- Growth Inhibition and Apoptosis Induction of Sulindac on Human Lung Cancer Cells
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Kim HR, Yang SH, Jeong ET
- KMID: 2132977
- Tuberc Respir Dis.
- 2004 May;56(5):514-522.
- doi: 10.4046/trd.2004.56.5.514
BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAID) are useful in chemoprevention of colorectal cancers. Continuous NSAID administation causes 40% to 50% reduction in relative risk for colorectal cancer. Sulindac possesses an antiproliferative... -
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- Sulindac-induced Cholestatic Hepatitis and Acute Pancreatitis in a Patient having Systemic Sclerosis with Anti-RNP Antibody: report of a case
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Chang HK, Kim YS, Jeong H, Park SO, Kim SH, Ko H, Kang GH, Kim JU
- KMID: 2202477
- J Korean Rheum Assoc.
- 2000 Jun;7(2):185-189.
Sulindac is a commonly used nonsteroidal anti-inflammatory drug (NSAID). It is relatively economical and seems to be less nephrotoxic due to its property of minimal renal prostaglandin inhibition. Although... -
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- Effect of Lactacystin on the Sulindac-Induced Apoptosis Mechanisms in HT-29 Cells
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Kim JM, Park KJ, Kim SH, Choi HJ
- KMID: 2334296
- J Korean Soc Coloproctol.
- 2003 Apr;19(2):61-66.
PURPOSE: One of possible mechanisms of the antineoplastic effect by nonsteroidal anti-inflammatory drugs (NSAIDs) is an induction of apoptosis. The NSAIDs-induced apoptosis appears to be caspase- and mitochondria-dependent. The ubiquitin-proteasome... -
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- Sulindac Prevents Esophageal Adenocarcinomas Induced by Gastroduodenal Reflux in Rats
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Kim SW, Jang TJ, Jung KH, Suh JI
- KMID: 1786219
- Yonsei Med J.
- 2007 Dec;48(6):1020-1027.
- doi: 10.3349/ymj.2007.48.6.1020
PURPOSE: It is known that cyclooxygenase (COX)-2 expression is increased in Barrett's esophagus and esophageal adenocarcinomas. We studied COX-2 expression and the effect sulindac has on the genesis of... -
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- Regression of Colonic Adenomas After Treatment With Sulindac in Familial Adenomatous Polyposis: A Case With a 2-Year Follow-up Without a Prophylactic Colectomy
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Kim KY, Jeon SW, Park JG, Yu CH, Jang SY, Lee JK, Hwang HY
- KMID: 2169745
- Ann Coloproctol.
- 2014 Aug;30(4):201-204.
- doi: 10.3393/ac.2014.30.4.201
Familial adenomatous polyposis (FAP) is an autosomal dominant disorder characterized by hundreds of colorectal adenomatous polyps that progress to colorectal cancer. Management of patients with FAP is with a total... -
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- Synergistic Effect of Sulindac and Simvastatin on Apoptosis in Lung Cancer A549 Cells through AKT-Dependent Downregulation of Survivin
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Kim YS, Seol CH, Jung JW, Oh SJ, Hwang KE, Kim HJ, Jeong ET, Kim HR
- KMID: 2380394
- Cancer Res Treat.
- 2015 Jan;47(1):90-100.
- doi: 10.4143/crt.2013.194
PURPOSE: Non-steroidal anti-inflammatory drugs (NSAIDs) and statins are potential chemopreventive or chemotherapeutic agents. The mechanism underlying the deregulation of survivin by NSAIDs and statins in human non-small cell lung cancer... -
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- Familial Adenomatous Polyposis Improved by COX-2 Inhibitor in a Child
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Oh KW, Kim SY, Lee HS, Lee MH, Choe BH
- KMID: 2207110
- J Korean Pediatr Soc.
- 2002 Dec;45(12):1591-1595.
Familial adenomatous polyposis(FAP) is an autosomal dominant disease characterized by numerous adenomas in the colorectum. Patients with FAP are always at risk of malignant transformation, so that colectomy is unavoidable.... -
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- Combination Treatment with Arsenic Trioxide and Sulindac Induces Apoptosis of NCI-H157 Human Lung Carcinoma Cells via ROS Generation with Mitochondrial Dysfunction
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Kim HR, Yang SH, Jeong ET
- KMID: 2318635
- Tuberc Respir Dis.
- 2005 Jul;59(1):30-38.
BACKGROUND: Arsenic trioxide (As2O3) has been used to treat acute promyelocytic leukemia, and it induces apoptosis in a variety of solid tumor cell lines including non-small cell lung cancer cells.... -
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- A Combined Treatment of Tamoxifen, Goserelin, and Sulindac in 2 Cases of Recurrent Desmoid Tumor in the Abdomen
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Kim HC, Suh BS, Lee DH, Ahn BY, Chung CS, Kang GH, Ha HK, Kim JC
- KMID: 2142366
- J Korean Soc Coloproctol.
- 1999 Oct;15(4):339-343.
Desmoid tumor is a subtype of fibromatosis arising from deep fascial or soft tissue structure. It is characterized by locally aggressive behavior with a tendency to local recurrence, but is... -
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- Inducing Apoptosis of NCI-H157 Human Lung Carcinoma Cells via Activation of Caspase Cascade by Combination Treatment with Arsenic Trioxide and Sulindac
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Kim HR, Yang SH, Jeong ET
- KMID: 2318477
- Tuberc Respir Dis.
