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Dissecting the molecular mechanism of nuclear receptor action: transcription coactivators and corepressors

Lee JW, Cheong JH, Lee YC, Na SY, lee SK

  • KMID: 1109302
  • Exp Mol Med.
  • 2000 Jun;32(2):53-60.
No abstract available.
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Expression of beta-catenin in Hepatocellular Carcinoma in Relation to Tumor Cell Proliferation and Cyclin D1 Expression

Joo M, Lee HK, Kang YK

Alteration of beta-catenin expression has been implicated in the development of hepatocellular carcinoma (HCC). It has been also reported that beta-catenin can influence the tumor cell proliferation or cyclin D1...
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B6C3F1 mice exposed to ozone with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate showed toxicities through alterations of NF-kappaB, AP-1, Nrf2, and osteopontin

Kim MY, Song KS, Park GH, Chang SH, Kim HW, Park JH, Jin H, Eu KJ, Cho HS, Kang G, Kim YC, Cho MH

  • KMID: 1120069
  • J Vet Sci.
  • 2004 Jun;5(2):131-137.
Toxic effects of ozone, 4-(N-methyl-N-nitrosamino)-1-(3- pyridyl)-1-butanone (NNK), and/or dibutyl phthalate (DBP) were examined through NF-kappaB, AP-1, Nrf2, and osteopontin (OPN) in lungs and livers of B6C3F1 mice. Electrophoretic mobility shift...
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Activation of PPARgamma induces profound multilocularization of adipocytes in adult mouse white adipose tissues

Koh YJ, Park BH, Park JH, Han J, Lee IK, Park JW, Koh GY

We sought to determine the effects of activation of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) on multilocularization of adipocytes in adult white adipose tissue (WAT). Male C57BL/6 normal, db/db, and ob/ob mice...
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Efficient Cultivation Conditions for Human Limbal Epithelial Cells

Kim MK, Lee JL, Oh JY, Shin MS, Shin KS, Wee WR, Lee JH, Park KS, Son YS

To compare the stem niche in different culture conditions of limbal epithelial cells, the suspended human limbal epithelial cells (HLECs) were seeded on the 3T3-pretreated plates and the other suspended...
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Transforming variant of Met receptor confers serum independence and anti-apoptotic property and could be involved in the mouse thymic lymphomagenesis

Baek CM, Jeon SH, Jang JJ, Lee BS, Lee JH

  • KMID: 1094072
  • Exp Mol Med.
  • 2004 Aug;36(4):283-291.
Met tyrosine kinase receptor, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), is present in mouse tissues as two major isoforms differing by a 47-aminoacid segment in the juxtamembrane domain...
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Differentiation of human labia minora dermis-derived fibroblasts into insulin-producing cells

Kim B, Yoon BS, Moon JH, Kim J, Jun EK, Lee JH, Kim JS, Baik CS, Kim A, Whang KY, You S

Recent evidence has suggested that human skin fibroblasts may represent a novel source of therapeutic stem cells. In this study, we report a 3-stage method to induce the differentiation of...
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Statin inhibits interferon-gamma-induced expression of intercellular adhesion molecule-1 (ICAM-1) in vascular endothelial and smooth muscle cells

Chung HK, Lee IK, Kang HK, Suh JM, Kim H, Park KC, Kim DW, Kim YK, Ro HK, Shong MH

  • KMID: 1121099
  • Exp Mol Med.
  • 2002 Dec;34(6):451-461.
Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, known as statins, are widely used for primary and secondary prevention of coronary artery atherosclerosis. Pathogenesis of atherosclerosis is multistep processes where...
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