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Toxic Epidermal Necrolysis Induced by the Topical Carbonic Anhydrase Inhibitors Brinzolamide and Dorzolamide

Chun JS, Yun SJ, Lee JB, Kim SJ, Won YH, Lee SC

Brinzolamide and dorzolamide are highly specific topical carbonic anhydrase inhibitors (CAIs). They lower intraocular pressure (IOP) by reducing the rate of aqueous humour formation without serious side effects. Although systemic...
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Meloxicam-Induced Rhabdomyolysis in the Context of an Acute Ross River Viral Infection

Al Kindi M, Limaye V, Hissaria P

Acute rhabdomyolysis is a clinical and laboratory syndrome resulting from the breakdown of skeletal muscle, with the release of intracellular contents into the circulatory system, which can cause potentially lethal...
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Expression of cytokeratin 10, 16 and 17 as biomarkers differentiating odontogenic keratocysts from dentigerous cysts

Kim JM, Choi SY, Kim CS

OBJECTIVES: Odontogenic keratocysts (OKCs) have a tendency to recur and possess an aggressive nature. the aim of the present study was to evaluate cytokeratin (CK) expression patterns as a method...
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Quantitation of meloxicam in the plasma of koalas (Phascolarctos cinereus) by improved high performance liquid chromatography

Kimble B, Li KM, Govendir M

An improved method to determine meloxicam (MEL) concentrations in koala plasma using reversed phase high performance liquid chromatography equipped with a photo diode array detector was developed and validated. A...
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Up-regulation of cyclooxygenase-2-derived prostaglandin E2 in colon cancer cells resistant to 5-fluorouracil

Choi CH, Lee TB, Lee YA, Choi S, Kim KJ

PURPOSE: It has been suggested that constitutive up-regulation of cyclooxygenase (COX)-2 is associated with resistance to apoptosis, increased angiogenesis, and increased tumor invasiveness in various cancers including colon cancer. There...
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In vitro effects of meloxicam on the number, Foxp3 expression, production of selected cytokines, and apoptosis of bovine CD25+CD4+ and CD25-CD4+ cells

Maslanka T, Jaroszewski JJ

The purpose of this study was to evaluate the effect of meloxicam (MEL) on selected immune parameters of bovine CD25highCD4+, CD25lowCD4+, and CD25-CD4+ cells. Peripheral blood mononuclear cells (PBMCs) collected...
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Cyclooxygenase-2 Inhibitor Reduces Hepatic Stiffness in Pediatric Chronic Liver Disease Patients Following Kasai Portoenterostomy

Chang HK, Chang EY, Ryu S, Han SJ

PURPOSE: The purpose of this study was to define the role of cyclooxygenase-2 inhibitors (COX-2i) in reducing hepatic fibrosis in pediatric patients with chronic liver disease. MATERIALS AND METHODS: From September...
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Concentration of Non-Steroidal Anti-Inflammatory Drugs in the Pelvic Floor Muscles: An Experimental Comparative Rat Model

Chin HY, Changchien E, Lin MF, Chiang CH, Wang CJ

PURPOSE: The aim of this study is to explore non-steroid anti-inflammation drugs (NSAIDs) potency for pelvic floor muscle pain by measuring local concentration in a rat model. MATERIALS AND METHODS: We...
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Risk Factors of Drug Interaction between Warfarin and Nonsteroidal Anti-Inflammatory Drugs in Practical Setting

Choi KH, Kim AJ, Son IJ, Kim KH, Kim KB, Ahn H, Lee EB

Nonsteroidal anti-inflammatory drugs (NSAIDs) are known to interact with the oral anticoagulant warfarin and can cause a serious bleeding complication. In this study, we evaluated the risk factors for international...
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Efficacy of Combination of Meloxicam and Pregabalin for Pain in Knee Osteoarthritis

Ohtori S, Inoue G, Orita S, Takaso M, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzkuki M, Nakamura J, Kubota G, Sakuma Y, Oikawa Y, Toyone T, Inage K, Sainoh T, Yamauchi K, Takahashi

PURPOSE: Osteoarthritic pain is largely considered to be inflammatory pain. Sensory nerve fibers innervating the knee have been shown to be significantly damaged in rat models of knee osteoarthritis (OA)...
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Osteochondrodysplasia in three Scottish Fold cats

Chang J, Jung J, Oh S, Lee S, Kim G, Kim H, Kweon O, Yoon J, Choi M

This report explains typical radiographic features ofScottish Fold osteochondrodysplasia. Three Scottish Foldcats suffering from lameness were referred to theVeterinary Medical Teaching Hospital, Seoul NationalUniversity, Korea. Based on the breed predisposition,history,...
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Preventive Efficacy and Safety of Rebamipide in Nonsteroidal Anti-Inflammatory Drug-Induced Mucosal Toxicity

Kim JH, Park SH, Cho CS, Lee ST, Yoo WH, Kim SK, Kang YM, Rew JS, Park YW, Lee SK, Lee YC, Park W, Lee DH

  • KMID: 1792359
  • Gut Liver.
  • 2014 Jul;8(4):371-379.
BACKGROUND/AIMS: The use of proton pump inhibitors or misoprostol is known to prevent the gastrointestinal complications of nonsteroidal anti-inflammatory drugs (NSAIDs). Rebamipide is known to increase the mucosal generation of...
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