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Critical Appraisal of SCAST Study

Kim HY

  • KMID: 2288726
  • Korean J Stroke.
  • 2012 Apr;14(1):52-54.
No abstract available.
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The Effect of High-Dose Valsartan on Left Ventricular Function Following Primary Percutaneous Coronary Intervention

Park TH

No abstract available.
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Systemic drug therapy and restenosis after drug-eluting stent implantation

Han KR

  • KMID: 2305860
  • Korean J Med.
  • 2008 Apr;74(4):366-367.
Until now restenosis is one of the most important issues after stent implantation. Use of systemic drug therapy to inhibit post-stent restenosis has been largely unsuccessful. Drug-eluting stents (DES) have...
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A Case of Spontaneous Intramural Hematoma of the Esophagus

Lee CH, Jung HG, Kim DH

  • KMID: 2084628
  • Korean J Gastrointest Endosc.
  • 2010 May;40(5):309-311.
Spontaneous intramural hematoma of the esophagus is a very rare disease. Varying degrees of submucosal rupture of the esophagus are caused by intramural hematoma of the esophagus. The causative factors...
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Spontaneous Spinal Epidural Hematoma in a Patient on Cilostazol

Baek SH, Lee HS, Kang JH, Shin J, Lee H, Kim I, Yang SJ, Kim JS, Shin DI, Lee SH, Lee SS

  • KMID: 2288706
  • Korean J Stroke.
  • 2012 Dec;14(3):170-172.
Cilostazol is a phosphodiesterase inhibitor that has been shown to have similar efficacy in stroke prevention but fewer hemorrhagic events compared with aspirin. We report a case of spontaneous spinal...
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Mutagenic Assessment of Olmesartan Cilexetil by Bacterial Mutation Assay

Kim JW, Ahn I, Ryu SH, Jeon HR, Lee BS, Kim KB

  • KMID: 2317838
  • Toxicol Res.
  • 2013 Sep;29(3):217-219.
Hypertension is a serious health problem due to high frequency and concomitant other diseases including cardiovascular and renal dysfunction. Olmesartan cilexetil is a new antihypertensive drug associated with angiotensin II...
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The Clinical Effects of Cilostazol on Atherosclerotic Vascular Disease

Park JS, Kim YJ

Cilostazol inhibits phosphodiesterase III (PDE III), which is predominantly distributed to and regulates physiologic responses in platelets, cardiac muscle cells, vascular smooth muscle cells, and adipose cells. Clinically, it is...
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Current Knowledge of Peripheral Artery Disease

Choi D

  • KMID: 2263730
  • Korean J Med.
  • 2011 Oct;81(4):444-447.
Peripheral artery disease (PAD) is defined as atherosclerotic disease of infrarenal aorta or arteries of the lower extremities. PAD is a frequent but underdiagnosed and undertreated disease with substantial cardiovascular...
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Current Management of Peripheral Arterial Disease

Choi SH

Peripheral arterial disease (PAD) is defined as atherosclerotic disease of infrarenal aorta and arteries of the lower extremities. PAD is a frequent but underdiagnosed and undertreated disease with substantial cardiovascular...
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Very Late Stent Thrombosis due to Neointimal Rupture After Paclitaxel-Eluting Stent Implantation

Kee WJ, Jeong MH, Jang SY, Lee MG, Park KH, Sim DS, Hong YJ, Kim JH, Ahn Y, Kang JC

We report our experience of very late stent thrombosis (VLST) in a young male patient who underwent implantation of two paclitaxel-eluting stents (PES) six years ago. The patient was compliant...
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Cilostazol Attenuates 4-hydroxynonenal-enhanced CD36 Expression on Murine Macrophages via Inhibition of NADPH Oxidase-derived Reactive Oxygen Species Production

Yun MR, Park HM, Seo KW, Kim CE, Yoon JW, Kim CD

Although anti-atherogenic effects of cilostazol have been suggested, its effects on the expression of SR in macrophages are unclear. This study investigated the role of cilostazol on CD36 expression...
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Cilostazol Reduces PAC-1 Expression on Platelets in Ischemic Stroke

