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A Study on the Effect of Various Dosage of Khellin on Epidermal Melanocytes and a Comparison with Trimethylpsoralen in Systemic Photochemotherapy

Yoon MS, Hong KT, Park YK

  • KMID: 1891652
  • Korean J Dermatol.
  • 1988 Dec;26(6):828-838.
Ninety black C 57 BL mice were divided into control and photochemotherapy groups. Control group was subdivided into a UVA 1rradiation only subgroup and a khellin only administration subgroup, while...
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Study on the Pigment Producing Effect of Various Concentrations of Trimethylpsoralen in Topical Photochemotherapy

Park YK, Whang KC

  • KMID: 1679755
  • Korean J Dermatol.
  • 1987 Apr;25(2):234-239.
Topical photochemotherapy is effective for the treatment of vitiligo, However the effectiveness of photosensitizer, 4,5', 8-trimethyl-psoralen is not well known. For thesie reasons, we evaluated the pigment producing effect of...
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Study of the skin concentrations after administration of the various phototoxic drugs

Park YK, Hann SK, Cho MY, Kim HJ, Shim SC, Choi SJ, Yun MH

The skin concentrations of 8-methoxypsoralen (8-MOP), 5-methoxypsoralen (5-MOP), and 4, 5', 8-trimethylpsoralen (TMP) were studied in the guinea pig following oral administration and bathing. The skin concentration of phototoxic drugs...
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Quantitative and Morphologic Changes of Epidermal Langerhans Cell after Photochemotherapy in Guinea Pigs

Kim SC, Park YK

We studied the number and morphologic alterations of ATPase-positive Langerhans cells (LCs) in guinea pig epidermal sheets and also performed electron microscopic observations on them following long-term systemic psoralen photochemotherapy...
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