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Enzymology of Protein Methylation

Paik WK, Kim S

No abstract available.
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Noninvasive Measurement of Gastric Accommodation by SPECT

Kim DY, Camilleri

  • KMID: 1758670
  • Korean J Intern Med.
  • 2002 Mar;17(1):1-6.
No abstract available.
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Recent progress in lysosomal alpha-mannosidase and its deficiency

Sun H, Wolfe JH

  • KMID: 755109
  • Exp Mol Med.
  • 2001 Mar;33(1):1-7.
Lysosomal alpha-mannosidase (EC 3.2.1.24) is a major exoglycosidase in the glycoprotein degradation pathway. A deficiency of this enzyme causes the lysosomal storage disease, alpha-mannosidosis, which has been described in humans,...
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Experimental Atherosclerosis in Pigs

Lee KT

No abstract available.
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Type 2 Herpes Simplex Virus Infections

Oh JO

No abstract available.
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Development of inhibitors of pyrimidine metabolism

Cha S

Benzylacyclouridines were developed as specific and potent competitive inhibitors of uridine phosphorylase with Ki values in the nanomolar range. These compounds have no activity against thymidine phosphorylase, uridine kinase,...
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Regulation of Glomerular Endothelial Cell Proteoglycans by Glucose

Ha TS, Duraisamy , Faulkner J, Kasinath B

The presence of heparan sulfate proteoglycan (HSPG) in anionic sites in the lamina rara interna of glomerular basement membrane suggests that the proteoglycan may be deposited by the glomerular endothelial...
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Relationship of change in body mass to blood pressure among children in Korea and black and white children in the United States

Suh I, Webber LS, Cutler JA, Berenson G

Body mass is a major factor in determining blood pressure levels in children. We compared associations of body mass with blood pressure in 121 white and 91 black children in...
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In vivo characterization of the integrin beta3 as a receptor for Hantaan virus cellular entry

Song JW, Song KJ, Baek LJ, Frost B, Poncz M, Park KS

  • KMID: 755750
  • Exp Mol Med.
  • 2005 Apr;37(2):121-127.
Binding of viruses to cell surface molecules is an essential step in viral infection. In vitro studies suggested that the alpha v beta3 integrin receptor is the epithelial cell receptor...
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Serum concentrations of soluble 4-1BB and 4-1BB ligand correlated with the disease severity in rheumatoid arthritis

Jung HW, Choi SW, Choi JI, Kwon BS

  • KMID: 755660
  • Exp Mol Med.
  • 2004 Feb;36(1):13-22.
Rheumatoid arthritis (RA) is a multifactorial autoimmune disease whose etiopathogenesis is not well understood. Although soluble (s) forms of 4-1BB (s4-1BB) and 4-1BB legand (s4-1BBL) have been detected in the...
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Biomarkers in chemoprevention for upper aerodigestive tract tumors

Shin DM, Ro JY, Hong WK

A chemopreventive approach to cancers of the upper aerodigestive tract (including those of head and neck and lung) to reduce the incidence and mortality rates for these cancers has become...
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Evidence that the fully assembled capsid of Leishmania RNA virus 1-4 possesses catalytically active endoribonuclease activity

Ro YT, Kim EJ, Lee HI, Saiz M, Jr RC, Patterson

  • KMID: 1380209
  • Exp Mol Med.
  • 2004 Apr;36(2):145-156.
In this study, Leishmania RNA virus 1-4 (LRV1-4) particles purified from host Leishmania guyanensis promastigotes were examined for capsid endoribonuclease. Temperature optimum for the endoribonulease activity was found to be...
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Characterization of an unusual variant mRNA of human lysosomal alpha-mannosidase

Sun H, Wolfe JH

  • KMID: 755097
  • Exp Mol Med.
  • 2000 Dec;32(4):187-192.
Lysosomal alpha-mannosidase (EC 3.2.1.24) is an exoglycosidase in the glycoprotein degradation pathway and is encoded by a 3.0 kb cDNA. A 2.3 kb cDNA from a minor species...
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A randomized controlled trial to motivate worksite fecal occult blood testing. Lee CY

Lee CY

Colorectal cancer is second only to lung cancer as a cause of cancer death in the United States. Studies have shown that fecal occult blood (FOB) tests are effective in...
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Selective inhibition of glutamate uptake by mercury in cultured mouse astrocytes

Kim P, Choi BH

We studied the effects of organic and inorganic mercury (Hg) on the uptake of L-[3H] glutamate (L-GLU) in cultured mouse astrocytes. Following exposure to mercuric chloride (MC) [0.2 approximately 5.0...
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An unusual type of cancer-associated retinopathy in a patient with ovarian cancer

Yoon YH, Cho EH, Sohn J, Thirkill C

We studied a case of unusual retinopathy in a 35-year-old woman who presented with bilateral visual deterioration due to retinal pigmentary mottling and serous elevation in the posterior pole. Two...
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Proportional mortality ratios among Korean immigrants to New York City, 1986-1990

Stellman S

BACKGROUND: About 13,000 people immigrated to New York City from the Republic of Korea between 1986 and 1990, creating an important ethnic minority. METHODS: Using US-born Whites as a...
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Ongoing angiogenesis in blood vessels of the abdominal aortic aneurysm

Paik DC, Fu C, Bhattacharya J, David Tilson M

  • KMID: 1103319
  • Exp Mol Med.
  • 2004 Dec;36(6):524-533.
Pathogenesis of the abdominal aortic aneurysm has been attributed to neovascularization of the aortic wall. However, it is not clear whether angiogenesis persists in the aneurysm. In sections of aneurysms,...
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Oxygen, antioxidants and brain dysfunction

Choi BH

Brain is a logical target of free radical damage, considering the large lipid content of myelin sheaths and the high rate of brain oxidative metabolism. Thus, the hypothesis that free...
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Regulation of mammalian pyruvate dehydrogenase complex by phosphorylation: complexity of multiple phosphorylation sites and kinases

Patel MS, Korotchkina LG

  • KMID: 1457529
  • Exp Mol Med.
  • 2001 Dec;33(4):191-197.
This review summarizes the recent developments on the regulation of human pyruvate dehydrogenase complex (PDC) by site-specific phosphorylation by four kinases. Mutagenic analysis of the three phosphorylation sites of human...
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