Lee SY, Kang MJ, Cha JK

BACKGROUND AND PURPOSE: Cilostazol, a phosphodiesterase III inhibitor, is known to be a useful antiplatelet agent that inhibits the progression of atherosclerosis in ischemic stroke. This study investigated the effects...
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A Case of Neonate with Acute Renal Failure after Maternal Treatment with Angiotensin II Receptor Blocker

Ra JJ, Eun HS, Lee SM, Park MS, Namgung R, Lee C, Park KI

  • KMID: 2280895
  • Korean J Perinatol.
  • 2012 Dec;23(4):286-291.
Hypertension is common medical problem encountered during pregnancy. However medication administered for maternal hypertension may cause fetal or neonatal complications. Angiotensin converting enzyme inhibitor or angiotensin II receptor blocker are...
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The Effect of an Angiotensin Receptor Blocker on Arterial Stiffness in Type 2 Diabetes Mellitus Patients with Hypertension

Kim JH, Oh SJ, Lee JM, Hong EG, Yu JM, Han KA, Min KW, Son HS, Chang SA

BACKGROUND: Hypertension and type 2 diabetes mellitus are major risk factors for cardiovascular disease. This study analyzed the changes in central aortic waveforms and pulse wave velocity as well as...
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Association Between Carotid Artery Stiffness and Headache Following Cilostazol Use in Cerebral Infarction Patients

Oh ES, Kim DH, Lee JH, Ku BJ, Park JH, Kim J

  • KMID: 2065663
  • J Korean Neurol Assoc.
  • 2008 May;26(2):118-122.
BACKGROUND: Cilostazol leads to inhibition of platelet aggregation and to vasodilatation. It is widely used for the secondary prevention of cerebral infarction. However, headache is a well-known adverse effect of...
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Antiplatelet Therapy for Secondary Stroke Prevention: 2012 Focused Update of Korean Clinical Practice Guidelines for Stroke

Park TH, Kim MK, Oh HG, Oh MS, Yu KH, Hong KS, Bae HJ, Kwon SU, Rha JH, Heo JH, Oh CW, Lee BC, Yoon BW

  • KMID: 2288717
  • Korean J Stroke.
  • 2012 Apr;14(1):1-5.
Writing Committee of Korean clinical practice guidelines for secondary prevention of stroke has reviewed recent randomized controlled trials of cilostazol published after the first edition of Korean clinical practice guidelines...
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HO-1 Induced by Cilostazol Protects Against TNF-alpha-associated Cytotoxicity via a PPAR-gamma-dependent Pathway in Human Endothelial Cells

Park SY, Bae JU, Hong KW, Kim CD

A large body of evidence has indicated that induction of endogenous antioxidative proteins seems to be a reasonable strategy for delaying the progression of cell injury. In our previous study,...
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Synergistic Efficacy of Concurrent Treatment with Cilostazol and Probucol on the Suppression of Reactive Oxygen Species and Inflammatory Markers in Cultured Human Coronary Artery Endothelial Cells

Park SY, Lee JH, Shin HK, Kim CD, Lee WS, Rhim BY, Shin YW, Hong KW

In the present study, we aimed to identify the synergistic effects of concurrent treatment of low concentrations of cilostazol and probucol to inhibit the oxidative stress with suppression of inflammatory...
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Cilostazol Inhibits Vascular Smooth Muscle Cell Proliferation and Reactive Oxygen Species Production through Activation of AMP-activated Protein Kinase Induced by Heme Oxygenase-1

Kim JE, Sung JY, Woo CH, Kang YJ, Lee KY, Kim HS, Kwun WH, Choi HC

Cilostazol is a selective inhibitor of phosphodiesterase 3 that increases intracellular cAMP levels and activates protein kinase A, thereby inhibiting vascular smooth muscle cell (VSMC) proliferation. We investigated whether AMP-activated...
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Effects of ATP and LTC4 on hypoxic pulmonary vasoconstriction in isolated rat lungs

Rho JY, Shin HY, Kim HC, Lee JW, Kim SD

BACKGROUND: Hypoxic pulmonary vasoconstriction (HPV) is unique to pulmonary circulation but the mechanism remains elusive. Red blood cells (RBCs) are known to augment HPV and to release more ATP as...
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