- Oxidative Stress in Vivax Malaria
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Bilgin R, Yalcin MS, Yucebilgic G, Koltas IS, Yazar S
- KMID: 1792135
- Korean J Parasitol.
- 2012 Dec;50(4):375-377.
Malaria is still a leading cause of morbidity and mortality. The increase in lipid peroxidation reported in malaria infection and antioxidant status may be a useful marker of oxidative stress... -
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- Generation of Nitric Oxide in the Opossum Lower Esophageal Sphincter during Physiological Experimentation
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Lee SJ, Park H, Chang JH, Conklin JL
- KMID: 1110746
- Yonsei Med J.
- 2006 Apr;47(2):223-229.
- doi: 10.3349/ymj.2006.47.2.223
Lipopolysaccharide (LPS), given in vivo, modulates opossum esophageal motor functions by inducing the inducible nitric oxide synthase (iNOS), which increases nitric oxide (NO) production. Superoxide, a NO scavenger, is generated... -
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- Antioxidant activity of extracts from Euryale ferox seed
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Lee SE, Ju EM, Kim JH
- KMID: 1081458
- Exp Mol Med.
- 2002 May;34(2):100-106.
Euryale ferox has been widely used in traditional oriental medicine to treat a variety of illness. However, very little is known about the cellular actions by which this plant mediates... -
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- Endothelial Progenitor Cells Correlated with Oxidative Stress after Mild Traumatic Brain Injury
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Huang X, Wan D, Lin Y, Xue N, Hao J, Ma N, Pei X, Li R, Zhang W
- KMID: 2418939
- Yonsei Med J.
- 2017 Sep;58(5):1012-1017.
- doi: 10.3349/ymj.2017.58.5.1012
PURPOSE: Endothelial progenitor cells (EPCs) play a key role in tissue repair and regeneration. Previous studies have shown that infusion of human umbilical cord blood-derived endothelial colony-forming cells improves outcomes... -
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- Effects of L-NAME, a non-specific nitric oxide synthase inhibitor, on AlCl3-induced toxicity in the rat forebrain cortex
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Stevanovic ID, Jovanovic , Jelenkovic A, Colic M, Stojanovic I, Ninkovic M
- KMID: 1089341
- J Vet Sci.
- 2009 Mar;10(1):15-22.
- doi: 10.4142/jvs.2009.10.1.15
The present experiments were done to determine the effectiveness of a non-specific nitric oxide synthase inhibitor, N-nitro-L-arginine methyl ester (L-NAME), on oxidative stress parameters induced by aluminium chloride (AlCl3) intrahippocampal... -
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- Iron Supplementation in Experimental Hyperthyroidism: Effects on Oxidative Stress in Skeletal Muscle Tissue
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Seymen HO, Civelek S, Seven A, Yigit G, Hatemi H, Burcak G
- KMID: 1734122
- Yonsei Med J.
- 2004 Jun;45(3):413-418.
- doi: 10.3349/ymj.2004.45.3.413
This study was designed to investigate the effects of iron supplementation on the parameters of oxidative stress in the skeletal muscle tissue of hyperthyroidism induced rats. Hyperthyroidism was found to... -
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- The dose of cyclophosphamide for treating paraquat-induced rat lung injury
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Choi JS, Jou SS, Oh MH, Kim YH, Park MJ, Gil HW, Song HY, Hong SY
- KMID: 1503779
- Korean J Intern Med.
- 2013 Jul;28(4):420-427.
- doi: 10.3904/kjim.2013.28.4.420
BACKGROUND/AIMS: Cyclophosphamide (CP) is a promising treatment for severe cases of paraquat (PQ) poisoning. We investigated the effective dose of CP for mitigating PQ-induced lung injury. METHODS: Adult male Sprague-Dawley rats... -
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- Phagocytosis of serum-and IgG-opsonized zymos an particles induces apoptosis through superoxide but not nitric oxide in macrophage J774A.1
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Kim JS, Kwon HY, Choi WH, Jeon CY, Kim JI, Kim J, Lee JY, Kim YS, Park JB
- KMID: 1094703
- Exp Mol Med.
- 2003 Jun;35(3):211-221.
Phagocytosis of serum- and IgG-opsonized zymosan (SOZ and IOZ, respectively) particles into J774A.1 macrophages induced apoptosis of the cells, accompanied by the expression of p21(WAF1), one of cyclin-dependent protein kinase... -
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- Tempol Attenuates Renal Fibrosis in Mice with Unilateral Ureteral Obstruction: The Role of PI3K-Akt-FoxO3a Signaling
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Yoon HE, Kim SJ, Kim SJ, Chung S, Shin SJ
- KMID: 1789980
- J Korean Med Sci.
- 2014 Feb;29(2):230-237.
- doi: 10.3346/jkms.2014.29.2.230
This study investigated whether tempol, an anti-oxidant, protects against renal injury by modulating phosphatidylinositol 3-kinase (PI3K)-Akt-Forkhead homeobox O (FoxO) signaling. Mice received unilateral ureteral obstruction (UUO) surgery with or without... -
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- Protective Effects of Curcumin on Renal Oxidative Stress and Lipid Metabolism in a Rat Model of Type 2 Diabetic Nephropathy
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Kim BH, Lee ES, Choi R, Nawaboot J, Lee MY, Lee EY, Kim HS, Chung CH
- KMID: 2374087
- Yonsei Med J.
