- HDL Cholesterol Reduction during Rosiglitazone and Fenofibrate Treatment in a Type 2 Diabetes Mellitus Patient with Dyslipidemia
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Im M, Kim M, Lee JK, Chang YH, Lee DY, Hong SI, Lee YY, Hong YJ
- KMID: 1096813
- Korean J Lab Med.
- 2010 Feb;30(1):17-19.
- doi: 10.3343/kjlm.2010.30.1.17
Thiazolidinediones (TZD), which are widely used as insulin sensitizers, and fibrates, which are lipid-lowering drugs, are used in the treatment of dyslipidemia that commonly accompanies diabetes. Several reports suggest elevated... -
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- Beneficial Effects of Thiazolidinediones on Diabetic Nephropathy in OLETF Rats
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Lee MY, Lee EY, Lee BJ, Won CS, Koh JH, Shin JY, Shin YG, Cho BP, Chung CH
- KMID: 1779535
- Yonsei Med J.
- 2007 Apr;48(2):301-307.
- doi: 10.3349/ymj.2007.48.2.301
PURPOSE: Diabetic nephropathy is the most serious of complications in diabetes mellitus. Thiazolidinedione (TZD) is thought to ameliorate diabetic nephropathy; however, the mechanism underlying this effect has not been elucidated.... -
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- Short Insulin Tolerance Test Can Determine the Effects of Thiazolidinediones Treatment in Type 2 Diabetes
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Lee MY, Koh JH, Nam SM, Jung PM, Sung JK, Kim SY, Shin JY, Shin YG, Chung CH
- KMID: 1782937
- Yonsei Med J.
- 2008 Dec;49(6):901-908.
- doi: 10.3349/ymj.2008.49.6.901
PURPOSE: The short insulin tolerance test is a simple and reliable method of estimating insulin sensitivity. This study was designed to compare the insulin sensitizing effects of thiazolidinediones (TZDs) on... -
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- Serial Micro-CT Assessment of the Therapeutic Effects of Rosiglitazone in a Bleomycin-Induced Lung Fibrosis Mouse Model
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Choi EJ, Jin GY, Bok SM, Han YM, Lee YS, Jung MJ, Kwon KS
- KMID: 1731048
- Korean J Radiol.
- 2014 Aug;15(4):448-455.
- doi: 10.3348/kjr.2014.15.4.448
OBJECTIVE: The aim of this study was to assess the therapeutic effects of rosiglitazone with serial micro-CT findings before and after rosiglitazone administration in a lung fibrosis mouse model induced... -
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- Long-Term Effects of Rosiglitazone on the Progressive Decline in Renal Function in Patients With Type 2 Diabetes
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Kim MK, Ko SH, Baek KH, Ahn YB, Yoon KH, Kang MI, Lee KW, Song KH
- KMID: 1717946
- Korean J Intern Med.
- 2009 Sep;24(3):227-232.
- doi: 10.3904/kjim.2009.24.3.227
BACKGROUND/AIMS: Thiazolidinediones reduce urinary albumin excretion and may prevent the development of renal injury. We evaluated the long-term effects of rosiglitazone on the progression of renal dysfunction in patients with... -
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- Rosiglitazone, a Peroxisome Proliferator-Activated Receptor-gamma Agonist, Restores Alveolar and Pulmonary Vascular Development in a Rat Model of Bronchopulmonary Dysplasia
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Lee HJ, Lee YJ, Choi CW, Lee JA, Kim EK, Kim HS, Kim BI, Choi JH
- KMID: 1779892
- Yonsei Med J.
- 2014 Jan;55(1):99-106.
- doi: 10.3349/ymj.2014.55.1.99
PURPOSE: We tested whether rosiglitazone (RGZ), a peroxisome proliferator-activated receptor-gamma agonist, can restore alveolar development and vascular growth in a rat model of bronchopulmonary dysplasia (BPD). MATERIALS AND METHODS: A rat... -
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- Reduced Food Intake is the Major Contributor to the Protective Effect of Rimonabant on Islet in Established Obesity-Associated Type 2 Diabetes
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Jin SM, Oh BJ, Lee S, Choi JM, Yang SJ, Park SW, Kim KW, Kim JH, Park CY
- KMID: 1793159
- Yonsei Med J.
- 2013 Sep;54(5):1127-1136.
- doi: 10.3349/ymj.2013.54.5.1127
PURPOSE: Although the presence of cannabinoid type 1 (CB1) receptor in islets has been reported, the major contributor to the protective effect of rimonabant on islet morphology is unknown. We... -
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- Risk of Bladder Cancer among Patients with Diabetes Treated with a 15 mg Pioglitazone Dose in Korea: A Multi-Center Retrospective Cohort Study
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Jin SM, Song SO, Jung CH, Chang JS, Suh S, Kang SM, Jung I, Park CY, Kim JH, Cho JH, Lee BW
- KMID: 1789981
- J Korean Med Sci.
- 2014 Feb;29(2):238-242.
- doi: 10.3346/jkms.2014.29.2.238
It has not yet been determined whether chronic exposure to relatively low doses of pioglitazone increases risk of bladder cancer. We aimed to assess the risk of bladder cancer associated... -
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- 5-(4-Hydroxy-2,3,5-trimethylbenzylidene) thiazolidine-2,4-dione attenuates atherosclerosis possibly by reducing monocyte recruitment to the lesion
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Choi JH, Park JG, Jeon HJ, Kim MS, Lee MR, Lee MN, Sonn S, Kim JH, Lee MH, Choi MS, Park YB, Kwon OS, Jeong TS, Lee WS, Shim HB, Shin DH, Oh GT
- KMID: 1022122
- Exp Mol Med.
- 2011 Aug;43(8):471-478.
- doi: 10.3858/emm.2011.43.8.053
A variety of benzylidenethiazole analogs have been demonstrated to inhibit 5-lipoxygenase (5-LOX). Here we report the anti-atherogenic potential of 5-(4-hydroxy-2,3,5-trimethylbenzylidene) thiazolidin-2,4-dione (HMB-TZD), a benzylidenethiazole analog, and its potential mechanism of... -
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