jung S, Kim JH, Kang SS, Oh MS

  • KMID: 1956072
  • J Korean Neurosurg Soc.
  • 1999 Sep;28(9):1257-1263.
OBJECTIVE: Intra or periventricular tumors of the central nervous system such as oligodendroglioma and central neurocytoma, are frequently associated with hydrocephalus and histologically share the presence of relatively uniform, small...
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The effect of cyclophosphamide on Fas-mediated apoptosis

Lee JH, Park JH, Yang MH

Fas is a cell surface protein that can mediate apoptosis and belongs to the tumor necrosis factor (TNF) receptor family. Anti-Fas antibody induces apoptotic cell death in...
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Retroviral-mediated IL-2 gene transfer into murine neuroblastoma

Cho HS, Song JY, Park CY, Lyu CJ, Kim BS, Kim KY

We used retroviral-mediated gene transfer of the human interleukin (IL)-2 gene into murine neuroblastoma cells to investigate whether locally-secreted IL-2 is able to influence the generation of anti-tumor immune responses....
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In vitro infection of Cryptosporidium parvum to four different cell lines

Yu JR, Choi SD, Kim YW

To determine a suitable condition for in vitro infection model of Cryptosporidium parvum, four different cell lines, AGS, MDCK, HCT-8 and Caco-2, were used as host cell lines which were...
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Relationship between Melanogenicity and Malignancy in Malignant Melanoma Cells

Kim HI, Youn JK, Park YK

Though the malignancy of a tumor is generally postulated to be affected by the degree of differentiation of tumor cells, the relationship between differentiation and malignancy of tumors has...
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Inhibition of HBV replication by antisense oligodeoxyribonucleotides in HepG2 cells transfected with a cloned HBV DNA

Oh SH, Yeh BI, Kim SH

The effect of antisense oligodeoxyribonucleotides(oligo[dN]s) on hepatitis B virus(HBV) replication in HepG2 cells harboring a cloned HBV genome was examined. Antisense oligo(dN)s directed at translational initiation sites of S, pre...
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Combination treatment for osteosarcoma with baculoviral vector mediated gene therapy (p53) and chemotherapy (adriamycin)

Song SU, Boyce FM

  • KMID: 755117
  • Exp Mol Med.
  • 2001 Mar;33(1):46-53.
The insect baculovirus Autographa californica multiple nuclear polyhedrosis virus (AcMNPV) has been evaluated as a vector for gene delivery to human tumor cells. A human osteogenic sarcoma cell line, Saos-2,...
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Anti-retroviral effect of chlorophyll derivatives (CpD-D) by photosensitization

Lee M, Lee Y

A new photosensitizer, CpD(chlorophyll derivatives), previously reported as a promising agent for tumor therapy, was studied to determine its inhibitory effects on Gross leukemia virus(GLV), a mouse retrovirus isolated from...
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Effects of New Nultidrug - Resistance Reversing Agent, KR-30035, on Tumoral Uptake of Tc-99m MIBI In-vitro and In-vivo

Cho IH, Lee J, Suh JS, Lee BH, Choi SW, Sohn SK, Lee CO, Yoo SE, Chung JK, Lee KB

  • KMID: 2329172
  • J Korean Cancer Assoc.
  • 1999 Aug;31(4):773-783.
PURPOSE: Verapamil is one of the most extensively characterized modulators of P-glyco- protein (P-gp) mediated multi-drug resistance (MDR), but its plasma concentration required to reverse MDR can cause cardiovascular toxicity....
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Effects of iodinated fatty acid ester on human hepatocellular carcinoma cells

Kim H, Park C, Lee YB, Yoo HS, Park JH, Lee WY

The interaction between Lipiodol and cells was studied by treating Lipiodol in a human hepatocellular carcinoma cell line(Hep) and mouse fibroblast cell line (L929). Irregular, sustained radioactivity was released from...
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Cloning of BNIP3h, a member of proapoptotic BNIP3 family genes

Farooq M, Kim YH, Im SU, Chung EJ, Hwang SY, Sohn MY, Kim MK, Kim JC

  • KMID: 938882
  • Exp Mol Med.
  • 2001 Sep;33(3):169-173.
Apoptosis is regulated by interaction of antiapoptotic Bcl-2 family proteins with various proapoptotic proteins, several of which are also members of the Bcl-2 family. BNIP3 (formerly NIP3) is a proapoptotic...
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