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Significance of thymidine kinase activity in the gastrointestinal cancers

Roh SK, Chung YW, Kim JH, Lee SJ, Kwun KB

  • KMID: 1742121
  • J Korean Cancer Assoc.
  • 1991 Jun;23(2):230-236.
No abstract available.
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Chemosensitivity of cancer cells to anticancer drugs using dye exclusion assay,[3H] thymidine incorporation,and clonogenic assay

Jin WJ

  • KMID: 1690353
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 1993 Apr;15(1):35-48.
No abstract available.
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Cloning and map location of thymidine kinase(TK) gene of Korean isolate bovine herpesvirus PQ strain

Kweon CH, Kee YJ, Kwon BJ, An SH

  • KMID: 1688659
  • J Korean Soc Virol.
  • 1993 Dec;23(2):165-169.
No abstract available.
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Increased Thymidine Kinase Activity and in vitro Bystander Effect by Double Transfer of HSVtk Gene into T98G Tumor Cells

Kim YG

  • KMID: 2188358
  • J Korean Neurosurg Soc.
  • 1999 Mar;28(3):293-299.
Transduction of retroviral-mediated herpes simplex virus thymidine kinase(HSVtk) gene into tumor cells and subsequent ganciclovir(GCV) treatment have been used as an experimental and clinical therapeutic strategy. Because non-transduced tumor cells...
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Autoradiographic study on the uptake of (3)H-6-thymidine by Fasciola hepatica

Kim JH

Autoradiographic study was performed in order to know the distribution of exogenous radioactive substance, (3)H-6-Thymidine, by liver fluke, Fasciola hepatica. The worms were maintained in vitro for 1 hour, at...
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Development of inhibitors of pyrimidine metabolism

Cha S

Benzylacyclouridines were developed as specific and potent competitive inhibitors of uridine phosphorylase with Ki values in the nanomolar range. These compounds have no activity against thymidine phosphorylase, uridine kinase,...
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Immunohistochemical Study on the Expression of Thymidine Phosphorylase and Ki-67 in the Uterine Cervical Neoplasia

Jun S, Han HS, Kim CJ, Bae DH, Kim MK

  • KMID: 2270300
  • Korean J Obstet Gynecol.
  • 2002 Jun;45(6):1033-1039.
OBJECTIVE: We evaluated the relationship between the expression of Ki-67 and thymidine-phosphorylase (TP) according to the cancerous progression of uterine cervical cancer with immunohistochemical method. METHODS: The material was obtained...
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The Effect of Calcitonin Gene-Related Peptide on Hair Growth in Vitro

Suh DH, Eun HC

BACKGROUND: Calcitonin gene-related peptide(CGRP)-containing nerve fibers are widely distributed in the skin including the area around hair follicles. OBJECTIVE: This study was undertaken to investigate the effect of CGRP on normal...
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Nuclear Imaging of Cellular Proliferation

Yeo JS

  • KMID: 2078813
  • Korean J Nucl Med.
  • 2004 Apr;38(2):198-204.
Tumor cell proliferation is considered to be a useful prognostic indicator of tumor aggressiveness and tumor response to therapy, but in vitro measurement of individual proliferation is complex and tedious...
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In Vitro Effect of Cyclosporin A on Corneal Endothelial Cells

Tchah H

  • KMID: 2124701
  • J Korean Ophthalmol Soc.
  • 2000 Jun;41(6):1297-1303.
Cyclosporin (CsA)is a potent immunosuppressive agent and is used for prevention of corneal graft rejection.In vitro effects of CsA on the cultured rabbit corneal endothelial cells and the rat corneal...
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The effects of mechanical force on cultured periodontal ligament cells in vitro

Kim HY, Cha KS

  • KMID: 2271383
  • Korean J Orthod.
  • 1994 Jun;24(2):295-301.
The movement of teeth during orthodontic treatment requires bone remodeling process in periodontal tissue. To find out the changes occuring in the cell itself, mechanical force was applied to the...
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The Effects of Hydrogen Peroxide on the Migration and Proliferation of the Human Keratinocytes during Wound Healing

