- Telomerase activity in pterygeal and normal conjunctival epithelium
-
Park TK, Jin KH
- KMID: 754280
- Korean J Ophthalmol.
- 2000 Dec;14(2):85-89.
- doi: 10.3341/kjo.2000.14.2.85
All pterygia have similar histologic features of solar degeneration seen in the skin such as acanthosis, keratosis, or hyperkeratosis. Although the pathogenesis of pterygia is still unclear, an association with... -
- CITED
-
- Close
- SHARE
-
- Close
- Telomerase activity: a potential marker of bladder transitional cell carcinoma in bladder washes
-
Yang SC, Lee DH, Hong SJ, Chung BH, Kim IY
- KMID: 699944
- Yonsei Med J.
- 1997 Jun;38(3):155-159.
- doi: 10.3349/ymj.1997.38.3.155
The enzyme telomerase maintains a constant telomere length in immortalized cells, allowing unlimited cell proliferation. Almost all cancer cells express telomerase activity. However, little data is available regarding... -
- CITED
-
- Close
- SHARE
-
- Close
- Immortalization of human embryonic fibroblasts by overexpression of c-myc and simian virus 40 large T antigen
-
Kim HS, Shin JY, Yun JY, Ahn DK, Lee JY
- KMID: 1457544
- Exp Mol Med.
- 2001 Dec;33(4):293-298.
SV40 large T antigen, a viral oncoprotein, is known to immortalize human diploid fibroblast by soaking up cellular RB and p53, but its frequency is extremely low. Additional genetic alteration... -
- CITED
-
- Close
- SHARE
-
- Close
- Change of telomerase activity in rectal cancer with chemoradiation therapy
-
Kim HR, Kim YJ, Kim HJ, Kim SK, Lee JH
- KMID: 648118
- J Korean Med Sci.
- 2000 Apr;15(2):167-172.
- doi: 10.3346/jkms.2000.15.2.167
Telomerase, an enzyme associated with cellular immortality, is expressed by most malignant cells and is inactive in most normal somatic cells, with the exception of proliferative stem cells, germ cells... -
- CITED
-
- Close
- SHARE
-
- Close
- The mutational landscape of hepatocellular carcinoma
-
Lee JS
- KMID: 2351021
- Clin Mol Hepatol.
- 2015 Sep;21(3):220-229.
- doi: 10.3350/cmh.2015.21.3.220
The development of hepatocellular carcinoma (HCC) is a complex process, and HCC arises from the accumulation of multiple genetic alterations leading to changes in the genomic landscape. Current advances in... -
- CITED
-
- Close
- SHARE
-
- Close
- Stemness Evaluation of Mesenchymal Stem Cells from Placentas According to Developmental Stage: Comparison to Those from Adult Bone Marrow
-
Sung HJ, Hong SC, Yoo JH, Oh JH, Shin HJ, Choi IY, Ahn KH, Kim SH, Park Y, Kim BS
- KMID: 2157843
- J Korean Med Sci.
- 2010 Oct;25(10):1418-1426.
- doi: 10.3346/jkms.2010.25.10.1418
This study was done to evaluate the stemness of human mesenchymal stem cells (hMSCs) derived from placenta according to the development stage and to compare the results to those from... -
- CITED
-
- Close
- SHARE
-
- Close
- Dedifferentiation of conditionally immortalized hepatocytes with long-term in vitro passage
-
Kim BH, Sung SR, Choi EH, Kim YI, Kim KJ, Dong SH, Kim HJ, Chang YW, Lee JI, Chang R
- KMID: 927131
- Exp Mol Med.
- 2000 Mar;32(1):29-37.
The rat hepatocytes were immortalized using a temperature-sensitive mutant of SV40 large T antigen (tsT) to develop as a possible substitute for primary hepatocytes. Four rat hepatocyte lines that have... -
- CITED
-
- Close
- SHARE
-
- Close
- Alterations of proliferative and differentiation potentials of human embryonic stem cells during long-term culture
-
Park YB, Kim YY, Oh SK, Chung SG, Ku SY, Kim SH, Choi YM, Moon SY
- KMID: 1103593
- Exp Mol Med.
- 2008 Feb;40(1):98-108.
- doi: 10.3858/emm.2008.40.1.98
Human embryonic stem cells (hESCs) are considered to be able to stably maintain their characteristics in vitro for prolonged periods, but we had previously encountered changes in proliferative ability and... -
- CITED
-
- Close
- SHARE
-
- Close
- Role of STAT3 as a Negative Regulator in Mac2- Binding Protein Expression
-
Park YP, Kim JT, Yang Y, Lim JS, Yoon DY, Kim JW, Lee HG
- KMID: 854872
- Korean J Lab Med.
- 2008 Jun;28(3):230-238.
- doi: 10.3343/kjlm.2008.28.3.230
BACKGROUND: Mac-2 binding protein (Mac-2BP) is a secreted glycoprotein from the culture fluid of several human cancer cells, especially breast, lung, and gastric cells. Mac-2BP plays a role in immune... -
- CITED
-
- Close
- SHARE
-
- Close
