- Apoptosis of Fas Expressed Target Cells Induced by Cytotoxic T Lymphocytes
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Kim SH, Kim SY
- KMID: 1548225
- Korean J Immunol.
- 1997 Jun;19(2):245-262.
Cytotoxic T lymphocytes (CTL) playing an important role in e cell-mediated immune response kill the target cells by the special contact-dependent mechanism. It has been known that CTL and NK... -
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- Proliferation of CD4(+)CD25(high+)Foxp3(+) regulatory T lymphocytes in ex vivo expanded ascitic fluid from primary and recurrent ovarian carcinoma
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Lee SW, Kim YM, Lee HY, Kim DY, Kim JH, Nam JH, Kim YT
- KMID: 2173510
- J Gynecol Oncol.
- 2010 Mar;21(1):38-44.
- doi: 10.3802/jgo.2010.21.1.38
OBJECTIVE: Regulatory T lymphocytes evoke the immune tolerance by suppressing and inactivating cytotoxic T lymphocytes. The objective of this study was to compare the proportion of regulatory T lymphocytes, precisely... -
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- A Case of Subcutaneous Panniculitic T-cell Lymphoma
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Eim JJ, Kim YH, Joh GY, Kim KH
- KMID: 2163998
- Ann Dermatol.
- 2000 Dec;12(4):275-279.
- doi: 10.5021/ad.2000.12.4.275
We herein report a case of subcutaneous panniculitic T-cell lymphoma which occurred in a 48-year-old Korean woman. Her disease presented as multiple subcutaneous nodules on the arms, legs, and abdomen,... -
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- Nucleoprotein vaccine induces cross-protective cytotoxic T lymphocytes against both lineages of influenza B virus
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Lee SY, Kang JO, Chang J
- KMID: 2438964
- Clin Exp Vaccine Res.
- 2019 Jan;8(1):54-63.
- doi: 10.7774/cevr.2019.8.1.54
PURPOSE: The influenza B virus diverges into two antigenically distinct lineages: B/Yamagata and B/Victoria. Influenza B is the dominant circulating virus during some influenza seasons, and recent data demonstrated that... -
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- Enhanced Anti-tumor Reactivity of Cytotoxic T Lymphocytes Expressing PD-1 Decoy
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Shin JH, Park HB, Choi K
- KMID: 2168054
- Immune Netw.
- 2016 Apr;16(2):134-139.
- doi: 10.4110/in.2016.16.2.134
Programmed death-1 (PD-1) is a strong negative regulator of T lymphocytes in tumor-microenvironment. By engaging PD-1 ligand (PD-L1) on tumor cells, PD-1 on T cell surface inhibits anti-tumor reactivity of... -
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- Primary T-cell Lymphoma of the Thyroid Associated with Hashimoto's Thyroiditis, Histologically Mimicking MALT-Lymphoma
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Kim NR, Ko YH, Lee YD
- KMID: 1778048
- J Korean Med Sci.
- 2010 Mar;25(3):481-484.
- doi: 10.3346/jkms.2010.25.3.481
Most of thyroid lymphomas are B-lineage, and T-cell lymphomas are rare. Here, we report a case of primary thyroid T-cell lymphoma associated with Hashimoto's thyroiditis. A 48-yr-old woman presented with... -
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- Changes of Tumor-infiltrating Lymphocytes in Breast Cancer after Neoadjuvant Chemotherapy
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Shin HJ, Kang HJ, Choi JW, Min SK, Ko EY, Kim LS
- KMID: 2004325
- J Korean Surg Soc.
- 2005 Nov;69(5):367-373.
PURPOSE: Neoadjuvant chemotherapy for breast cancer creates new possibilities for the analysis of biological factors in the tumor and/or host, which may play a role in the response to treatment.... -
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- Morphologic Evidence of Anti-Tumor Specificity of T Cells Activated by Denritic Cells Derived from Peripheral Blood Mononuclear Cells of Thyroid Cancer Patients
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Lee DH
- KMID: 2011158
- Korean J Physiol Pharmacol.
- 2012 Aug;16(4):243-247.
- doi: 10.4196/kjpp.2012.16.4.243
Recent studies suggest that immunization with autologous dendritic cells (DCs) results in protective immunity and rejection of established tumors in various human malignancies. The purpose of this study is to... -
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- Cellular immunotherapy using dendritic cells against multiple myeloma
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Nguyen-Pham TN, Lee YK, Lee HJ, Kim MH, Yang DH, Kim HJ, Lee JJ
- KMID: 2251967
- Korean J Hematol.
- 2012 Mar;47(1):17-27.
- doi: 10.5045/kjh.2012.47.1.17
Cellular therapy with dendritic cells (DCs) is emerging as a useful immunotherapeutic tool to treat multiple myeloma (MM). DC-based idiotype vaccination was recently suggested to induce idiotype-specific immune responses in... -
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- Flow cytometric analysis of lymphocyte subset in Korean Air forces pilots
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Park WS, Park SH
- KMID: 1554178
- Korean J Aerosp Environ Med.
- 1998 Jun;8(2):162-168.
Major lymphocyte subsets were quantitated using immunofluorescence staining and flow cytometric analysis in Korea Air Force pilots undergoing continuous training and intensive situation both physically and psychologically. Total 197 subjects... -
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- Generation of Renal Cell Carcinoma-specific CD4+ /CD8+ T Cells Restricted by an HLA-39 from a RCC Patient Vaccinated with GM-CSF Gene-Transduced Tumor Cells
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Jun DY, Moutner J, Jaffee E
- KMID: 2150574
- Immune Netw.
