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The DPE, a core promoter element for transcription by RNA polymerase II

Kadonaga J

  • KMID: 931875
  • Exp Mol Med.
  • 2002 Sep;34(4):259-264.
The core promoter is an important yet often overlooked component in the regulation of transcription by RNA polymerase II. In fact, the core promoter is the ultimate target of...
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Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions

Lee JW, Bae SH, Jeong JW, Kim SH, Kim KW

  • KMID: 755659
  • Exp Mol Med.
  • 2004 Feb;36(1):1-12.
Hypoxia-inducible factor (HIF-1) is an oxygen-dependent transcriptional activator, which plays crucial roles in the angiogenesis of tumors and mammalian development. HIF-1 consists of a constitutively expressed HIF-1beta subunit and one...
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Oxygen-Dependent and -Independent Regulation of HIF-1alpha

Chun YS, Kim MS, Park JW

Hypoxia-inducible factor-1 (HIF-1) is composed of HIF-1alpha and HIF-1beta, and is a master regulator of oxygen homeostasis, playing critical roles in physiological and pathological processes. Normally, the formation and...
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