Park HJ, Lee JH

  • KMID: 1548109
  • Korean J Dermatol.
  • 1999 Mar;37(3):352-357.
BACKGROUND: Various topical antisepties are often used for postoperative care of surgical wounds. But the effect of these agent on wound healing remains an area of debate. OBJECTIVE: The purpose...
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The effects of insulin-like growth factors on the proliferation of endometrial stromal cells from patients with and without endometriosis

Kim MH, Lee GW, Lee YH, Kim JG

  • KMID: 2261844
  • Korean J Obstet Gynecol.
  • 2000 Feb;43(2):286-294.
OBJECTIVES: To test the hypothesis that the endometrial stromal cells from patients with endometriosis responds differently to the insulin-like growth factor (IGF) compared with those from patients without endometriosis. METHODS:...
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Cloning, Sequencing and Expression in Escherichia coli of Herpes simple virus Type-1 Thymidine Kinase Gene

Lee HB, Kim JW, Kang H, Cha SC

  • KMID: 1551987
  • J Korean Soc Virol.
  • 1998 Sep;28(3):215-224.
Cloning, sequencing and expressing in E. coli of the thymidine kinase (TK) gene of Herpes simplex virus type-1 (HSV-1) strain F was investigated. The TK gene, located in the BamHI...
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Expression of thymidine phosphorylase in cervical neoplasia: correlation with clinicopathological prognostic factors

Choi EK, Kim JW, Lee YJ, Lee JG, Kim DK, Kim YT, Cho NH

  • KMID: 2076203
  • Korean J Obstet Gynecol.
  • 2001 Mar;44(3):550-557.
OBJECTIVES: Angiogenesis is a critical factor in the progression of solid tumors, including cervical cancer. However, the association between the expression of thymidine phosphorylase(TP) and clinicopathological factors has scarcely been...
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Effects of Insulin-like Growth Factor in Peritoneal Fluid of Patients with Endometriosis on the Proliferation of Endometrial Stromal Cells

Kim JG, Suh CS, Kim SH, Choi YM, Moon SY, Lee JY

  • KMID: 1891279
  • Korean J Fertil Steril.
  • 1999 Dec;26(3):331-338.
The purposes of this study were to evaluate the effects of insulin-like growth factor (IGF)s in peritoneal fluid (PF) from patients with and without endometriosis on the proliferation of endometrial...
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Mononuclear Cells Stimulate Leukocyte Adhesion Molecule Expression and Fibronectin Secretion in Mesangial Cells

Ihm CG, Park JK, Hong SP, Lee TW, Kim MJ, Cho BS

  • KMID: 2254962
  • Korean J Nephrol.
  • 1998 May;17(3):376-382.
BACKGROUNDS: The mesangial extracellular matrix expansion appear to be important features of progressive glomerular diseases and the mononuclear cells may play a pivotal role in this process. METHOD: We evaluated...
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Lipocortin 1 mediates the suppressive effects of dexamethasone on CoNinduced proliferative response and nitric oxide production in rat splenic leukocytes

Jang YJ, Park H, Kang SA, Yan SJ, Na DS

  • KMID: 2285163
  • Korean J Physiol Pharmacol.
  • 1997 Feb;1(1):91-96.
Lipocortin 1 has been proposed as a putative mediator of anti-inflammatory actions of glucocorticoids. We investigated the role of lipocortin 1 in the effect of dexamethasone using rat splenic leukocytes. Concanavalin A(ConA; 1-microgram/ml)...
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A Case of G-6-PD Guadalajara

Lee GB, Lee SJ, Kim YJ, Kim SY, Kim HH, Cho B, Lee W

  • KMID: 2278890
  • Korean J Pediatr.
  • 2004 Feb;47(2):210-213.
Glucose-6-phosphate dehydrogenase(G-6-PD) deficiency is a disease that shows hemolytic anemia and jaundice caused by injury of erythrocytes. The gene of G-6-PD has 13 exons and locates in Xq28, and over...
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Thymidine Phosphorylase Expression in Progression of Cervical Lesions: Histological Features and Microvessel Density

Yoon JH, Choi H, Lee SK, Kim SH, Lee JH, Kim SB

  • KMID: 2077520
  • Korean J Obstet Gynecol.
  • 2005 Dec;48(12):2857-2866.
OBJECTIVE: The object of this study was to clarify the association of thymidine phosphorylase (TP) assessed in cancer cells and in stromal cells, with clinico-pathological factors including tumor angiogenesis and...
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