- 2003 Jun;3(2):96-102.
- doi: 10.4110/in.2003.3.2.96
BACKGROUND: Granulocyte-macrophage colony-stimulating factor (GM-CSF) gene- transduced tumor cell vaccines induce very potent systemic anti-tumor immunity in preclinical and clinical models. Our previous phase I clinical trial in patients with... -
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- Immumoadjuvant Activitiy of Korean Mistletoe Extract ( Viscum album coloratum ) to Enhance Humoral and Cellular Immune Response
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Yoon TJ, Yoo YC, Kang TB, Song SK, Doo MS, Kim JB
- KMID: 1550797
- Korean J Immunol.
- 1999 Mar;21(1):63-70.
Immunoadjuvant activities of the extract (KM-110) from Korean mistletoe ( Viscum album coloratum) on the induction of humoral and cellular responses against Keyhole limpet hemocyanim (KLH) as an antigen and... -
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- Induction of Cytotoxic T Lymphocytes by Dendritic Cells Pulsed with Murine Leukemic Cell RNA
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Jung CW, Kwon JH, Seol JG, Park WH, Hyun JM, Kim ES, Kim ST, Lee SJ, Kim BK, Lee YY
- KMID: 1563283
- Korean J Hematol.
- 2001 Aug;36(3):223-231.
BACKGROUND: This study was done to assess the feasibility of dendritic cell generation from murine bone marrow and the efficacy of dendritic cells pulsed with total RNA to induce specific... -
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- Selective addition of CXCR3+CCR4-CD4+ Th1 cells enhances generation of cytotoxic T cells by dendritic cells in vitro
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Yoon SH, Yun SO, Park JY, Won HY, Kim EK, Sohn HJ, Cho HI, Kim TG
- KMID: 1123463
- Exp Mol Med.
- 2009 Mar;41(3):161-170.
- doi: 10.3858/emm.2009.41.3.019
Increasing importance is being given to the stimulation of Th1 response in cancer immunotherapy because its presence can shift the direction of adaptive immune responses toward protective immunity. Based on... -
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- Anti-tumor Cytotoxicity of Allogeneic Neuroblastoma Tumor Antigen-loaded Dendiritic Cells
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Park HJ, Shin HY, Ahn HS
- KMID: 2083511
- Korean J Hematol.
- 2007 Jun;42(2):136-145.
- doi: 10.5045/kjh.2007.42.2.136
BACKGROUND: Despite of aggressive treatments, the long-term survival rate is about 30% in stage 4 neuroblastoma (NBL). Recently, dendritic cell (DC)-based immunotherapy is emerging as a promising tool in cancer... -
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- Induction of Autologous Cancer-specific Cytotoxic T Lymphocytes using Dendritic Cells from Patients with Medullary Thyroid Carcinoma
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Kim JH
- KMID: 2375913
- Korean J Endocr Surg.
- 2006 Dec;6(2):55-62.
- doi: 10.16956/kjes.2006.6.2.55
PURPOSE: Recent studies suggest that immunization with autologous dendritic cells (DCs) results in a protective immunity and a rejection of established tumors for various human malignancies. It has been reported... -
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- Characterization of the nover late T cell activation proteins, 519 and 520
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Lee DY, Krensky AM
- KMID: 2104055
- J Korean Pediatr Soc.
- 1993 Mar;36(3):409-416.
The late T cell activation gene, 519, is expressed in antigen specific, growth factor dependent T cell lines and clones but not in T or B cell tumors, other hematopoietic... -
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- Glioma Stem Cell-Targeted Dendritic Cells as a Tumor Vaccine Against Malignant Glioma
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Ji B, Chen Q, Liu B, Wu L, Tian D, Guo Z, Yi W
- KMID: 1776923
- Yonsei Med J.
- 2013 Jan;54(1):92-100.
- doi: 10.3349/ymj.2013.54.1.92
PURPOSE: Cancer stem cells have recently been thought to be closely related to tumor development and reoccurrence. It may be a promising way to cure malignant glioma by using glioma... -
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- A Study for Apoptosis and Its Mechanism of Allogeneic Activated T Lymphocytes Induced by Mouse Liver Immature Dendritic Cells
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Lee YC, Kim JJ, Park HR, Lee S, Woo YM, Cho MH, Kim JS, Lee BH
- KMID: 2209905
- J Korean Surg Soc.
- 2004 Jan;66(1):1-4.
PURPOSE: Mouse liver nonparenchymal cells play an important role in the development of active apoptosis in graft- infiltrating cytotoxic T lymphocytes, and this apoptosis can be an explanation for liver... -
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- A Study on the Epidermis Undergoing Apoptosis After Bone Marrow Transplantation
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Lee SY, Park BS, Bae SH, Jin YJ, Yoon S, Yoo KS, Lim YJ, Yoo YH
- KMID: 2092659
- Korean J Anat.
- 1998 Aug;31(4):581-594.
GVHD (Graft-versus-Host Disease) results from the cytotoxic T lymphocytes from the bone marrow recognizing the recipient's minor histocompatibility antigens. In experimental murine models, either CD4+ or CD8+ T-cell subsets can... -
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