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Correction to: Surface Creasing-Induced Micropatterned GelMA Using Heating-Hydration Fabrication for Effective Vascularization

Kasetsirikul S, Ketpun D, Chuah YJ, Sriphutkiat Y, Wang DA, Zhou Y

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Advances in Research on Stem Cell-Based Pulp Regeneration

Lee HN, Liang C, Liao L, Tian WD

Although root canal therapy is the most common and widely used treatment at clinical presentation, there are still some postoperative complications. As cell biology and tissue engineering techniques advance rapidly,...
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Research Models of the Nanoparticle-Mediated Drug Delivery across the Blood–Brain Barrier

Li QY, Lee JH, Kim HW, Jin GZ

Brain diseases and damages come in many forms such as neurodegenerative diseases, tumors, and stroke. Millions of people currently suffer from neurological diseases worldwide. While Challenges of current diagnosis and...
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Stabilization of Lipid Lamellar Bilayer Structure of Stratum Corneum Modulated by Poly (2-methacryloyloxyethyl phosphorylcholine) in Relation to Skin Hydration and Skin Protection

Lee ARC, Moon H, Ishihara K

BACKGROUND: One crucial factor in skin tissue engineering is to understand the hydration and barrier property of skin. We investigated the skin hydration and stabilization strategy of inter-lamellar structure of...
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Comparative Evaluation of Connective Tissue Graft with Pouch/ Tunnel Technique versus Connective Tissue Graft with Coronally Advanced Tunnel Flap for the Treatment of Maxillary Recession Cases in Severe Periodontitis

Tian W, Hu F, Zhou X

BACKGROUND: The long-term stability for both the patient and periodontist remains an important priority after connective tissue graft to manage the gingival recession cases. The goal of this analysis was...
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Intra-Articular Injection of miR-29a-3p of BMSCs Promotes Cartilage Self-Repairing and Alleviates Pain in the Rat Osteoarthritis

Wang Q, Chen Y, Shen X, Chen J, Li Y

BACKGROUND: Stem cells intra-articular injection stagey indicated a potential therapeutic effect on improving the pathological progress of osteoarthritis (OA). However, the long-term effect of stem cells intra-articular injection on the...
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Effect of Human Umbilical Cord Matrix-Derived Mesenchymal Stem Cells on Bisphosphonate-Related Osteonecrosis of the Jaw

Yang G, Kim YN, Kim H, Lee BK

BACKGROUND: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe sequela caused by bisphosphonates (BPs), which are widely used to treat osteoporosis or other malignancies. However, the mechanism underlying BRONJ...
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Three-Dimensional Modeling of the Structural Microenvironment in Post-Traumatic War Wounds

Christopherson GT, Vasconcellos JFd, Dunn JC, Griffin DW, Jones PE, Nesti LJ

BACKGROUND: The development of post-traumatic heterotopic ossification (HO) is a common, undesirable sequela in patients with high-energy (war-related) extremity injuries. While inflammatory and osteoinductive signaling pathways are known to be...
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Kartogenin Promotes the BMSCs Chondrogenic Differentiation in Osteoarthritis by Down-Regulation of miR-145-5p Targeting Smad4 Pathway

Liu H, Liu P

BACKGROUND: Transplantation of mesenchymal stem cells (MSCs) is a potential therapeutic strategy for cartilage degeneration of osteoarthritis (OA). But controlling chondrogenic differentiation of the implanted MSCs in the joints remains...
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Extracorporeal Shock Wave Combined with TeriparatideLoaded Hydrogel Injection Promotes Segmental Bone Defects Healing in Osteoporosis

Chen Q, Xia C, Shi B, Chen C, Yang C, Mao G, Shi F

BACKGROUND: Osteoporosis is a systemic bone disease characterized by decreased bone density and deterioration of bone microstructure, leading to an increased probability of fragility fractures. Once segmental bone defect occurs,...
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Near-infrared Transillumination and Photodynamic Therapy Using Hypericin in Animal Laryngeal Tumors

Lee H, Kim SW, Kwon DY, Kang HW, Jung MJ, Kim JH, Ahn YC, Oak C

BACKGROUND: We aimed to validate a pilot study of photodiagnosis using near infrared (NIR) transillumination and assess the clinical efficacy of hypericin-mediated photodynamic therapy (HYP-PDT) in a rabbit laryngeal cancer...
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Polydeoxyribonucleotide and Polynucleotide Improve Tendon Healing and Decrease Fatty Degeneration in a Rat Cuff Repair Model

Hwang JT, Lee SS, Han SH, Sherchan B, Panakkal JJ

BACKGROUND: After surgical repair of chronic rotator cuff tears, healing of the repaired tendons often fails and is accompanied by high-level fatty degeneration. Our purpose was to explore the effects...
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Extracellular Vesicles from Adipose-Derived Stem Cells Promote Diabetic Wound Healing via the PI3K-AKT-mTOR-HIF-1a Signaling Pathway

Liu W, Yuan Y, Liu D

BACKGROUND: Impaired potential of hypoxia-mediated angiogenesis lead poor healing of diabetic wounds. Previous studies have shown that extracellular vesicles from adipose derived stem cells (ADSC-EVs) accelerate wound healing with unelucidated...
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