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Letter: Effects of alpha-lipoic Acid on Differentiation of Thyroid Cancer Cells

Jung KH

No abstract available.
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Improvement of Metabolic Syndrom by Alpha-lipoic Acid

Koh EH, Lee WJ, Kim MS, Park JY, Lee KU

  • KMID: 1515269
  • J Korean Soc Endocrinol.
  • 2004 Jun;19(3):267-273.
No abstract available.
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Endothelial Dysfunction in Type 2 Diabetes: Role of Alpha-lipoic Acid, an Antioxidant

Song KH, Park JY

  • KMID: 2177811
  • J Korean Diabetes Assoc.
  • 2002 Aug;26(4):238-241.
No abstract available.
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Response: Effects of alpha-lipoic Acid on Differentiation of Thyroid Cancer Cells

Kim WG, Kim WB

No abstract available.
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Comparison of R(+)-α-lipoic acid exposure after R(+)-α-lipoic acid 200 mg and 300 mg and thioctic acid 600 mg in healthy Korean male subjects

Yoon J, Moon SJ, Lee KO, Yoon SH, Jang IJ, Yu KS, Lee S

Alpha-lipoic acid, a physiological form of thioctic acid, is a strong antioxidant that relieves diabetic neuropathic symptoms. R(+)-α-lipoic acid shows superior antioxidative effects to its racemate. We compared the pharmacokinetics...
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Anti-Inflammatory and Antioxidative Effects of Alpha Lipoic Acid on Cultured Human Sebocytes

Lee WJ, Eun DH, Kim SM, Kim JY, Jang YH, Lee SJ

No abstract available.
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Injections for nutrition and cosmetic purposes: promoted effect vs. objective evidence

Shin HY

The introduction of intravenous nutritional therapy for cosmetic and health purposes in Korea has been controversial. Because it brings ethical problems of off-label prescribing on the basis of low level...
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Effects of Antioxidant Drugs in Rats with Acute Renal Injury

Bae EH, Lee JU, Kim SW

Acute renal failure is mainly caused by ischemia/reperfusion (I/R) injury or nephrotoxic drugs, in which reactive oxygen species (ROS) may play an important role. Therefore, antioxidants are expected to decrease...
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The Effects of Glucocorticoid and alpha-Lipoic Acid on Ischemia-Reperfusion Injury

Lee SS, Chung YJ, Sohn BK, Kim HG, Park SH

  • KMID: 2203714
  • J Korean Soc Plast Reconstr Surg.
  • 2002 May;29(3):205-210.
During revascularization after ischemia, oxygen free radicals and cytotoxic enzymes are released and they have a role in pathogenesis of ischemia-reperfusion injury. Glucocorticoid decreases oxygen free radical formation by inhibition...
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Insulin autoimmune syndrome associated with alpha-lipoic acid in a young woman with no concomitant disease

Lee SB, Lee MY, You JH, Kim SH, Nam JS

Insulin autoimmune syndrome (IAS) is characterized by spontaneous hypoglycemia, extremely high serum insulin levels, and high titers of autoantibodies against endogenous insulin, in the absence of exogenous insulin injection. IAS...
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Suppression of VEGF and STAT3 by Lipoic acid in Experimental Diabetic Rat Retina

Yu SI, Jung HJ, Her DY, Kim HW, Yun IH

  • KMID: 2210949
  • J Korean Ophthalmol Soc.
  • 2007 May;48(5):715-724.
PURPOSE: We evaluated whether lipoic acid as antioxidant could inhibit expression of VEGF and STAT3 in experimental diabetic rat retina. METHODS: Diabetes was induced chemically by injection of streptozotocin in...
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A case of insulin autoimmune syndrome related to alpha-lipoic acid

Chang HJ, Choi HS, Park MY, Leem SM, Jang YS, Park KS, Lee JM

  • KMID: 2257626
  • Korean J Med.
  • 2009 May;76(5):600-604.
Insulin autoimmune syndrome is characterized by spontaneous hypoglycemia, high concentrations of serum immunoreactive insulin, and the presence of autoantibodies to insulin without previous insulin injection. A 71-year-old woman with diabetes,...
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Cytoprotective effects of dihydrolipoic acid and lipoic acid on the oxidative stress in cultured rat cortical neurons

Kim WK

  • KMID: 2285205
  • Korean J Physiol Pharmacol.
  • 1998 Aug;2(4):427-433.
In brain hypoxic-ischemia, an excess release of glutamate and a marked production of reactive oxygen species (ROS) occur in neuronal and non-neuronal cells. The present study investigated the effect of the biological antioxidants...
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Management of Diabetic Peripheral Neuropathy

Kang MS, Kim CH

Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus. The prevalence of neuropathic pain is estimated to occur in about 30-50% of all diabetic patients. Clinical symptoms vary...
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alpha-Lipoic acid reduced weight gain and improved the lipid profile in rats fed with high fat diet

Seo EY, Ha AW, Kim WK

  • KMID: 2313593
  • Nutr Res Pract.
  • 2012 Jun;6(3):195-200.
The purpose of this study was to investigate the effects of alpha-lipoic acid on body weight and lipid profiles in Sprague-Dawley rats fed a high fat diet (HFD). After 4...
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Effects of alpha-lipoic acid on cell proliferation and apoptosis in MDA-MB-231 human breast cells

Na MH, Seo EY, Kim WK

  • KMID: 2392040
  • Nutr Res Pract.
  • 2009 Dec;3(4):265-271.
The role that antioxidants play in the process of carcinogenesis has recently gained considerable attention. alpha-Lipoic acid, a naturally occurring disulfide molecule, is a powerful antioxidant that reportedly exerts beneficial...
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Lipoic Acid Prevents the Changes of Intracellular Lipid Partitioning by Free Fatty Acid

Kim DC, Jun DW, Jang EC, Kim SH, Kim EK, Lee SP, Lee KN, Lee HL, Lee OY, Yoon BC, Choi HS

  • KMID: 2135074
  • Gut Liver.
  • 2013 Mar;7(2):221-227.
BACKGROUND/AIMS: It is suggested that the hepatic lipid composition is more important than lipid quantity in the pathogenesis of non-alcoholic steatohepatitis. We examined whether lipoic acid (LA) could alter intrahepatic...
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Hyperglycemia-induced Activation of Nuclear Transcription Factor kappaB in Cultured Fibroblasts and Endothelial Cells

Kim KH, Kim BC, Lee KS

  • KMID: 2250207
  • Korean J Dermatol.
  • 2003 Apr;41(4):423-428.
BACKGROUND: A common endpoint of hyperglycemia dependent cellular changes is the generation of reactive oxygen intermediates (ROIs) and the presence of elevated oxidative stress. Therefore, oxidative stress is supposed to...
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The Comparison of Efficacy with alpha-lipoic Acid Treatment Methods in Diabetic Polyneuropathy

Lee H, Min KW, Han KA

BACKGROUND: Diabetic neuropathy represents a major health problem, as it is responsible for substantial morbidity, increased mortality, and impaired quality of life. Antioxidant treatment has been shown to prevent nerve...
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Effects of alpha-Lipoic Acid on the Antioxidant System in Prostate Cancer Cells

Choi S, Min K, Choi I, Kang D

PURPOSE: Overproduction of lipid peroxidation byproducts and disturbances in the antioxidant defense system have been implicated in the pathogenesis of several diseases, including prostate cancer. Although several studies have investigated...
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