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Effects of Oncostatin M on Invasion of Primary Trophoblasts under Normoxia and Hypoxia Conditions

Wie JH, Ko HS, Choi SK, Park IY, Kim A, Kim HS, Shin JC

PURPOSE: To investigate the effect of oncostatin M (OSM) on protein expression levels and enzymatic activities of matrix metalloprotainase (MMP)-2 and MMP-9 in primary trophoblasts and the invasiveness thereof under...
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Effects of hypoxia inducible factors-1alpha on autophagy and invasion of trophoblasts

Choi JH, Lee HJ, Yang TH, Kim GJ

OBJECTIVE: This study was undertaken to determine the effect of hypoxia inducible factor (HIF)-1alpha on the cell death, autophagy, and invasion of trophoblasts. METHODS: To understand the effect of HIF-1alpha, we...
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Histological and Immunohistochemical Findings of the Intermediate Trophoblasts in Normal Full Term and Pre-eclamptic Placentas

Han SH, Kim KR, Lee Y, Ro JY

  • KMID: 2277625
  • Korean J Pathol.
  • 2010 Feb;44(1):63-69.
BACKGROUND: Recent studies have suggested that implantation site intermediate trophoblasts (ISITs) and chorionic type intermediate trophoblasts (CTITs) show different immunohistochemical findings, and that each type has specific location in placentas....
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The Influence of Human Chorionic Gonadotropin and Human Placental Lactogen on Growth and Differentiation of Placental Trophoblast

Kim DJ, Ahn HY, Roh SR, Kang MJ, Baik EJ, Shin JC, Namkoong S, Bae SN

  • KMID: 1887693
  • Korean J Obstet Gynecol.
  • 2001 Jul;44(7):1262-1268.
BACKGROUND: There are many factors that influence the differentiation and growth of trophoblasts. During differentiation of trophoblasts, two major hormones are secreted ; human chorionic gonadotropin (hCG) and human placental...
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Influence of Hypoxic Condition on Invasion of Cultured Trophoblast

Baik EJ, Shin JC, Jung DY, Yang DE, Kim JD, Rho SH, Lee JS, Kim SJ, Kim CI, Kim SP

  • KMID: 2072005
  • Korean J Perinatol.
  • 1999 Dec;10(4):498-507.
OBJECTIVE: To investigated whether lowering oxygen tension affects invasion of cultured trophoblast. METHODS: Trophoblasts were isolated from the normal placenta in early pregnancy(6-10 weeks in gestation). Isolated trophoblasts were cultured...
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Effects of selenium on the survival and invasion of trophoblasts

Na JY, Seok J, Park S, Kim JS, Kim GJ

OBJECTIVE: Placental oxidative stress is known to be a factor that contributes to pregnancy failure. The aim of this study was to determine whether selenium could induce antioxidant gene expression...
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Epithelioid Trophoblastic Tumor in a Postmenopausal Woman: A Case Report

Park JW, Bae JW

Epithelioid trophoblastic tumor (ETT) is a rare gestational trophoblastic neoplasm composed of intermediate trophoblasts. Most cases of ETT are reported in women of reproductive age following a prior gestation within...
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Differential Expressions of Fas and Fas Ligand in Human Placenta

Roh CR, Lee JW, Kang BH, Yang SH, Kim BG, Bae DS, Kim JH, Lee JH

To investigate the expressions of Fas and Fas ligand (FasL) in human placenta, we studied the expressions of Fas and FasL in placenta with RT-PCR, immunoblotting and immunostaining. We observed...
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Co-localization and interaction of human organic anion transporter 4 with caveolin-1 in primary cultured human placental trophoblasts

Lee WK, Choi JK, Cha SH

The human organic anion transporter 4 (hOAT4) has been identified as the fourth isoform of OAT family. hOAT4 contributes to move several negatively charged organic compounds between cells and their...
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Changes in urinary pseudouridine excretion by patients with trophoblastic diseases during anticancer chemotherapy

Oh ST

  • KMID: 1696496
  • Korean J Obstet Gynecol.
  • 1991 Jan;34(1):101-115.
No abstract available.
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Cytolgic features of placental site trophoblastic tumor-a case report of cervico-vaginal smear-

Park HR, Lee YW, Park YE

  • KMID: 1684824
  • Korean J Cytopathol.
  • 1993 Dec;4(2):150-155.
No abstract available.
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Effects of estradiol on HIF-1α expression and trophoblast differentiation in first trimester villous explant cultures

Cho GJ, Lee LH, Lee B, Lee J, Ahn KH, Hong SC, Kim HJ, Oh MJ

OBJECTIVE: The purpose of this study was to investigate the effects of estradiol on the expression of hypoxia-inducible factor (HIF)-1α and the differentiation of trophoblasts in human first trimester villous...
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A case of placenta site trophoblastic tumor(PSTT)

Shin HT, Lee SK, Hum CY, Kim SB

  • KMID: 1697905
  • Korean J Obstet Gynecol.
  • 1993 Dec;36(12):3976-3982.
No abstract available.
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Autophagy in the placenta

Oh SY, Roh CR

Autophagy is an evolutionarily conserved catalytic process by which cytoplasmic components including damaged macromolecules and organelles are degraded. The role of autophagy includes adaptive responses to nutrition deprivation or intracellular...
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Plasmin System in Placenta from Women with Normal and Preeclamptic Pregnancy

Roh CR, Lee JH, Yoon BK

  • KMID: 2261361
  • Korean J Obstet Gynecol.
  • 1999 Mar;42(3):539-543.
OBJECTIVES: the aim of this study was to evaluate plasmin system in placenta fiom women with normal and preeclamptic pregnancy. METHODS: The levels of urokinase-type plasminogen activator(uPA), tissue-type plasrninogen activator(tPA),...
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Primary Choriocarcinoma of the Stomach: A Case Report

Seo EJ, Kwon HJ, Min KO, Lim KW, Lee S, Kim BK

  • KMID: 2275581
  • Korean J Pathol.
  • 2002 Feb;36(1):55-58.
A case of primary gastric choriocarcinoma with multiple liver metastases is described. A 54-year-old man underwent gastrectomy for an advanced cancer. An ulcerofungating tumor with extensive hemorrhagic necrosis was found...
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Telomerase and Apoptosis in the Placental Trophoblasts of Growth Discordant Twins

Kim SY, Lee SP, Lee JS, Yoon SJ, Jun G, Hwang YJ

In an effort to investigate the molecular basis of growth discordance in embryos that experience the same uterine environment, we compared telomerase activity and apoptosis in placental trophoblasts obtained from...
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TonEBP and SMIT expression in human placenta

Shin JA, Kwon HM, Han KH, Lee HY

Tonicity-responsive enhancer binding protein (TonEBP) is a signal transcription factor of transporters such as sodium-myo-inositol cotransporter (SMIT), aldose reductase. TonEBP has a variety of functions such as control of intracellular...
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Influence of Hypoxia on Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor in Cultured Human Trophoblast

Lee Y, Shin JC, Yang DE, Moon HB, Lee GS, Kim SJ, Lee JS, Kim CE, Kim SP

  • KMID: 2076851
  • Korean J Obstet Gynecol.
  • 2003 Mar;46(3):617-623.
OBJECTIVE: To investigate whether the hypoxic condition influences on the expression of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) mRNA in the cultured human trophoblast. METHODS: Trophoblasts...
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Clinical study on trophoblastic disease

Kim SW, Chun HS, Kim HS, Kim YL, Park SK

  • KMID: 2259476
  • Korean J Obstet Gynecol.
  • 1993 Jul;36(7):1058-1067.
No abstract available.
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