- 2004 Apr;56(4):381-392.
Arsenic trioxide(As2O3) was introduced into the treatment of refractory or relapsed acute promyelocytic leukemia. Some investigators have reported that arsenic trioxide had induced apoptosis in a variety of solid human... -
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- Sulindac-induced Apoptosis without Oligonucleosomal DNA Fragmentation in HT-29 Cells: Its Special References to Mitochondrial Pathway
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Park KJ, Kwon Y, Kim SH, Kim MC, Choi HJ, Kim YH, Cho SH, Jung GJ, Kim SH, Kwon HC
- KMID: 1566533
- J Korean Soc Coloproctol.
- 2004 Aug;20(4):191-198.
PURPOSE: This study was undertaken to reveal the molecular mechanism underlying sulindac-induced apoptosis in the human colon cancer cell line HT-29 (mutant p53). METHODS: Apoptosis was determined by using Hoechst... -
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- Sulindac Sulfide-induced Apoptosis is Caspase 3-Dependent in Maxillary Cancer Cells
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Kim DY, Song KS, Moon IS, Yoon JH
- KMID: 1611639
- Korean J Otolaryngol-Head Neck Surg.
- 2002 Dec;45(12):1157-1161.
BACKGROUND AND OBJECTIVES: Head and neck cancer is the sixth most common cancer in human body. Squamous cell cancer (SCC) accounts for most of sinonasal cancers. Prediction of cancer development... -
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- Phosphorylation of Glycogen Synthase Kinase-3beta(S9) Induced Neuronal Cell Survival by Sulindac in the Rat Retina
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Choi SM, Choi JS, Joo CK
- KMID: 2206621
- J Korean Ophthalmol Soc.
- 2003 Mar;44(3):721-726.
PURPOSE: Inactivation of glycogen synthase kinase-3beta (GSK-3beta) by S9 phosphorylation is implicated in neuronal cell survival. In this study, we examined the involvement of GSK-3betaS9) phosphorylation on retina cell survival... -
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- A Novel Germline Mutation in Exon 15 of the APC Gene in Attenuated Familial Adenomatous Polyposis: A Report of Two Cases
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Jahng J, Yoon SJ, Park H
- KMID: 2053526
- Gut Liver.
- 2013 Jan;7(1):120-125.
Attenuated familial adenomatous polyposis (AFAP) is a variant of familial adenomatous polyposis with fewer than one hundred colorectal polyps and a later age of onset of the cancer. Here, we... -
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- Expression of Cyclooxygenase-2 in Colorectal Cancer and Adenoma
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Kim JW, Jung G, Han SH, Jeong HJ, Do JH, Chang SK
- KMID: 2240354
- Korean J Gastroenterol.
- 2000 Apr;35(4):448-457.
BACKGROUND/AIMS: Several epidemiological and animal studies suggest that the use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin and sulindac, decreases the risk of colorectal cancer and adenoma. A likely mechanism by... -
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- A Case of Graft Intolerance Syndrome Treated by Percutaneous Renal Artery Embolization
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Sim YS, Yoo SH, Baik SJ, Lee YS, Kim SJ, Kang DH, Yoon KI, Kang BC, Choi KB
- KMID: 2079510
- Korean J Nephrol.
- 2005 Jul;24(4):674-679.
In patients with renal transplant failure's the graft can be left in situ when there are no additional complications. Graft intolerance occurs in some failed renal grafts when the immunological... -
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- AClinical Resutlt of Modified Phemister Method for Acute Acromioclavicular Dislocation
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Cho DY, Kim JH, Kim KC
- KMID: 2311525
- J Korean Fract Soc.
- 1998 Oct;11(4):947-952.
There are many procedures for the treatment of acute A-C injury which have many complic ation such as limitation of shoulder motion, post traumatic arthritis and recurrence of dislocation etc.... -
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- A case of minimal change glomerulopathy without interstitial nephritis induced by non-opiate analgesics
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Li JH, Shim H, Yeom JJ, Lee MS, Park BH, Oh SK, Kim NH, Park MR, Ahn SH, Song JH
- KMID: 2252864
- Korean J Med.
- 2002 Aug;63(2):209-213.
The use of nonsteroidal antiinflammatory drugs (NSAIDs) can be complicated by severe forms of renal dysfunction. These include fluid and electrolyte abnormalities, acute renal insufficiency due to alteration in renal... -
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- Peripheral Bronchopleural Fistula: CT Evaluation in 22 patients
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Lee Y, Kim MY, Choi SH, Kim EJ, Lee JJ, Kim O
- KMID: 2103263
- J Korean Radiol Soc.
- 1999 Jan;40(1):67-71.
- doi: 10.3348/jkrs.1999.40.1.67
PURPOSE: To determine the usefulness of CT for the evaluation of peripheral bronchopleural fistulas. MATERIALS AND METHODS: CT scans of 22 patients with persistent air leak, as seen on serial... -
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- Analysis on Effect of Health Promotion Program for the Patients with Rheumatoid Arthritis
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Oh HS, Kim YR, Park W, Song JS
- KMID: 2374983
- J Korean Acad Nurs.
- 2000 Apr;30(2):342-353.
This study was performed to examine the effect of a 7-week comprehensive health promotion program for improving pain, depression, and disability by employing a quasi-experimental design. The subjects were regular... -
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