- 2016 May;57(3):664-673.
- doi: 10.3349/ymj.2016.57.3.664
PURPOSE: Diabetic nephropathy is a serious complication of type 2 diabetes mellitus, and delaying the development of diabetic nephropathy in patients with diabetes mellitus is very important. In this study,... -
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- Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies
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Ciechanover A, Kwon YT
- KMID: 2155412
- Exp Mol Med.
- 2015 Mar;47(3):e147.
- doi: 10.1038/emm.2014.117
Mammalian cells remove misfolded proteins using various proteolytic systems, including the ubiquitin (Ub)-proteasome system (UPS), chaperone mediated autophagy (CMA) and macroautophagy. The majority of misfolded proteins are degraded by the... -
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- Repeated dose toxicity of alfa-cypermethrin in rats
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Manna S, Bhattacharyya D, Mandal TK, Das S
- KMID: 1099838
- J Vet Sci.
- 2004 Sep;5(3):241-245.
The present study was performed to investigate the subacute effect of alpha-cypermethrin (alpha-CP) in rats. Alfacypermethrin a synthetic pyrethroid insecticide, dissolved in dimethyl sulfoxide (DMSO) and oral LD50 was investigated... -
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- Antidiabetic Effects of Corni Fructus Extract in Streptozotocin-Induced Diabetic Rats
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Gao D, Li Q, Gao Z, Wang L
- KMID: 1716865
- Yonsei Med J.
- 2012 Jul;53(4):691-700.
- doi: 10.3349/ymj.2012.53.4.691
PURPOSE: Diabetes is the leading cause of end-stage renal failure. The present study was undertaken to characterize the effects of Corni Fructus on diabetic nephropathy in streptozotocin-induced diabetic rats and... -
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- Biological characteristics of Chinese hamster ovary cells transfected with bovine Prnp
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Kang SG, Lee DY, Kang ML, Yoo HS
- KMID: 1089663
- J Vet Sci.
- 2007 Jun;8(2):131-137.
- doi: 10.4142/jvs.2007.8.2.131
A normal prion protein (PrPc) is converted to a proteaseresistant isoform by an apparent self-propagating activity in transmissible spongiform encephalopathy, a neurodegenerative disease. The cDNA encoding open reading frame (ORF)... -
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- The Effect of High Dose Melatonin on Cardiac Ischemia-reperfusion Injury
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Ceyran H, Narin F, Narin N, Akgun H, Ceyran AB, Ozturk F, Akcali Y
- KMID: 2158191
- Yonsei Med J.
- 2008 Oct;49(5):735-741.
- doi: 10.3349/ymj.2008.49.5.735
PURPOSE: Melatonin, the most potent scavenger of toxic free radicals, has been found to be effective in protecting against pathological states due to the release of reactive oxygen species. This... -
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- Preventive Effects of Oligomerized Polyphenol on Estradiol-Induced Prostatitis in Rats
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Kim DS, Lee EJ, Cho KS, Yoon SJ, Lee YH, Hong SJ
- KMID: 1758568
- Yonsei Med J.
- 2009 Jun;50(3):391-398.
- doi: 10.3349/ymj.2009.50.3.391
PURPOSE: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS, NIH category III) accounts for 90-95% of prostatitis cases. However, standard treatment has not yet been established. It is known that polyphenols have... -
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- Phytotherapeutic effects of Echinacea purpurea in gamma-irradiated mice
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Abouelella AM, Shahein YE, Tawfik SS, Zahran AM
- KMID: 1106213
- J Vet Sci.
- 2007 Dec;8(4):341-351.
- doi: 10.4142/jvs.2007.8.4.341
Echinacea (E.) purpurea herb is commonly known as the purple coneflower, red sunflower and rudbeckia. In this paper, we report the curative efficacy of an Echinacea extract in gamma-irradiated mice.... -
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- Down-regulation of survivin suppresses uro-plasminogen activator through transcription factor JunB
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Lee KH, Choi EY, Koh SA, Kim MK, Kim KO, Lee SH, Jang BI, Kim SW, Kim SW, Song SK, Choi JH, Kim JR
- KMID: 1022126
- Exp Mol Med.
- 2011 Sep;43(9):501-509.
- doi: 10.3858/emm.2011.43.9.057
Survivin, a member of the inhibitors of apoptosis protein family, is expressed during development and in various human cancers. However, the clinical relevance of survivin in cancer is still a... -
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- Natural compounds, fraxin and chemicals structurally related to fraxin protect cells from oxidative stress
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Whang WK, Park HS, Ham I, Oh M, Namkoong H, Kim HK, Hwang DW, Hur SY, Kim TE, Park YG, Kim JR, Kim JW
- KMID: 1089453
- Exp Mol Med.
- 2005 Oct;37(5):436-446.
Coumarins comprise a group of natural phenolic compounds found in a variety of plant sources. In view of the established low toxicity, relative cheapness, presence in the diet and occurrence... -
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